Caffeine + Ergotamine + Paracetamol/Acetaminophen + Prochlorperazine primarily manages acute migraine attacks and prevents recurring migraines in adults and belongs to the group of analgesics and antiemetics.
Some common side effects are:
Nausea
Dizziness
Restlessness
Muscle aches
Dry mouth
Caffeine + Ergotamine + Paracetamol/Acetaminophen + Prochlorperazine is a multi-action migraine management medication.
Ergotamine, an ergot alkaloid, constricts dilated blood vessels in the head during migraines, thus easing the throbbing pain.
Caffeine aids in better absorption of ergotamine and further helps to constrict blood vessels.
Paracetamol/Acetaminophen is a pain reliever that inhibits the release of prostaglandins, substances in the brain that can lead to pain.
Prochlorperazine is an antiemetic. It prevents feelings of nausea and vomiting by blocking dopamine receptors, which are responsible for triggering these symptoms.
Doctor of Medicine
BMS, FMC, MD Resident
Caffeine + Ergotamine + Paracetamol/Acetaminophen + Prochlorperazine is available for use via oral route in the form of tablets.
This medicine is indicated for adults only.
It should not be used by children or adolescents under 18 years of age.
This combination medicine is contraindicated in patients with severe liver or kidney disease, coronary artery disease, uncontrolled hypertension, stroke, peripheral vascular disease.
It should not be used by people who have sepsis or severe infections.
Individuals allergic to any of the ingredients in this combination should refrain from using it.
This combination may interact with other migraine medications (such as sumatriptan), anticoagulants (like warfarin), and sedatives (such as benzodiazepines).
An overdose of this medication may result in excessive drowsiness, confusion, tremors, muscle stiffness, and rapid heartbeat. If you observe these symptoms, seek emergency medical attention immediately.
Should you miss a dose of this medicine take as soon as you remember. However, if it is close to the time for your next dose, skip the missed one and continue with your regular dosing schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If this medication causes dry mouth, try frequent mouth rinses, good oral hygiene, and sugarless candy or gum.
If you experience dizziness or drowsiness, avoid strenuous activities and rest as much as possible.
This combination medicine may cause dizziness or drowsiness. Therefore, it is recommended to avoid driving or operating heavy machinery until you know how this medicine affects you.
Pregnant or breastfeeding women should not use this medicine without consulting their doctor.
Patients with severe cardiovascular conditions like coronary artery disease, uncontrolled hypertension, stroke, peripheral vascular disease need to exercise caution when taking this medication.
Regularly monitoring your blood pressure can help manage underlying conditions like hypertension that often accompany migraines.
Limiting caffeinated beverages may help control migraine triggers.
Ensure adequate hydration throughout the day as dehydration can trigger migraines.
Regular sleep schedule can help prevent migraines.
Stress management techniques such as yoga, meditation can also help manage migraine outbreaks.
Frequently asked questions
No, this medicine is not addictive. However, it is necessary to take it under the supervision of a doctor.
Mood swings are not a common side effect of this medicine. However, if you experience any changes in mood after taking this medication, consult your doctor.
There are no food restrictions reported with this medicine but it is advised to take it as per your doctor’s instructions.
There is no scientific data suggesting that this medicine affects menstruation. If you notice any changes in your menstrual cycle after taking it, consult your doctor.
The active ingredients in this medication are all synthetically produced and do not contain any animal-derived ingredients. However, it is always good to consult your doctor or pharmacist for further details.
The half-life of a medicine is the time it takes for half the medicine to be eliminated from the body. The half-lives of the salts in this medicine vary, with caffeine having a half-life of 3-7 hours, ergotamine 2 hours, paracetamol/acetaminophen 1-4 hours, and prochlorperazine 9-24 hours.
Weight gain is not a common side effect of this medicine. However, if you notice any significant changes in your weight after taking it, please consult your doctor.
Caffeine + Ergotamine + Paracetamol/acetaminophen + Prochlorperazine in other salts
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