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Caffeine + Paracetamol/acetaminophen + Phenylephrine

Uses of Caffeine + Paracetamol/acetaminophen + Phenylephrine

  • Caffeine + Paracetamol/Acetaminophen + Phenylephrine is primarily used for the temporary relief of symptoms associated with the common cold, flu, allergies, and other respiratory illnesses. This combination belongs to the group of over-the-counter cold and flu medications.

  • It can also be used for sinusitis and bronchitis relief.

Side effects of Caffeine + Paracetamol/acetaminophen + Phenylephrine

  • Anxiety

  • Dizziness

  • Insomnia

  • Upset stomach

  • Irregular or fast heartbeat

How Caffeine + Paracetamol/acetaminophen + Phenylephrine works

  • Paracetamol/Acetaminophen is an analgesic and antipyretic. It reduces pain and fever by blocking the production of chemicals called prostaglandins in the brain, which trigger inflammation and increase body temperature.

  • Caffeine is a central nervous system stimulant. It enhances the effectiveness of paracetamol in relieving pain, and also increases wakefulness and alertness, helping to counter feelings of fatigue or drowsiness.

  • Phenylephrine is a nasal decongestant. It alleviates congestion by causing the blood vessels in the nasal passages to narrow, reducing swelling, and making it easier to breathe.

Certified content

Written By

docImg
Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Caffeine + Paracetamol/Acetaminophen + Phenylephrine is available for oral administration as tablets, capsules, effervescent tablets, powders, liquids/suspensions, chewable tablets, and orally disintegrating tablets/strips.

Age and Dose Restrictions

  • This medicine is meant for adults and children above 12 years of age.

Contraindications

  • This medicine is contraindicated in patients with severe liver or kidney impairment. It is also contraindicated in patients with severe hypertension or coronary artery disease. Patients who have taken MAO inhibitors in the past 14 days should not use this medicine.

Other Medications to Avoid

  • Caffeine + Paracetamol/Acetaminophen + Phenylephrine may interact with other decongestants, antihistamines (such as diphenhydramine and cetirizine), antidepressants (like duloxetine, fluoxetine, and sertraline), and blood pressure medications (including beta-blockers like atenolol and alpha-blockers like prazosin).

Overdose and Missed Dose

  • An overdose of this medication can lead to symptoms such as nausea, vomiting, increased heart rate, confusion, liver injury, or even more severe conditions like seizures. Urgent medical attention is required in case of overdose.

  • If you miss a dose of this medicine, take it as soon as you remember unless it is nearly time for your next dose. Do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For symptoms like nervousness or insomnia caused by caffeine, consider taking the medication earlier in the day.

  • In case of dry mouth or dizziness, ensure adequate hydration by drinking plenty of water.

Use in Driving and Operating Machinery

  • This medicine may impair your ability to drive or operate heavy machinery especially if you experience side effects such as dizziness or insomnia.

Use in Pregnancy and Lactation

  • It is advised to consult a doctor before using Caffeine + Paracetamol/Acetaminophen + Phenylephrine during pregnancy or lactation. The safety of this medication for use during these conditions has not been established.

Caution in Other Conditions

  • Caution is advised when using this medicine in patients with liver disease, heart disease, diabetes, glaucoma, or an overactive thyroid due to the potential risks associated with each ingredient affecting these conditions.

Special Dietary and Lifestyle Recommendations

  • Considering that Caffeine + Paracetamol/Acetaminophen + Phenylephrine is used to manage symptoms related to colds and allergies, maintaining a well-balanced diet rich in vitamins and minerals can support immune function.

  • Staying hydrated can help alleviate congestion and throat discomfort.

  • Regular rest during illness recovery periods can aid in faster healing while reducing reliance on medications for symptom management.

Frequently asked questions

No, this combination medicine does not contain any steroids. It consists of a central nervous system stimulant (caffeine), an analgesic and antipyretic (paracetamol), and a nasal decongestant (phenylephrine).

No, Caffeine + Paracetamol/Acetaminophen + Phenylephrine is not designed or approved for weight loss. It is a combination medication used primarily to relieve symptoms associated with the common cold, flu, allergies, sinusitis, bronchitis, or other upper respiratory tract infections.

Yes, one of the active ingredients in this combination, caffeine, is known as a stimulant that promotes wakefulness and mental alertness. However, this effect can vary from person to person.

There is no specific restriction on exercise while taking this medicine. However, if you feel dizzy or experience any other side effects that may affect your ability to exercise safely, you should stop exercising and consult your doctor.

The formulation of this medication varies by manufacturer and product. Some may contain ingredients derived from animal sources. You should check the ingredient list on the packaging or consult your pharmacist for more information about the specific product.

Some formulations of this medicine may contain lactose. If you are lactose intolerant, please check the ingredient list or consult your doctor before taking this medication.

This combination is not known to be habit-forming when used as directed by your doctor. However, regular use of caffeine, one of the ingredients in this medication, can lead to dependence and withdrawal symptoms.

Terms & Conditions


Caffeine + Paracetamol/acetaminophen + Phenylephrine in other salts

ACECLOFENAC + PARACETAMOL/ACETAMINOPHENACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHENIBUPROFEN + PARACETAMOL/ACETAMINOPHENNIMESULIDE + PARACETAMOL/ACETAMINOPHENCETIRIZINE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINEPARACETAMOL + CAFFEINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINE HYDROCHLORIDEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + RABEPRAZOLECHLORPHENIRAMINE + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINEDEXTROPROPOXYPHENE + PARACETAMOL/ACETAMINOPHENCPM + DEXTROMETHORPHAN + PHENYLEPHRINELORNOXICAM + PARACETAMOL/ACETAMINOPHENNIMESULIDE + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDEXTROPROPOXYPHENE + DICYCLOMINE + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHEN + TRAMADOLDEXIBUPROFEN + PARACETAMOL/ACETAMINOPHENDICYCLOMINE + PARACETAMOL/ACETAMINOPHEN + TRAMADOLDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRYPSIN-CHYMOTRYPSINCHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECAFFEINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEBECLOMETHASONE DIPROPIONATE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINECALCIUM DOBESILATE + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINE + TROXERUTIN + ZINC OXIDEPHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDEPARACETAMOL/ACETAMINOPHEN + RACEMETHIONINECARBOXY METHYL CELLULOSE + NAPHAZOLINE + PHENYLEPHRINENAPHAZOLINE + PHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECPM + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORBUTOL + PHENYLEPHRINE + TROPICAMIDECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE + DEXTROMETHORPHAN + MENTHOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINEBROMHEXINE + GUAIFENESIN + PHENYLEPHRINEBROMHEXINE + PHENYLEPHRINE + SALBUTAMOLBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEPHENYLEPHRINE + TROPICAMIDECAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECAMYLOFIN + PARACETAMOL/ACETAMINOPHENCHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATEPARACETAMOL/ACETAMINOPHEN + PROMETHAZINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDEDOMPERIDONE + PARACETAMOL/ACETAMINOPHENCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHENMETOCLOPRAMIDE + PARACETAMOL/ACETAMINOPHENDOMPERIDONE + FLUNARIZINE + PARACETAMOL/ACETAMINOPHENONDANSETRON + PARACETAMOL/ACETAMINOPHENAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PHENYLEPHRINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINECHLORPHENIRAMINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINEBROMHEXINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + GUAIFENESIN + PHENYLEPHRINEDEXTROMETHORPHAN + PHENYLEPHRINE + TRIPROLIDINEAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + MENTHOL + PHENYLEPHRINELEVOCETIRIZINE + PHENYLEPHRINEAMBROXOL + GUAIFENESIN + LEVOCETIRIZINE + PHENYLEPHRINEIBUPROFEN + MAGNESIUM TRISILICATE + PARACETAMOL/ACETAMINOPHENBROMHEXINE + DEXTROMETHORPHAN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + MENTHOL + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESIN + PHENYLEPHRINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TIZANIDINEPARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRAMADOLCHLORZOXAZONE + PARACETAMOL/ACETAMINOPHENCAFFEINE + IBUPROFEN + PARACETAMOL/ACETAMINOPHENDOMPERIDONE + PARACETAMOL/ACETAMINOPHEN + TRAMADOLPARACETAMOL/ACETAMINOPHEN + TAPENTADOLDICYCLOMINE + PAMABROM + PARACETAMOL/ACETAMINOPHENIBUPROFEN + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASECETIRIZINE + PHENYLEPHRINECAFFEINE + DIPHENHYDRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEASPIRIN + CAFFEINEDICLOFENAC + METHOCARBAMOL + PARACETAMOL/ACETAMINOPHENHYOSCINE + PARACETAMOL/ACETAMINOPHENETORICOXIB + PARACETAMOL/ACETAMINOPHENCETIRIZINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRYPSIN-CHYMOTRYPSINFEXOFENADINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECODEINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHENDICLOFENAC + DICYCLOMINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENAZONEBROMHEXINE + CPM + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDEXTROPROPOXYPHENE + NIMESULIDE + PARACETAMOL/ACETAMINOPHENDROTAVERINE + PARACETAMOL/ACETAMINOPHENDICYCLOMINE + MEFENAMIC ACID + PARACETAMOL/ACETAMINOPHENETODOLAC + PARACETAMOL/ACETAMINOPHENLORNOXICAM + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TIZANIDINEDEXKETOPROFEN + PARACETAMOL/ACETAMINOPHENBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORZOXAZONE + NIMESULIDE + PARACETAMOL/ACETAMINOPHENAMBROXOL + LEVOCETIRIZINE + PHENYLEPHRINECHLORZOXAZONE + DICLOFENAC SODIUM + PARACETAMOL/ACETAMINOPHENCAFFEINE + CETIRIZINE + NIMESULIDE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORZOXAZONE + IBUPROFEN + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHEN + TOLPERISONECAFFEINE + CETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDEXTROPROPOXYPHENE + DICLOFENAC + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHEN + PROCHLORPERAZINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + ERGOTAMINE + PARACETAMOL/ACETAMINOPHEN + PROCHLORPERAZINELEVOCETIRIZINE + NIMESULIDE + PHENYLEPHRINEPARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEAMBROXOL + CETIRIZINE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CETIRIZINE + NIMESULIDE + PHENYLEPHRINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN
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