Metoclopramide + Paracetamol/Acetaminophen is primarily used for the acute management of migraine attacks in adults. This combination belongs to the group of antiemetic and analgesic medicines.
Drowsiness
Dizziness
Headache
Dry mouth
Diarrhoea
Metoclopramide is a dopamine receptor antagonist. It works by blocking dopamine receptors in an area of the brain known as the chemoreceptor trigger zone (CTZ), which helps to reduce feelings of nausea and vomiting. It also increases the movement of the stomach and intestines, which aids digestion.
Paracetamol/Acetaminophen is a non-opioid analgesic and antipyretic. It works by blocking chemicals in the brain that send pain signals and regulate body temperature, helping to decrease pain and fever.
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Metoclopramide + Paracetamol/Acetaminophen is available as an oral tablet formulation.
Metoclopramide + Paracetamol/Acetaminophen is meant for use in adults and not recommended for use in children below 18 years.
Metoclopramide + Paracetamol/Acetaminophen is contraindicated in patients with known hypersensitivity to either of the components, in those with gastrointestinal haemorrhage or obstruction or perforation, in those with pheochromocytoma (a rare tumour of the adrenal gland) or epilepsy, with Parkinson's disease, and with severe liver or kidney impairment.
Metoclopramide + Paracetamol/Acetaminophen may interact with anticholinergic medications (e.g., dicyclomine and propantheline), medications that delay gastric emptying like opioids (e.g., tramadol), antocoagulants (e.g., warfarin), anticonvulsants (e.g., carbamazepine, hydantoins), antibiotics (e.g., isoniazid, or platelet inhibitory agents (e.g., sulfinpyrazone).
Excessive intake of Metoclopramide + Paracetamol/Acetaminophen may intensify adverse effects such as extrapyramidal reactions (involuntary, uncontrollable movements), drowsiness, disorientation, and seizures. In case of an overdose, immediate medical attention should be sought.
If you miss a dose of this medicine, take it as soon as you remember. However, avoid taking a double dose to make up for the missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of fluids can help manage headaches and dry mouth.
Rest and avoid strenuous activity if feeling dizzy or fatigued.
Metoclopramide + Paracetamol/Acetaminophen may cause drowsiness or dizziness. It is therefore advisable not to drive or operate heavy machinery until you know how the medicine affects you.
The use of Metoclopramide + Paracetamol/Acetaminophen during pregnancy or while breastfeeding should be discussed with your doctor, due to the potential risks involved.
Patients with liver or kidney issues should exercise caution when taking Metoclopramide + Paracetamol/Acetaminophen. These conditions can affect how well your body processes the medicine, and may require dosage adjustments or special tests during treatment.
Avoiding known personal triggers for migraines, such as certain foods or fragrances, can be beneficial.
Frequently asked questions
No, weight gain is not a typical side effect of Metoclopramide + Paracetamol/Acetaminophen. However, individual reactions to medication can vary, and if you notice any unexpected changes in your weight, you should consult your doctor.
The safety of daily use of Metoclopramide + Paracetamol/Acetaminophen depends on individual health conditions and the duration of the treatment. Always take this medicine as prescribed by your doctor.
No, Metoclopramide + Paracetamol/Acetaminophen is not a steroid. It is a combination medication used for the management of acute migraine attacks.
There is no conclusive evidence to suggest that Metoclopramide + Paracetamol/Acetaminophen affects fertility in men or women. However, if you are planning to conceive, please consult your doctor before taking this medicine.
Yes, one of the common side-effects of Metoclopramide + Paracetamol/Acetaminophen can be drowsiness or fatigue which might affect your sleep patterns.
Each individual may respond differently to the medication. Generally, this combination starts working within 30 minutes to 2 hours after oral administration.
No, Metoclopramide + Paracetamol/Acetaminophen is not typically available over the counter and requires a prescription from a doctor.
Metoclopramide + Paracetamol/acetaminophen in other salts
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