Home/Drugs By Ailments / Dextropropoxyphene + Nimesulide + Paracetamol/acetaminophen

Dextropropoxyphene + Nimesulide + Paracetamol/acetaminophen

Uses of Dextropropoxyphene + Nimesulide + Paracetamol/acetaminophen

  • Dextropropoxyphene + Nimesulide + Paracetamol/Acetaminophen is primarily used for the short-term management of acute pain such as post-operative pain, acute musculoskeletal pain and other short-term painful conditions. It belongs to a group of medicines known as analgesics.

Side effects of Dextropropoxyphene + Nimesulide + Paracetamol/acetaminophen

  • Nausea

  • Vomiting

  • Constipation

  • Dizziness

  • Drowsiness

How Dextropropoxyphene + Nimesulide + Paracetamol/acetaminophen works

  • Dextropropoxyphene + Nimesulide + Paracetamol/Acetaminophen is a combination analgesic medication.

  • Dextropropoxyphene is an opioid. It works by activating the opioid receptors in the brain and spinal cord, which changes your body's response to and perception of pain.

  • Nimesulide is a non-steroidal anti-inflammatory medicine (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Specifically, it inhibits an enzyme known as cyclooxygenase (COX), which is involved in the production of prostaglandins, substances that mediate inflammation.

  • Paracetamol/Acetaminophen is a non-opioid analgesic and antipyretic. It works by inhibiting the production of prostaglandins in the brain, which are responsible for sensations of pain and fever. However, its exact mechanism of action is not fully understood.

Certified content

Written By

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Ashmita BorgohainMedical Content Writer & Editor| 12 years

MSc (Applied Genetics)

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Dextropropoxyphene + Nimesulide + Paracetamol/Acetaminophen is available for oral administration in the form of tablets.

Age and Dose Restrictions

  • This combination medicine is suitable for adults and children above 12 years of age.

Contraindications

  • This medicine is contraindicated in patients with hypersensitivity to any of the active ingredients: Dextropropoxyphene, Nimesulide, or Paracetamol/Acetaminophen.

  • It is also contraindicated in patients with severe respiratory depression, acute or severe bronchial asthma, paralytic ileus, severe hepatic impairment, severe renal impairment, and active peptic ulcer or gastrointestinal bleeding.

Other Medications to Avoid

  • This combination may interact with benzodiazepines (such as diazepam and alprazolam), other opioids (like morphine and fentanyl), antipsychotics (including clozapine and olanzapine), and CYP2D6 and CYP3A4 inhibitors (such as fluoxetine and ketoconazole).

Overdose and Missed Dose

  • An overdose of this medication may cause respiratory depression, extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, hypotension, bradycardia, liver damage, renal failure, coma, and even death. Immediate medical attention is needed.

  • If you forget to take your prescribed dose of this medicine, take it as soon as you remember. However if it is near the time for your next dose then skip the missed dose. Do not double up to make up for a missed dose.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of fluids may help with some side effects like constipation and dry mouth.

  • Taking this medicine after a meal may help reduce gastrointestinal side effects like nausea and abdominal pain.

Use in Driving and Operating Machinery

  • This medication may cause dizziness, drowsiness or impair your alertness. Avoid driving or operating heavy machinery if you experience these effects.

Use in Pregnancy and Lactation

  • The use of Dextropropoxyphene + Nimesulide + Paracetamol/Acetaminophen during pregnancy and breastfeeding is not recommended unless prescribed by a doctor. Always consult your doctor before starting any medication during pregnancy or lactation.

Caution in Other Conditions

  • Patients with liver or kidney disease, respiratory conditions, history of medication abuse or addiction, and patients with a history of gastrointestinal disorders should exercise caution when taking this medication.

Special Dietary and Lifestyle Recommendations

  • Ensure adequate fluid intake to prevent dehydration which may worsen constipation.

  • Regular mild to moderate physical activity can help improve overall health and wellbeing.

  • Limit or avoid alcohol consumption when taking this medicine as it can increase the risk of liver damage and gastrointestinal bleeding.

Frequently asked questions

No, Dextropropoxyphene + Nimesulide + Paracetamol/Acetaminophen is not a steroid. The combination is composed of an opioid pain reliever, a non-steroidal anti-inflammatory drug (NSAID), and a non-opioid pain reliever and fever reducer.

Yes, this combination can cause side effects such as drowsiness and changes in mood, which might affect your sleep. If you experience persistent sleep disturbance while taking this medication, you should consult your doctor.

These medications are not known to directly affect fertility. However, if you are planning to conceive or are already pregnant, you should always consult your doctor before starting any new medication.

This medicine should not be taken if you have severe bronchial asthma as it can cause respiratory depression. Always consult your doctor before starting any new medication.

This medication is generally used for short-term management of acute pain, usually not more than 10 days. It is advisable to use the lowest effective dose for the shortest duration as recommended by your doctor.

The time taken for these medications to work may vary depending on the severity and type of pain. Your doctor will guide you regarding the expected time frame.

This medication can be taken at any time of the day, with or without food. However, doses should be spaced evenly throughout the day, as advised by your doctor.

Terms & Conditions


Dextropropoxyphene + Nimesulide + Paracetamol/acetaminophen in other salts

ACECLOFENAC + PARACETAMOL/ACETAMINOPHENACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHENIBUPROFEN + PARACETAMOL/ACETAMINOPHENNIMESULIDE + PARACETAMOL/ACETAMINOPHENNIMESULIDEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + RABEPRAZOLENIMESULIDE + TIZANIDINEDEXTROPROPOXYPHENE + PARACETAMOL/ACETAMINOPHENDICLOFENAC + NIMESULIDELORNOXICAM + PARACETAMOL/ACETAMINOPHENNIMESULIDE + SERRATIOPEPTIDASENIMESULIDE + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDEXTROPROPOXYPHENE + DICYCLOMINE + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHEN + TRAMADOLDEXIBUPROFEN + PARACETAMOL/ACETAMINOPHENDICYCLOMINE + PARACETAMOL/ACETAMINOPHEN + TRAMADOLDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRYPSIN-CHYMOTRYPSINCAFFEINE + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDICYCLOMINE + NIMESULIDECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDEPARACETAMOL/ACETAMINOPHEN + RACEMETHIONINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECPM + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECAMYLOFIN + PARACETAMOL/ACETAMINOPHENCHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATEPARACETAMOL/ACETAMINOPHEN + PROMETHAZINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDOMPERIDONE + PARACETAMOL/ACETAMINOPHENCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHENMETOCLOPRAMIDE + PARACETAMOL/ACETAMINOPHENDOMPERIDONE + FLUNARIZINE + PARACETAMOL/ACETAMINOPHENONDANSETRON + PARACETAMOL/ACETAMINOPHENLEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEBROMHEXINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEIBUPROFEN + MAGNESIUM TRISILICATE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TIZANIDINEPARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRAMADOLCHLORZOXAZONE + PARACETAMOL/ACETAMINOPHENCAFFEINE + IBUPROFEN + PARACETAMOL/ACETAMINOPHENDOMPERIDONE + PARACETAMOL/ACETAMINOPHEN + TRAMADOLPARACETAMOL/ACETAMINOPHEN + TAPENTADOLDICYCLOMINE + PAMABROM + PARACETAMOL/ACETAMINOPHENIBUPROFEN + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASECAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + DIPHENHYDRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAMYLOFIN + NIMESULIDEDICLOFENAC + METHOCARBAMOL + PARACETAMOL/ACETAMINOPHENHYOSCINE + PARACETAMOL/ACETAMINOPHENETORICOXIB + PARACETAMOL/ACETAMINOPHENCETIRIZINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRYPSIN-CHYMOTRYPSINFEXOFENADINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECODEINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHENDICLOFENAC + DICYCLOMINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENAZONEBROMHEXINE + CPM + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDROTAVERINE + PARACETAMOL/ACETAMINOPHENDICYCLOMINE + MEFENAMIC ACID + PARACETAMOL/ACETAMINOPHENETODOLAC + PARACETAMOL/ACETAMINOPHENLORNOXICAM + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TIZANIDINEDEXKETOPROFEN + PARACETAMOL/ACETAMINOPHENBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORZOXAZONE + NIMESULIDE + PARACETAMOL/ACETAMINOPHENCHLORZOXAZONE + DICLOFENAC SODIUM + PARACETAMOL/ACETAMINOPHENCAFFEINE + CETIRIZINE + NIMESULIDE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORZOXAZONE + IBUPROFEN + PARACETAMOL/ACETAMINOPHENCHLORZOXAZONE + NIMESULIDEPARACETAMOL/ACETAMINOPHEN + TOLPERISONECAFFEINE + CETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDEXTROPROPOXYPHENE + DICLOFENAC + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHEN + PROCHLORPERAZINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + ERGOTAMINE + PARACETAMOL/ACETAMINOPHEN + PROCHLORPERAZINELEVOCETIRIZINE + NIMESULIDE + PHENYLEPHRINEPARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEAMBROXOL + CETIRIZINE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CETIRIZINE + NIMESULIDE + PHENYLEPHRINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN
Available medicines for DEXTROPROPOXYPHENE + NIMESULIDE + PARACETAMOL/ACETAMINOPHEN
Orthodex 100/325/32.5 MG Tablet 12
Orthodex 100/325/32.5 MG Tablet 12
Psychotropics India Ltd
Pack of 12 Units
₹36.90
MRP ₹45.00
18.00% OFF
Oxymark 100/400/32.5 MG Tablet 10
Oxymark 100/400/32.5 MG Tablet 10
Unimarck Healthcare Ltd
Pack of 10 Units
₹35.15
MRP ₹42.86
18.00% OFF
Nimodex 100/400/32.5 MG Tablet 10
Nimodex 100/400/32.5 MG Tablet 10
Psychotropics India Ltd
Pack of 10 Units
₹36.90
MRP ₹45.00
18.00% OFF
Deepex 100/400/32.5 MG Tablet 10
Deepex 100/400/32.5 MG Tablet 10
Organic Laboratories
Pack of 10 Units
₹78.06
MRP ₹95.20
18.00% OFF

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