Diclofenac + Paracetamol/Acetaminophen + Trypsin-Chymotrypsin is primarily used for relieving pain and inflammation in various musculoskeletal conditions and belongs to the class of analgesics and anti-inflammatory medicines.
Additionally, it is also prescribed for conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute musculoskeletal pain, lower back pain, post-traumatic pain, post-operative pain, dental pain, and dysmenorrhea.
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Diclofenac + Paracetamol/Acetaminophen + Trypsin-Chymotrypsin is a combination medicine used for pain and inflammation management.
Diclofenac is a non-steroidal anti-inflammatory medication (NSAID). It functions by blocking the action of cyclooxygenase (COX) enzymes in the body, which play a key role in the production of chemicals called prostaglandins. By decreasing the formation of these prostaglandins, Diclofenac helps lessen inflammation and pain at the site of injury.
Paracetamol/Acetaminophen forms the analgesic component of this combination. It is thought to work by inhibiting COX enzymes in the brain and spinal cord, effectively increasing the body's threshold for pain. This action provides relief from discomfort and also reduces fever.
Trypsin and Chymotrypsin are proteolytic enzymes, which means they break down proteins into their smaller components, such as peptides and amino acids. They aid in clearing away debris from injury or surgery sites, promote tissue healing, and enhance blood supply to the affected areas. They work together with Diclofenac and Paracetamol/Acetaminophen to provide comprehensive management of pain and inflammation in various conditions.
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BMS, FMC, MD Resident
Diclofenac + Paracetamol/Acetaminophen + Trypsin-Chymotrypsin is available for use via the oral route in the form of enteric-coated tablets.
This medicine is meant for adults and children above 12 years of age.
This medicine is contraindicated in patients with known hypersensitivity to any ingredient.
This medicine is contraindicated in patients with active peptic ulcer disease or gastrointestinal bleeding.
This medicine is contraindicated in patients with severe liver or kidney impairment.
This medicine is contraindicated in patients with a history of asthma, urticaria, or allergic reactions to NSAIDs.
This combination may interact with anticoagulants (such as warfarin and heparin), SSRIs (like sertraline, and fluoxetine), corticosteroids (including prednisone and dexamethasone), diuretics (such as furosemide and hydrochlorothiazide), ACE inhibitors (like enalapril and lisinopril), ARBs (such as losartan and valsartan), methotrexate, cyclosporine, lithium, aspirin, and other NSAIDs (like ibuprofen, naproxen).
An overdose of this medicine may cause nausea, vomiting, abdominal pain, drowsiness, hypotension, or hepatorenal damage. There is no specific antidote; treatment is symptomatic and supportive. Activated charcoal may be used within 1-2 hours of ingestion.
If you miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage nausea or dyspepsia, consider taking the medicine with meals or adjusting meal times relative to when you take the medication.
If experiencing mild headaches or dizziness, ensure adequate hydration by drinking sufficient water throughout the day.
This medication may affect your ability to drive or operate heavy machinery. Avoid driving if you feel dizzy or sleepy after taking this medicine.
This medicine is not recommended during pregnancy, particularly in the third trimester, and while breastfeeding unless advised by your doctor.
It is advised to consult your doctor before using this medicine during pregnancy and lactation.
Patients with mild to moderate hepatic impairment should use this medicine cautiously and at the lowest effective dose.
Caution is advised for patients with renal impairment; avoid using this medicine in cases of severe renal failure.
Maintain a balanced diet rich in vegetables, fruits, whole grains, and lean proteins to support overall health and potentially reduce inflammation associated with musculoskeletal conditions.
Engage in regular physical activity such as walking, swimming, or yoga to strengthen muscles around the joints and improve flexibility without excessive strain.
Consider incorporating omega-3 fatty acids found in fish like salmon or through supplements, as they can help reduce inflammation.
Maintain adequate hydration by drinking plenty of water throughout the day to help manage medication side effects such as dizziness or headaches.
Avoid foods that can aggravate inflammation such as refined sugars, dairy products high in fat, and red meat; opt instead for anti-inflammatory foods like turmeric, ginger, berries, nuts, and green leafy vegetables.
Practice stress-relief techniques such as meditation or deep-breathing exercises which can help manage pain perception related to chronic conditions like arthritis.
Frequently asked questions
No, Diclofenac + Paracetamol/Acetaminophen + Trypsin-Chymotrypsin is not addictive. However, it is advisable to use this medication strictly as prescribed by your doctor.
While this medication can help manage pain, it is not specifically indicated for migraines. You should always consult your doctor before using any medicine.
Weight gain is not a commonly reported side effect of Diclofenac + Paracetamol/Acetaminophen + Trypsin-Chymotrypsin. However, individual responses to medicine can vary.
It is generally recommended to avoid alcohol while taking this medicine as it may increase the risk of liver damage and gastrointestinal bleeding.
This medication should be used at the lowest effective dose for the shortest duration necessary due to potential risks. Long-term use requires medical supervision.
It is usually safe to stop taking this medicine suddenly; however, your symptoms may return. Always speak to your doctor before stopping any medication.
This medicine should not be used during the third trimester of pregnancy. If you are pregnant or planning to become pregnant, consult your doctor before starting this medication.
Diclofenac + Paracetamol/acetaminophen + Trypsin-chymotrypsin in other salts
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