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Paracetamol/acetaminophen + Tapentadol

Uses of Paracetamol/acetaminophen + Tapentadol

  • Paracetamol/Acetaminophen + Tapentadol is primarily used to manage moderate to severe pain in adults and belongs to the group of analgesics.

Side effects of Paracetamol/acetaminophen + Tapentadol

  • Nausea

  • Vomiting

  • Dizziness

  • Sleepiness

  • Constipation

How Paracetamol/acetaminophen + Tapentadol works

  • Paracetamol, also known as Acetaminophen, is thought to work by reducing the production of certain chemicals in the brain called prostaglandins, which cause pain and fever. This leads to a decrease in how much pain you perceive or feel.

  • Tapentadol is an opioid that works by attaching to specific proteins called mu-opioid receptors in your brain and spinal cord. By doing this, it inhibits the transmission of pain signals to the brain.

  • Together, these two components work in different ways to alleviate your pain more effectively than either medicine would do by itself.

Certified content

Written By

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Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Reviewed By

Dr. Michelle Frank
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Expert Advice

Dosage Forms Available

  • The combination of Paracetamol/Acetaminophen + Tapentadol is available in the form of oral tablets.

Age and Dose Restrictions

  • Paracetamol/Acetaminophen + Tapentadol is suitable for adults and children aged 16 years and above.

Contraindications

  • Paracetamol/Acetaminophen + Tapentadol should not be used by patients who are hypersensitive to either Paracetamol/Acetaminophen or Tapentadol.

  • It is contraindicated in patients with significant respiratory depression, acute or severe bronchial asthma and paralytic ileus.

Other Medications to Avoid

  • Paracetamol/Acetaminophen + Tapentadol may interact with central nervous system depressants (such as diazepam and pentobarbital), serotonin-modulating medications (such as vilazodone and trazodone) and anticoagulants (such as warfarin).

Overdose and Missed Dose

  • If you suspect an overdose of Paracetamol/Acetaminophen + Tapentadol, seek immediate medical attention. Overdose may cause serious complications like liver damage or respiratory depression.

  • If you miss a dose of Paracetamol/Acetaminophen + Tapentadol, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your normal dosing schedule. Do not double up the dose.

Management of Side Effects

Most side effects of Paracetamol/Acetaminophen + Tapentadol are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage nausea or vomiting, try taking this medicine with food.

  • To manage constipation, increase fibre in your diet, drink plenty of water and engage in regular physical activity.

Use in Driving and Operating Machinery

  • Paracetamol/Acetaminophen + Tapentadol may cause dizziness or sleepiness. It is advisable not to drive or operate heavy machinery until you know how this combination affects you.

Use in Pregnancy and Lactation

  • Paracetamol/Acetaminophen + Tapentadol should only be used during pregnancy or lactation if the potential benefit justifies the potential risk to the baby. Always consult your doctor before use.

Caution in Other Conditions

  • Patients with liver or kidney impairment should exercise caution when taking Paracetamol/Acetaminophen + Tapentadol.

  • Caution is also advised for patients with respiratory condition known as sleep apnea.

Special Dietary and Lifestyle Recommendations

  • To manage pain effectively, try to maintain a balanced diet and include foods rich in vitamin D and calcium which are essential for bone health.

  • Regular physical activity can also help improve overall health and reduce inflammation.

Frequently asked questions

No, Paracetamol/Acetaminophen + Tapentadol is not a steroid. It is a combination of analgesics (pain relievers) used to manage moderate to severe pain.

Yes, one of the common side effects of Paracetamol/Acetaminophen + Tapentadol is drowsiness or sleepiness. Patients are advised to avoid tasks requiring alertness, such as driving until they know how the medication affects them.

Paracetamol/Acetaminophen + Tapentadol is not typically associated with changes in fertility. However, if you have specific concerns, it's best to consult a doctor.

Paracetamol/Acetaminophen + Tapentadol should be taken for the duration and as per the dosage recommended by your doctor.

Paracetamol (acetaminophen) + tapentadol is associated with a risk of dependency due to the opioid nature of tapentadol. Prolonged use should be monitored by a healthcare professional to avoid tolerance and dependence.

No natural substitute provides the same level of pain control as Paracetamol/Acetaminophen + Tapentadol. Always consult your doctor before starting any new medicine, including herbal or natural remedies.

Paracetamol/Acetaminophen + Tapentadol is not associated with effects on menstruation. If you notice any changes in your menstruation while taking this medicine, please consult your doctor.

Terms & Conditions


Paracetamol/acetaminophen + Tapentadol in other salts

ACECLOFENAC + PARACETAMOL/ACETAMINOPHENACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHENIBUPROFEN + PARACETAMOL/ACETAMINOPHENNIMESULIDE + PARACETAMOL/ACETAMINOPHENTAPENTADOLACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + RABEPRAZOLEDEXTROPROPOXYPHENE + PARACETAMOL/ACETAMINOPHENLORNOXICAM + PARACETAMOL/ACETAMINOPHENNIMESULIDE + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDEXTROPROPOXYPHENE + DICYCLOMINE + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHEN + TRAMADOLDEXIBUPROFEN + PARACETAMOL/ACETAMINOPHENDICYCLOMINE + PARACETAMOL/ACETAMINOPHEN + TRAMADOLDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRYPSIN-CHYMOTRYPSINCAFFEINE + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDEPARACETAMOL/ACETAMINOPHEN + RACEMETHIONINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECPM + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECAMYLOFIN + PARACETAMOL/ACETAMINOPHENCHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATEPARACETAMOL/ACETAMINOPHEN + PROMETHAZINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDOMPERIDONE + PARACETAMOL/ACETAMINOPHENCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHENMETOCLOPRAMIDE + PARACETAMOL/ACETAMINOPHENDOMPERIDONE + FLUNARIZINE + PARACETAMOL/ACETAMINOPHENONDANSETRON + PARACETAMOL/ACETAMINOPHENLEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEBROMHEXINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEIBUPROFEN + MAGNESIUM TRISILICATE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TIZANIDINEPARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRAMADOLCHLORZOXAZONE + PARACETAMOL/ACETAMINOPHENCAFFEINE + IBUPROFEN + PARACETAMOL/ACETAMINOPHENDOMPERIDONE + PARACETAMOL/ACETAMINOPHEN + TRAMADOLDICYCLOMINE + PAMABROM + PARACETAMOL/ACETAMINOPHENIBUPROFEN + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASECAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + DIPHENHYDRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDICLOFENAC + METHOCARBAMOL + PARACETAMOL/ACETAMINOPHENHYOSCINE + PARACETAMOL/ACETAMINOPHENETORICOXIB + PARACETAMOL/ACETAMINOPHENCETIRIZINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRYPSIN-CHYMOTRYPSINFEXOFENADINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECODEINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHENDICLOFENAC + DICYCLOMINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENAZONEBROMHEXINE + CPM + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDEXTROPROPOXYPHENE + NIMESULIDE + PARACETAMOL/ACETAMINOPHENDROTAVERINE + PARACETAMOL/ACETAMINOPHENDICYCLOMINE + MEFENAMIC ACID + PARACETAMOL/ACETAMINOPHENETODOLAC + PARACETAMOL/ACETAMINOPHENLORNOXICAM + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TIZANIDINEDEXKETOPROFEN + PARACETAMOL/ACETAMINOPHENBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORZOXAZONE + NIMESULIDE + PARACETAMOL/ACETAMINOPHENCHLORZOXAZONE + DICLOFENAC SODIUM + PARACETAMOL/ACETAMINOPHENCAFFEINE + CETIRIZINE + NIMESULIDE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORZOXAZONE + IBUPROFEN + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHEN + TOLPERISONECAFFEINE + CETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDEXTROPROPOXYPHENE + DICLOFENAC + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHEN + PROCHLORPERAZINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + ERGOTAMINE + PARACETAMOL/ACETAMINOPHEN + PROCHLORPERAZINEPARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEAMBROXOL + CETIRIZINE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN
Available medicines for PARACETAMOL/ACETAMINOPHEN + TAPENTADOL
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Acutap P 50/325 MG Tablet 10
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Proxyvon Forte 50/325 MG Tablet 10
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