Serratiopeptidase
AntiinflammatoryUses of Serratiopeptidase
Serratiopeptidase is a proteolytic enzyme that may be prescribed as an adjunct to reduce swelling after surgery or injury; approved uses and supporting evidence vary.
It is commonly used for:
• Post-surgical swelling: May help reduce oedema after selected surgical or dental procedures when prescribed with standard care.
• Post-traumatic swelling: May be used as an adjunct for swelling after soft-tissue injury.
• Soft-tissue inflammation: Sometimes prescribed for short-term swelling and discomfort in selected inflammatory conditions.
• Dental swelling: May be used alongside definitive dental treatment to reduce post-procedure swelling.
• Sports injuries: Sometimes prescribed as supportive treatment for swelling after sprains or strains.
• Localised oedema: May be considered for selected cases of inflammatory swelling under medical supervision.
Side effects of Serratiopeptidase
The side effects of Serratiopeptidase are:
- Stomach
- Intestinal discomfort
- Nausea
- Vomiting
- Diarrhoea
How Serratiopeptidase works
- Serratiopeptidase is a proteolytic enzyme, meaning that it can break down certain proteins.
- It is proposed to act on protein-rich inflammatory material at sites of tissue injury and may influence substances involved in swelling.
- Its absorption, clinical effects, and exact anti-inflammatory mechanism after oral use are not fully established, and evidence for many promoted uses is limited.
- It should therefore be described as an adjunct that may help reduce swelling in selected situations rather than as a medicine proven to relieve pain or accelerate healing.
Certified content
Written By
MBBS
Reviewed By
MBBS, DNB (OBGY)
Expert Advice
Dosage Forms Available
- Serratiopeptidase can be taken orally (tablet, capsule and powder).
Age And Dose Restrictions
- Serratiopeptidase is intended to be used by adults only. It is not recommended for children.
Contraindications
- It is contraindicated in patients with a history of hypersensitivity to Serratiopeptidase. It is also contraindicated in patients with gastric ulcers in the upper digestive tract.
Other Medications To Avoid With This Medicine
- Avoid taking anticoagulants and antiplatelet medicines such as warfarin, clopidogrel, or aspirin. The concomitant use may increase the risk of bleeding or bruising.
Overdose And Missed Dose
- Taking more than the recommended dose may cause nausea, vomiting, stomach discomfort, and in rare cases, blood may appear in phlegm or sputum due to the enzyme's protein-dissolving activity. If you experience any of these symptoms after taking more than the prescribed dose, contact your doctor or go to the nearest hospital immediately. Strict adherence to the prescribed dose is essential.
- If you miss a dose of Serratiopeptidase, take it as soon as you remember. If it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.
Management Of Side Effects
- Take Serratiopeptidase with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.
Use In Driving And Operating Machinery
- This medication does not affect your ability to drive or use machines. If it makes you feel dizzy or tired, do not drive or use machines and contact your doctor immediately.
Use In Pregnancy And Lactation
- Consult your doctor if you are pregnant or breastfeeding.
Caution In Other Conditions
- Caution is advised in patients with blood coagulation disorders and kidney and liver impairment.
Special Dietary And Lifestyle Recommendation
- Serratiopeptidase might increase bleeding during and after surgery. Thus, it should be discontinued at least 2 weeks before your surgery is scheduled.
- Avoid taking garlic, fish oil and turmeric with Serratiopeptidase, as it may increase the risk of bleeding or bruising.
- Continue taking Serratiopeptidase for as long as your doctor recommends.
- Avoid alcohol consumption, as it may increase the risk of gastrointestinal side effects.
Frequently asked questions
1. Can Serratiopeptidase be used for knee pain?
This medication may be considered for knee pain due to its anti-inflammatory properties, which can potentially reduce swelling and discomfort. However, do not take it until prescribed by a doctor.
2. Is Serratiopeptidase a painkiller?
No, this medication is not a painkiller. It helps reduce inflammation in various conditions.
3. How long does Serratiopeptidase take to provide relief?
You may experience relief from inflammation-related symptoms within a few days. However, the individual response may vary. Continue taking the medicine as prescribed by your doctor.
4. Is Serratiopeptidase a habit-forming medicine?
This medication is not habit-forming and is generally safe when used as directed.
5. Is Serratiopeptidase available over the counter, or do I need a prescription?
This medication usually requires a prescription but is also available over the counter as a supplement. Consult your doctor about the appropriate usage for your condition.
6. What is Serratiopeptidase used for?
Serratiopeptidase is an enzyme used to reduce pain, swelling, and inflammation. It is commonly given after dental or oral surgery, tooth extraction, jaw injuries, and infections to help reduce swelling and speed up healing. It is also used for pain and swelling caused by conditions such as back pain, osteoarthritis, and rheumatoid arthritis, helping improve comfort and recovery.
Serratiopeptidase in other salts
List of medicines for Serratiopeptidase
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