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Aceclofenac + Paracetamol/acetaminophen + Serratiopeptidase


Uses of Aceclofenac + Paracetamol/acetaminophen + Serratiopeptidase

Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase combines three analgesic and anti-inflammatory medicines, which are used to relieve swelling and inflammation linked to surgery, trauma, infection, and various painful inflammatory conditions.

Side effects of Aceclofenac + Paracetamol/acetaminophen + Serratiopeptidase

  • Nausea
  • Vomiting 
  • Diarrhoea
  • Constipation 
  • Abdominal pain 
  • Dyspepsia

How Aceclofenac + Paracetamol/acetaminophen + Serratiopeptidase works

  • Aceclofenac functions by blocking the activity of cyclooxygenase (COX), a factor in the production of prostaglandins (PG), responsible for pain, swelling, inflammation, and fever.
  • Paracetamol/Acetaminophen exerts its central analgesic effect by activating descending serotonergic pathways. Its primary site of action may involve inhibiting prostaglandin (PG) synthesis or influencing cannabinoid receptors through an active metabolite.
  • Serratiopeptidase, a proteolytic enzyme, alleviates pain and swelling without inhibiting prostaglandins, avoiding gastrointestinal adverse effects. Its actions include improving blood circulation through a proteolytic effect, eliminating damaged proteins and cellular debris, and regulating inflammatory cytokines.

Certified content

Written By

Amit SharmaClinical Health & Medical Writer| 3 Years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 Years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase is available for use via the oral route (tablets).

Age and Dose Restrictions

  • The combination of Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase is meant for adults and children above 18 years of age.


  • Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase is contraindicated in patients with known allergies to aceclofenac or paracetamol or to serratiopeptidase, have peptic ulcer, bleeding disorders, history of heart, hepatic or renal failure, have asthma, urticaria, or acute rhinitis.

Other Medications To Avoid With This Medicine

  • It's not recommended to take painkillers like nimesulide, oxyphenbutazone, and metamizole, as well as blood clotting agent warfarin, alongside this combination because they might interact with each other.

Overdose and Missed Dose

  • Overdose of Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase can cause headache, nausea, vomiting, epigastric pain, gastrointestinal (GI) irritation, and GI bleeding. Inform your doctor regarding these effects and follow the advice accordingly.
  • If you forget an Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase dose, take it as soon as you remember but avoid repeating the dose.

Use in Pregnancy and Lactation

  • Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase is not recommended in pregnant and breastfeeding women.

Use In Driving And Operating Machinery

  • Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase may affect your ability to drive or operate heavy machinery as contains aceclofenac. Avoid driving if you feel dizzy after taking this combination.

Special Dietary & Lifestyle Recommendation

  • Lifestyle changes, including dietary modifications and regular low-impact exercise, are essential when taking Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase to manage pain.
  • Take Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase after food to prevent GI-related side effects.
  • Avoid alcohol when you are taking Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase.

Frequently asked questions

Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase can relieve pain and inflammation within a few hours after ingestion.

It is contraindicated for patients with renal or hepatic issues. Also, it is not recommended for pregnant and breastfeeding women.

Yes, Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase combination is typically prescribed for a brief duration and can be stopped once your symptoms diminish. Always follow your doctor's advice on whether to continue the medication.

Exercise caution while taking Aceclofenac + Paracetamol/Acetaminophen + Serratiopeptidase if you have severe kidney or liver problems, as it is contraindicated in such patients.

Terms & Conditions

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