Home/Drugs By Ailments / Caffeine + Cetirizine + Nimesulide + Paracetamol/acetaminophen + Phenylephrine

Caffeine + Cetirizine + Nimesulide + Paracetamol/acetaminophen + Phenylephrine

Uses of Caffeine + Cetirizine + Nimesulide + Paracetamol/acetaminophen + Phenylephrine

  • The primary use of Caffeine + Cetirizine + Nimesulide + Paracetamol/Acetaminophen + Phenylephrine is for the symptomatic relief of the common cold and influenza symptoms. This medication belongs to the group of multi-symptom cold relief medicines.
  • Secondary uses include providing relief from headache, minor aches and pains, nasal congestion, runny nose, sneezing, itching, watery eyes, and fever associated with these conditions.

Side effects of Caffeine + Cetirizine + Nimesulide + Paracetamol/acetaminophen + Phenylephrine

  • Drowsiness
  • Headache
  • Nausea
  • Dry mouth
  • Increased blood pressure

How Caffeine + Cetirizine + Nimesulide + Paracetamol/acetaminophen + Phenylephrine works

  • Caffeine + Cetirizine + Nimesulide + Paracetamol / Acetaminophen + Phenylephrine is a comprehensive cold and flu relief combination.
  • Caffeine, a mild central nervous system stimulant, works by reducing fatigue and drowsiness, therefore, making you feel more alert.
  • Cetirizine is a second-generation antihistamine, it functions by blocking histamine, a substance in the body that causes allergic symptoms such as runny nose, sneezing, itching and watery eyes.
  • Nimesulide is a non-steroidal anti-inflammatory medicine. It works by blocking the release of certain chemical messengers that cause inflammation, fever and mild pain.
  • Paracetamol / Acetaminophen is an analgesic and antipyretic. It effectively relieves headache and muscle aches by blocking chemical messengers in the brain that tell us we have pain. It also reduces fever by affecting the heat-regulating centres in the brain.
  • Phenylephrine is a decongestant that works by shrinking swollen nasal membranes. It achieves this by constricting (shrinking) blood vessels in the nasal passages, thereby relieving a blocked nose.

Certified content

Written By

docImg
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Caffeine + Cetirizine + Nimesulide + Paracetamol / Acetaminophen + Phenylephrine is available as oral tablets. This formulation allows for convenient administration and dosage control.

Age and Dose Restrictions

  • This medicine is intended for use by adults and adolescents over the age of 12 years. It is not recommended for use in children below 12 years of age due to the potential risk and lack of data on safety and efficacy.

Contraindications

  • This medicine is contraindicated in patients with hypersensitivity to any of the ingredients.
  • It should not be used by individuals with severe hypertension, coronary artery disease, or severe liver impairment.

Other Medications to Avoid

  • Caffeine + Cetirizine + Nimesulide + Paracetamol / Acetaminophen + Phenylephrine can interact with CNS depressants (such as barbiturates), anticoagulants (like warfarin), MAOIs (such as selegiline), SSRIs (like fluoxetine), beta-blockers (such as propranolol), and other decongestants or blood pressure medications.
  • Before starting any new prescription or over-the-counter medications, always consult your doctor to avoid potential interactions.

Overdose and Missed Dose

  • Overdosing can lead to serious health issues including severe liver damage due to excess paracetamol. Early symptoms include nausea, vomiting, abdominal pain, pale skin, sweating, and loss of appetite. Later symptoms may indicate liver damage like yellowing of the skin and eyes, confusion, dark urine, and coma. If you suspect an overdose, seek immediate medical attention.
  • If you miss a dose, take it as soon as you remember. If it is near the time of your next dose, skip the missed dose. Do not double up on doses to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless, resolving once the medicine is discontinued. However, if you experience any severe side effects or worsening of any symptoms, consult your doctor.

  • Drinking plenty of water can help manage mild side effects like dry mouth.
  • If you experience headaches, resting or placing a cold compress over your forehead may provide relief.

Use in Driving and Operating Machinery

  • Caffeine + Cetirizine + Nimesulide + Paracetamol / Acetaminophen + Phenylephrine may cause drowsiness or dizziness. Avoid driving or operating heavy machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

  • The use of this medicine during pregnancy or breastfeeding should only be done under the supervision of a doctor. Always consult your doctor before using any medication during these periods.

Caution in Other Conditions

  • Extra care should be taken by patients with liver or kidney impairment, G6PD deficiency, or asthma before starting this combination medication.

Special Dietary and Lifestyle Recommendations

  • To reduce the risk of catching colds and flu, maintain a balanced diet rich in vitamins and minerals to support your immune system.
  • Regular sleep can help your body recover faster from illness.
  • Hydrate regularly to soothe congestion and to keep your body functioning well.
  • Avoid close contact with sick people and practice good hygiene, such as washing hands regularly, to prevent the spread of viruses.

Frequently asked questions

Caffeine may affect mood and appetite, while Cetirizine can cause drowsiness. Nimesulide, Paracetamol/Acetaminophen, and Phenylephrine typically have minimal effects on appetite or mood. If you experience significant changes, consult your doctor.

Yes, one of the side effects of this combination can be drowsiness or fatigue, particularly due to the presence of Cetirizine, which is an antihistamine.

This medicine usually requires a prescription from a doctor and is not typically available over the counter.

Patients with kidney disease should consult their doctor before taking this medicine, as it contains paracetamol and Nimesulide, which can affect kidney function.

This medicine contains Phenylephrine, a decongestant that can potentially raise blood pressure. Therefore, it is recommended that patients with hypertension or high blood pressure consult their doctor before use.

This combination can be used daily for short-term symptom relief as directed. Prolonged use should be avoided without consulting your doctor to prevent potential side effects and interactions.

Relief from symptoms such as pain, fever, and congestion can typically be felt within 30 to 60 minutes after taking the combination, though it may vary depending on the individual and the severity of symptoms.

Terms & Conditions


Caffeine + Cetirizine + Nimesulide + Paracetamol/acetaminophen + Phenylephrine in other salts

ACECLOFENAC + PARACETAMOL/ACETAMINOPHENACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASECETIRIZINEDICLOFENAC + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHENIBUPROFEN + PARACETAMOL/ACETAMINOPHENNIMESULIDE + PARACETAMOL/ACETAMINOPHENLEVOCETIRIZINELEVOCETIRIZINE + MONTELUKASTNIMESULIDECETIRIZINE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINEPARACETAMOL + CAFFEINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINE HYDROCHLORIDEAMBROXOL + LEVOCETIRIZINELEVOCETIRIZINE + PSEUDOEPHEDRINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + RABEPRAZOLENIMESULIDE + TIZANIDINECHLORPHENIRAMINE + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINEDEXTROPROPOXYPHENE + PARACETAMOL/ACETAMINOPHENDICLOFENAC + NIMESULIDECPM + DEXTROMETHORPHAN + PHENYLEPHRINELORNOXICAM + PARACETAMOL/ACETAMINOPHENNIMESULIDE + SERRATIOPEPTIDASENIMESULIDE + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDEXTROPROPOXYPHENE + DICYCLOMINE + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHEN + TRAMADOLAMBROXOL + LEVOCETIRIZINE + MONTELUKASTDEXIBUPROFEN + PARACETAMOL/ACETAMINOPHENDICYCLOMINE + PARACETAMOL/ACETAMINOPHEN + TRAMADOLDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDECETIRIZINE + PSEUDOEPHEDRINECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRYPSIN-CHYMOTRYPSINCHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECAFFEINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEBECLOMETHASONE DIPROPIONATE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINECALCIUM DOBESILATE + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINE + TROXERUTIN + ZINC OXIDEDICYCLOMINE + NIMESULIDEPHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDEPARACETAMOL/ACETAMINOPHEN + RACEMETHIONINECARBOXY METHYL CELLULOSE + NAPHAZOLINE + PHENYLEPHRINENAPHAZOLINE + PHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECPM + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORBUTOL + PHENYLEPHRINE + TROPICAMIDECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE + DEXTROMETHORPHAN + MENTHOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESINBROMHEXINE + GUAIFENESIN + PHENYLEPHRINEBROMHEXINE + PHENYLEPHRINE + SALBUTAMOLAMBROXOL + GUAIFENESIN + LEVOCETIRIZINE + MENTHOLBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEPHENYLEPHRINE + TROPICAMIDECAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECAMYLOFIN + PARACETAMOL/ACETAMINOPHENCHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATEPARACETAMOL/ACETAMINOPHEN + PROMETHAZINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDEDOMPERIDONE + PARACETAMOL/ACETAMINOPHENCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHENMETOCLOPRAMIDE + PARACETAMOL/ACETAMINOPHENDOMPERIDONE + FLUNARIZINE + PARACETAMOL/ACETAMINOPHENONDANSETRON + PARACETAMOL/ACETAMINOPHENAMBROXOL + CETIRIZINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PHENYLEPHRINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINECHLORPHENIRAMINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINEBROMHEXINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + GUAIFENESIN + PHENYLEPHRINEAMBROXOL + CETIRIZINE + DEXTROMETHORPHANDEXTROMETHORPHAN + PHENYLEPHRINE + TRIPROLIDINEAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + MENTHOL + PHENYLEPHRINELEVOCETIRIZINE + PHENYLEPHRINECETIRIZINE + DEXTROMETHORPHANCETIRIZINE + DEXTROMETHORPHAN + PSEUDOEPHEDRINEAMBROXOL + GUAIFENESIN + LEVOCETIRIZINE + PHENYLEPHRINEIBUPROFEN + MAGNESIUM TRISILICATE + PARACETAMOL/ACETAMINOPHENBROMHEXINE + DEXTROMETHORPHAN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DIETHYLCARBAMAZINECETIRIZINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + MENTHOL + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESIN + PHENYLEPHRINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TIZANIDINEACEBROPHYLLINE + LEVOCETIRIZINE + MONTELUKASTPARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRAMADOLCHLORZOXAZONE + PARACETAMOL/ACETAMINOPHENCAFFEINE + IBUPROFEN + PARACETAMOL/ACETAMINOPHENDOMPERIDONE + PARACETAMOL/ACETAMINOPHEN + TRAMADOLPARACETAMOL/ACETAMINOPHEN + TAPENTADOLDICYCLOMINE + PAMABROM + PARACETAMOL/ACETAMINOPHENIBUPROFEN + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASECAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECETIRIZINE + PHENYLEPHRINEAMBROXOL + LEVOCETIRIZINE + PSEUDOEPHEDRINECAFFEINE + DIPHENHYDRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEASPIRIN + CAFFEINECAMYLOFIN + NIMESULIDEDICLOFENAC + METHOCARBAMOL + PARACETAMOL/ACETAMINOPHENHYOSCINE + PARACETAMOL/ACETAMINOPHENETORICOXIB + PARACETAMOL/ACETAMINOPHENCETIRIZINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRYPSIN-CHYMOTRYPSINFEXOFENADINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECODEINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHENDICLOFENAC + DICYCLOMINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENAZONEBROMHEXINE + CPM + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDEXTROPROPOXYPHENE + NIMESULIDE + PARACETAMOL/ACETAMINOPHENDROTAVERINE + PARACETAMOL/ACETAMINOPHENDICYCLOMINE + MEFENAMIC ACID + PARACETAMOL/ACETAMINOPHENETODOLAC + PARACETAMOL/ACETAMINOPHENLORNOXICAM + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TIZANIDINEDEXKETOPROFEN + PARACETAMOL/ACETAMINOPHENBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORZOXAZONE + NIMESULIDE + PARACETAMOL/ACETAMINOPHENAMBROXOL + LEVOCETIRIZINE + PHENYLEPHRINECHLORZOXAZONE + DICLOFENAC SODIUM + PARACETAMOL/ACETAMINOPHENCHLORZOXAZONE + IBUPROFEN + PARACETAMOL/ACETAMINOPHENCHLORZOXAZONE + NIMESULIDEPARACETAMOL/ACETAMINOPHEN + TOLPERISONECAFFEINE + CETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDEXTROPROPOXYPHENE + DICLOFENAC + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHEN + PROCHLORPERAZINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + ERGOTAMINE + PARACETAMOL/ACETAMINOPHEN + PROCHLORPERAZINELEVOCETIRIZINE + NIMESULIDE + PHENYLEPHRINEPARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEAMBROXOL + CETIRIZINE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CETIRIZINE + NIMESULIDE + PHENYLEPHRINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN
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