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Diclofenac + Paracetamol/acetaminophen


Uses of Diclofenac + Paracetamol/acetaminophen

  • Diclofenac + Paracetamol is an anti-inflammatory, analgesic and antipyretic agent used to manage pain and inflammation in various conditions like headaches, nerve pain, aches and pains of cold and flu, toothaches, sprains and strains, muscular and traumatic pains, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, lower back pain, bursitis and tendinitis, and acute gout.
  • This combination is also used to manage post-operative pain.
  • It can also be used for menstrual pain.

Side effects of Diclofenac + Paracetamol/acetaminophen

  • Abdominal pain 
  • Diarrhoea 
  • Indigestion
  • Heartburn 
  • Nausea

How Diclofenac + Paracetamol/acetaminophen works

  • Diclofenac + Paracetamol is a pain reliever.
  • Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the production of certain chemicals in the body called prostaglandins. These are responsible for inflammation, pain, and fever. Diclofenac helps reduce pain, inflammation, and swelling by blocking their production.
  • Paracetamol is an analgesic and antipyretic agent. It inhibits prostaglandin synthesis in the brain to lower fever and reduce pain.

Certified content

Written By

Amit SharmaClinical Health & Medical Writer| 3 Years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 Years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Diclofenac + Paracetamol can be taken orally (tablet).

Age And Dose Restrictions

  • This combination is intended to be used by adults only. It is not recommended for children.


  • This combination is contraindicated in patients with a history of hypersensitivity to diclofenac or paracetamol, history of allergic reactions (bronchospasm, shock, rhinitis, urticaria) following the use of Aspirin or another NSAID, in the last three months of pregnancy, in patients with active stomach and/or duodenal ulceration or gastrointestinal bleeding, inflammatory intestinal disorders such as Crohn's disease or ulcerative colitis, and in patients with liver, heart, or kidney disorders.

Medications To Avoid With This Drug

  • Diclofenac + Paracetamol can interact with various medications. Therefore, it is important to inform your doctor about any medicines including over the counter medicines that you are currently taking. 

Overdose And Missed Dose

  • Overdose can cause lethargy, drowsiness, nausea, and vomiting. These symptoms need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
  • If you miss a dose of this combination, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management Of Side Effects

  • Take this combination with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • This combination can cause dizziness and drowsiness. It is not recommended to drive, operate machinery, or do other activities requiring mental alertness or coordination after this combination. 

Use In Pregnancy And Lactation

  • This combination is not recommended during the last three months of pregnancy. Caution is advised during the first six months of pregnancy and breastfeeding.

Caution In Other Conditions

  • Caution is advised in older adults and patients with heart conditions, active ulceration/bleeding, pre-existing asthma, aspirin-sensitive asthma, acute porphyria, peptic ulcers, hypertension and kidney and liver impairment.

Special Dietary And Lifestyle Recommendation

  • Avoid alcohol consumption, as it may increase the risk of liver toxicity and adverse side effects.
  • Take this combination only for the prescribed duration.
  • Maintain a healthy weight. Excess weight can contribute to joint pain and inflammation, so maintaining a healthy weight can reduce these issues.
  • Engage in regular, low-impact exercises such as walking, swimming, or cycling to improve flexibility and strengthen muscles.

Frequently asked questions

Yes, this combination is a painkiller that helps reduce mild to moderate pain associated with various musculoskeletal conditions, headache, toothache, menstrual pain and post-surgery pain.

This combination typically show their effects within 30 minutes to an hour after ingestion. However, individual responses may vary. 

No, this combination is not habit-forming and is generally safe when used as directed.

There is limited information on the effect of this medicine on fertility. It is recommended to aks your doctor for advice if you are pregnant or planning to become pregnant. 

This combination usually requires a prescription and is not available over the counter.

This combination may relieve pain for up to a few hours. However, the duration of effect of this medication can vary with the individual and the severity of the condition being treated.

This combination is not recommended for stomach pain. It is primarily used for musculoskeletal pain.

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