Paracetamol/Acetaminophen + Tramadol is primarily used for pain management, such as post-operative pain, dental pain, and pain associated with musculoskeletal disorders. This combination belongs to the group of analgesics.
It is also useful when non-opioid analgesics alone are insufficient for pain management.
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Paracetamol/Acetaminophen + Tramadol is a combination pain reliever belonging to the class of medicines called analgesics.
Paracetamol, also known as Acetaminophen, works by blocking the production of prostaglandins, compounds in the body that cause pain and fever. It also impacts the endogenous cannabinoid system and serotonergic pathways in the body, which are involved in pain management.
Tramadol, an opioid analgesic, acts on the central nervous system and inhibits the reuptake of serotonin and norepinephrine. This enhances descending pain inhibitory pathways, meaning it increases the body's ability to suppress pain signals.
Doctor of Medicine
BMS, FMC, MD Resident
Paracetamol/Acetaminophen + Tramadol is available for oral use in various dosage forms such as capsules and tablets.
For more severe cases, this medication is also available as an injectable solution. This form is typically administered intravenously in hospital settings.
This medicine is meant for adults and children above 12 years of age when prescribed by a doctor.
Paracetamol/Acetaminophen + Tramadol is contraindicated in patients with severe respiratory depression or bronchial asthma.
The combination of Paracetamol/Acetaminophen + Tramadol may interact with anticoagulants (like warfarin and aspirin) and Selective Serotonin Reuptake Inhibitors (SSRIs like citalopram and escitalopram).
An overdose of Paracetamol/Acetaminophen + Tramadol can lead to serious health complications, including liver damage and respiratory depression. If you suspect an overdose, seek immediate medical attention.
If you miss a dose of this medicine, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose. Do not double up on doses to make up for a missed one.
Most side effects of Paracetamol/Acetaminophen + Tramadol are temporary, generally harmless, and resolve after discontinuing this medicine. However, if you experience severe side effects or worsening symptoms, please consult your doctor.
To manage constipation, increase your intake of fluids and fibre-rich foods.
For a dry mouth, frequent sips of water can help maintain mouth hydration.
Paracetamol/Acetaminophen + Tramadol may cause dizziness or sleepiness. It is advised to avoid driving or operating heavy machinery until you know how this medication affects you.
The use of Paracetamol/Acetaminophen + Tramadol should be avoided during pregnancy and breastfeeding unless the benefits outweigh the risks. Consult your doctor before using this medicine.
Patients with liver impairment should exercise caution while using Paracetamol/Acetaminophen + Tramadol due to the risk of hepatotoxicity.
Similarly, patients with severe kidney impairment might need dose adjustments.
Ensure you stay hydrated, especially if you are experiencing side effects like dry mouth or constipation.
Limit your alcohol intake, as it can increase the risk of liver damage.
Regular rest and sleep can help manage side effects such as drowsiness and fatigue.
Frequently asked questions
Yes, there is a risk of addiction with long-term use of this medicine. Tramadol, which is an opioid analgesic, has the potential for abuse and addiction. Therefore, it's important to take this medicine exactly as prescribed by your doctor.
Your body can potentially develop a tolerance to this medicine, and you might need higher doses over time. This is why it is important to use this medicine only under the guidance of a doctor.
No, you should not stop taking Paracetamol/Acetaminophen + Tramadol abruptly, as it can lead to withdrawal symptoms. Always consult your doctor before you decide to stop this medicine.
No, if you are allergic to paracetamol, you should not take this medicine. Inform your doctor about all known allergies before starting this medicine.
The effectiveness of natural alternatives can vary considerably, and they may not be suitable for moderate-to-severe pain. Always consult with your doctor before trying any natural alternatives for pain relief.
Tramadol, one of the components of this medicine, can potentially affect your mood and behaviour. If you notice any such changes while on this medicine, inform your doctor.
The composition of the medicine varies depending on the manufacturer. If you are concerned about animal-derived ingredients, consult your doctor for more information.
Paracetamol/acetaminophen + Tramadol in other salts
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