Home/Drugs By Ailments / Diclofenac + Paracetamol/Acetaminophen + Tizanidine

Diclofenac + Paracetamol/Acetaminophen + Tizanidine

Uses of Diclofenac + Paracetamol/Acetaminophen + Tizanidine

Diclofenac + Paracetamol + Tizanidine is a combination medicine used to relieve pain and muscle spasm associated with musculoskeletal conditions.
This combination is commonly used for:
• Acute back pain: Relieves pain and muscle spasm associated with lower back conditions.
• Muscle spasm: Eases tightness and spasm in skeletal muscles caused by injury or musculoskeletal disorders.
• Osteoarthritis and joint pain: Reduces pain and inflammation associated with joint conditions.
• Post-injury or post-surgical pain: Helps manage pain and muscle tightness following minor injuries or procedures.
• Cervical spondylosis: Relieves neck pain and associated muscle spasm.

Side effects of Diclofenac + Paracetamol/Acetaminophen + Tizanidine

  • Nausea
  • Vomiting
  • Dizziness
  • Headache
  • Skin rash

How Diclofenac + Paracetamol/Acetaminophen + Tizanidine works

Diclofenac + Paracetamol + Tizanidine works through three separate mechanisms to relieve pain, inflammation, and muscle spasm together.
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). It blocks enzymes called cyclooxygenases (COX), which reduces the production of prostaglandins, chemicals responsible for causing pain, inflammation, and swelling.
Pracetamol is a pain reliever and fever reducer. It acts on the brain's pain and temperature-regulating centres to reduce the perception of pain and lower fever.
Tizanidine is a muscle relaxant. It acts on the central nervous system to reduce the excessive nerve signals that cause muscles to tighten, easing muscle spasm and stiffness.
Together, these three ingredients relieve pain and inflammation whilst directly easing muscle spasm, making the combination effective for musculoskeletal pain accompanied by muscle tightness.

Certified content

Written By

docImg
Dr. Michelle FrankMedical Content Writer| 10 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi RoshaMedical Content Writer| 10 years

BAMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Diclofenac + Paracetamol / Acetaminophen + Tizanidine is available in oral tablet form. The combination is meant to be taken via the oral route.

Age and Dose Restrictions

  • This medication is suitable for adults and children above the age of 12 years.

Contraindications

  • This medicine should not be used by patients with hypersensitivity to any of its components.
  • Individuals with active gastrointestinal bleeding or peptic ulcer disease are advised not to take this medicine.
  • It is also contraindicated in people with severe liver or kidney impairment, a history of asthma, urticaria, or allergic reactions to aspirin or other nonsteroidal anti-inflammatory medicines.

Other Medications to Avoid

  • This combination can interact with other nonsteroidal anti-inflammatory medicines, corticosteroids (such as prednisone), and anticoagulants (like warfarin). Antihypertensives (atenolol) and diuretics (furosemide) might lose effectiveness when taken alongside this medication.

Overdose and Missed Dose

  • Taking more than the prescribed dose may cause symptoms such as nausea, vomiting, stomach pain, drowsiness, low blood pressure, or in severe cases, liver damage due to excess paracetamol. If you suspect an overdose, stop taking the medicine and seek emergency medical attention immediately.
  • If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For minor side effects like nausea or dizziness, try lying down for a while until the feeling passes.
  • If you experience dry mouth as a side effect, stay hydrated by drinking plenty of water.

Use in Driving and Operating Machinery

  • This medication might cause drowsiness. Therefore, it is advised not to drive or operate heavy machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

  • Pregnant or nursing women should avoid taking this medicine. A doctor's consultation is necessary as it falls under pregnancy category C.

Caution in Other Conditions

  • People with cardiovascular disease are advised to use this medicine with caution.
  • Elderly individuals should also take this medication under strict medical supervision.

Special Dietary and Lifestyle Recommendations

  • To manage pain and inflammation better, maintain a balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats.
  • Regular physical activity may help in managing inflammation better.
  • Adequate rest is essential for managing pain. Try to get enough sleep every night.
  • Stress management techniques like deep breathing, yoga, and meditation can also help in better management of pain and inflammation.

Frequently asked questions

No, this combination is not a steroid. It consists of Diclofenac, an anti-inflammatory medicine, Paracetamol / Acetaminophen, a pain reliever and fever reducer, and Tizanidine, a muscle relaxant.

Tizanidine, one of the components of this combination, can cause some side effects on the central nervous system, such as dizziness and somnolence, which might potentially affect your mood. If you experience any significant mood changes while taking this medicine, consult your doctor.

If you are allergic to any of the three components in this combination or other NSAIDs, you should not take this medication. Always let your doctor know about your allergies before starting any new medication.

The pain-relieving effect of this combination medicine begins within 20-30 minutes of taking the tablets. However, maximum effects are usually seen within a few days of regular dosing.

This combination should be used at the lowest effective dose for the shortest possible duration to minimise the risk of side effects. Long-term use can lead to serious gastrointestinal, cardiovascular, liver and blood-related side effects.

Diclofenac may affect fertility in some individuals, especially with long-term use. There is no strong evidence suggesting that Paracetamol or Tizanidine affects fertility. If you have concerns, consult your doctor for personalized advice.

This combination can cause drowsiness and insomnia as side effects. If these effects persist or become bothersome, consult your doctor.

Terms & Conditions


List of medicines for Diclofenac + Paracetamol/Acetaminophen + Tizanidine

Douse Mr 50/325/2 Mg Tablet Mr 10
Douse Mr 50/325/2 Mg Tablet Mr 10
Aspire Remedies
Pack of 10 Units
₹37.74
MRP ₹47.17
20% OFF
Infatiz P 50/325/2 Mg Tablet 10
Infatiz P 50/325/2 Mg Tablet 10
Agron Remedies Pvt. Ltd.
Pack of 10 Units
₹36.9
MRP ₹46.12
20% OFF
Bentiz Kp 50/325/2 Mg Tablet 10
Bentiz Kp 50/325/2 Mg Tablet 10
Ben Pharma
Pack of 10 Units
₹36.75
MRP ₹45.94
20% OFF
Posture 50/325/2 Mg Tablet 10
Posture 50/325/2 Mg Tablet 10
Elder Pharmaceuticals Ltd
Pack of 10 Units
₹26.71
MRP ₹33.39
20% OFF
Dilona Mr 50/325/2 Mg Tablet Mr 10
Dilona Mr 50/325/2 Mg Tablet Mr 10
Mapra Laboratories Pvt. Ltd
Pack of 10 Units
₹132.5
MRP ₹165.63
20% OFF
Dipane Mr 50/325/2 Mg Tablet Mr 10
Dipane Mr 50/325/2 Mg Tablet Mr 10
Wockhardt Ltd
Pack of 10 Units
₹8.44
MRP ₹10.55
20% OFF
Tizalud Dp 50/325/2 Mg Tablet 10
Tizalud Dp 50/325/2 Mg Tablet 10
Ravenbhel Pharmaceuticals Pvt Ltd.
Pack of 10 Units
₹51.3
MRP ₹64.12
20% OFF
Vozox Mr 50/325/2 Mg Tablet Mr 10
Vozox Mr 50/325/2 Mg Tablet Mr 10
Macmillon Pharmaceuticals
Pack of 10 Units
₹44.55
MRP ₹55.69
20% OFF

Subscribe

Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.

Registered Office Address

Intellihealth Solutions Private Limited
Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.
CIN: U62099MH2019PTC320566
Telephone:09240250346

Grievance Officer

Name: Kishor Kumar

Download Truemeds

Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.
Playstore
Apple App  Store

Contact Us

Our customer representative team is available 7 days a week from 9 am - 9 pm.


v4.28.10

copyright

2026 - Truemeds | All rights reserved. Our content is for informational purposes only. See additional information.

Trust Certified

Our Payment Partners

paymentPartnerpaymentPartnerpaymentPartnerpaymentPartner
paymentPartnerpaymentPartnerpaymentPartnerpaymentPartner