Home/Drugs By Ailments / Domperidone + Flunarizine + Paracetamol/acetaminophen

Domperidone + Flunarizine + Paracetamol/acetaminophen

Uses of Domperidone + Flunarizine + Paracetamol/acetaminophen

  • Domperidone + Flunarizine + Paracetamol/Acetaminophen is primarily used to prevent migraine headaches, particularly those with severe nausea and vomiting. This medication belongs to the group of anti-nausea, calcium channel blockers, and analgesics.

Side effects of Domperidone + Flunarizine + Paracetamol/acetaminophen

  • Drowsiness and fatigue

  • Weight gain and increased appetite

  • Dry mouth and abdominal discomfort

  • Depression and mood changes

  • Skin rash

How Domperidone + Flunarizine + Paracetamol/acetaminophen works

  • Domperidone + Flunarizine + Paracetamol/Acetaminophen is a prophylactic combination intended for managing migraines.

  • Domperidone is an anti-nausea medicine that works by opposing dopamine receptors in the stomach and intestines, reducing feelings of nausea and vomiting. It also helps to speed up the process of emptying the stomach.

  • Flunarizine is a calcium channel blocker. It functions by preventing changes in blood vessels in the brain and inhibiting processes that can lead to inflammation in these vessels. As a result, it helps to prevent migraines.

  • Paracetamol/Acetaminophen is an analgesic and antipyretic medicine. It reduces pain and fever by blocking the production of prostaglandins in the brain, which are responsible for these symptoms.

  • Together, these medicines help to prevent migraines and other associated symptoms such as headaches, nausea, vomiting, and sensitivity to light or sound when taken regularly.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Domperidone + Flunarizine + Paracetamol/Acetaminophen is available for oral use in the form of tablets and capsules.

Age and Dose Restrictions

  • This medicine is intended for use by adults only.

Contraindications

  • This combination is contraindicated in patients with hepatic impairment.

  • It is also contraindicated in those with cardiac arrhythmias, congestive heart failure, or a prolonged QT interval.

  • Additionally, it should not be used by individuals with Parkinson's disease, pheochromocytoma, porphyria, or epilepsy.

Other Medications to Avoid

  • This combination may interact with CYP3A4 inhibitors (such as erythromycin, and ketoconazole), calcium channel blockers (like verapamil, and diltiazem), and CNS depressants (such as benzodiazepines).

Overdose and Missed Dose

  • An overdose of Domperidone + Flunarizine + Paracetamol/Acetaminophen may lead to severe liver injury, cardiac issues, or nervous system effects such as dizziness and confusion. Immediate medical attention should be sought if an overdose is suspected.

  • If a dose is missed, it should be taken as soon as remembered unless it is close to the time for your next dose. In that case, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For drowsiness caused by Flunarizine, consider taking the medication at bedtime to minimise impact during daytime activities.

  • If you experience dry mouth from Domperidone, sipping water regularly can help alleviate discomfort.

Use in Driving and Operating Machinery

  • Domperidone + Flunarizine + Paracetamol/Acetaminophen may cause drowsiness or dizziness. You should avoid driving or operating heavy machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

  • This combination is contraindicated during pregnancy and lactation. Components like Domperidone have been shown to be excreted in breast milk. The risk of adverse effects on the foetus has also been reported.

  • Always consult your doctor before using this medication if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Caution is advised when using Domperidone + Flunarizine + Paracetamol/Acetaminophen in elderly patients due to an increased sensitivity to side effects such as drowsiness and cardiac effects.

  • Patients with renal impairment must also be cautious; dose adjustments may be necessary to avoid accumulation of the medicine components, which can increase the risk of adverse effects.

Special Dietary and Lifestyle Recommendations

  • It is recommended to keep a migraine diary to identify potential food triggers. Common triggers include aged cheeses, red wine, processed meats, and chocolate.

  • Stay hydrated throughout the day; dehydration can trigger migraines in some individuals.

  • Limit caffeine consumption, as excessive intake can lead to withdrawal headaches, which might mimic or trigger migraines.

Frequently asked questions

No, Domperidone + Flunarizine + Paracetamol/Acetaminophen is not a steroid. This combination contains an anti-nausea medication, a calcium channel blocker, and a mild pain reliever and fever reducer.

Domperidone + Flunarizine + Paracetamol/Acetaminophen might cause drowsiness in some individuals, especially due to the presence of flunarizine. It is therefore recommended to be taken at bedtime.

There is no evidence to suggest that this medicine affects fertility. However, if you are trying to conceive, you should consult your doctor before starting any new medication.

No specific dietary restrictions are known for this medicine. However, it is generally advisable to maintain a balanced diet while taking any medication.

This medicine should be taken as advised by your doctor, who will decide the dosage and frequency based on your condition and response to treatment.

The onset of action can vary for each individual and the specific condition being managed. Your doctor will provide you with more specific information based on your health status.

This combination medicine is not typically available over the counter and usually requires a prescription from a doctor.

Terms & Conditions


Domperidone + Flunarizine + Paracetamol/acetaminophen in other salts

ACECLOFENAC + PARACETAMOL/ACETAMINOPHENACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL/ACETAMINOPHENDOMPERIDONE + OMEPRAZOLEDOMPERIDONE + RABEPRAZOLEPARACETAMOL/ACETAMINOPHENIBUPROFEN + PARACETAMOL/ACETAMINOPHENDOMPERIDONE + ESOMEPRAZOLENIMESULIDE + PARACETAMOL/ACETAMINOPHENDOMPERIDONENAPROXEN + DOMPERIDONEFLUNARIZINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + RABEPRAZOLEFLUNARIZINE + PROPRANOLOLDEXRABEPRAZOLE + DOMPERIDONEDEXTROPROPOXYPHENE + PARACETAMOL/ACETAMINOPHENCINNARIZINE + DOMPERIDONEDOMPERIDONE + ILAPRAZOLEDOMPERIDONE + LAFUTIDINEDOMPERIDONE + LANSOPRAZOLELORNOXICAM + PARACETAMOL/ACETAMINOPHENNIMESULIDE + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDEXTROPROPOXYPHENE + DICYCLOMINE + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHEN + TRAMADOLDEXIBUPROFEN + PARACETAMOL/ACETAMINOPHENDICYCLOMINE + PARACETAMOL/ACETAMINOPHEN + TRAMADOLDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEDOMPERIDONE + RANITIDINECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRYPSIN-CHYMOTRYPSINCAFFEINE + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDEPARACETAMOL/ACETAMINOPHEN + RACEMETHIONINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECPM + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDOMPERIDONE + SUCRALFATECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATEDOMPERIDONE + MAGALDRATE + SIMETHICONECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECAMYLOFIN + PARACETAMOL/ACETAMINOPHENCHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATEPARACETAMOL/ACETAMINOPHEN + PROMETHAZINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDOMPERIDONE + PARACETAMOL/ACETAMINOPHENCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHENMETOCLOPRAMIDE + PARACETAMOL/ACETAMINOPHENDOMPERIDONE + RANITIDINE + SIMETHICONEONDANSETRON + PARACETAMOL/ACETAMINOPHENLEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEBROMHEXINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEIBUPROFEN + MAGNESIUM TRISILICATE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TIZANIDINEPARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRAMADOLCHLORZOXAZONE + PARACETAMOL/ACETAMINOPHENCAFFEINE + IBUPROFEN + PARACETAMOL/ACETAMINOPHENDOMPERIDONE + PARACETAMOL/ACETAMINOPHEN + TRAMADOLPARACETAMOL/ACETAMINOPHEN + TAPENTADOLDICYCLOMINE + PAMABROM + PARACETAMOL/ACETAMINOPHENIBUPROFEN + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASECAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + DIPHENHYDRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDICLOFENAC + METHOCARBAMOL + PARACETAMOL/ACETAMINOPHENHYOSCINE + PARACETAMOL/ACETAMINOPHENETORICOXIB + PARACETAMOL/ACETAMINOPHENCETIRIZINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRYPSIN-CHYMOTRYPSINFEXOFENADINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECODEINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHENDICLOFENAC + DICYCLOMINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENAZONEBROMHEXINE + CPM + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDEXTROPROPOXYPHENE + NIMESULIDE + PARACETAMOL/ACETAMINOPHENDROTAVERINE + PARACETAMOL/ACETAMINOPHENDICYCLOMINE + MEFENAMIC ACID + PARACETAMOL/ACETAMINOPHENETODOLAC + PARACETAMOL/ACETAMINOPHENLORNOXICAM + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TIZANIDINEDEXKETOPROFEN + PARACETAMOL/ACETAMINOPHENBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORZOXAZONE + NIMESULIDE + PARACETAMOL/ACETAMINOPHENCHLORZOXAZONE + DICLOFENAC SODIUM + PARACETAMOL/ACETAMINOPHENCAFFEINE + CETIRIZINE + NIMESULIDE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORZOXAZONE + IBUPROFEN + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHEN + TOLPERISONECAFFEINE + CETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDEXTROPROPOXYPHENE + DICLOFENAC + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHEN + PROCHLORPERAZINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + ERGOTAMINE + PARACETAMOL/ACETAMINOPHEN + PROCHLORPERAZINEPARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEAMBROXOL + CETIRIZINE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN
Available medicines for DOMPERIDONE + FLUNARIZINE + PARACETAMOL/ACETAMINOPHEN
Migrest 10/5/500 MG Tablet 10
Migrest 10/5/500 MG Tablet 10
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Pack of 10 Units
₹51.66
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Nomigan Dp 10/5/500 MG Tablet 10
Nomigan Dp 10/5/500 MG Tablet 10
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₹34.85
MRP ₹42.50
18.00% OFF
Zerograin Plus 10/5/325 MG Tablet 10
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Mankind Pharmaceuticals Ltd.
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₹57.24
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18.00% OFF
Migcalm Plus Tablet 10
Migcalm Plus Tablet 10
Aspire Remedies
Pack of 10 Units
₹32.80
MRP ₹40.00
18.00% OFF
Blomig P 10/5/500 MG Tablet 10
Blomig P 10/5/500 MG Tablet 10
Ordain Healthcare Pvt. Ltd
Pack of 10 Units
₹32.80
MRP ₹40.00
18.00% OFF
Migrest Suspension 60 ML
Migrest Suspension 60 ML
Tidal Laboratories Pvt Ltd
Pack of 60 ML
₹35.15
MRP ₹42.86
18.00% OFF
Migrid 10/5/500 MG Tablet 10
Migrid 10/5/500 MG Tablet 10
Medinova Labs
Pack of 10 Units
₹39.98
MRP ₹48.75
18.00% OFF
Migrasaf Tablet 10
Migrasaf Tablet 10
Saf Fermion Ltd
Pack of 10 Units
₹82.00
MRP ₹100.00
18.00% OFF

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