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CompositionSacurise 100 Tablet is used in the treatment of chronic heart failure in adults with reduced ejection fraction to significantly reduce the risk of cardiovascular death and the need for hospitalisation. This medication, an angiotensin receptor neprilysin inhibitor (ARNI), works as a comprehensive management solution by reducing the strain on the heart, promoting the excretion of excess fluid, and improving the heart's overall pumping function.
Sacurise 100 Tablet is used for the management of chronic heart failure in adults, working to improve heart function and significantly reduce the risk of cardiovascular events in heart failure patients by modulating the body's natural vasoactive peptide systems.
Here's how you should take Sacurise 100 Tablet:
Sacurise 100 Tablet is taken orally.
Sacurise 100 Tablet may cause low blood pressure, hyperkalemia (high potassium levels), diarrhoea, dizziness, and cough. Speak with your healthcare provider if these side effects continue.
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Sacurise 100 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Dizziness: If you feel dizzy after taking this medicine, try lying down until it passes.
Diarrhoea: Try taking Sacurise 100 Tablet with food to lessen this effect.
Sacurise 100 Tablet consists of two active ingredients:
Sacubitril (49 mg): This component is a neprilysin inhibitor. It works by blocking the action of an enzyme called neprilysin in your body. Neprilysin is responsible for breaking down natriuretic peptides that help relax blood vessels and remove excess sodium and fluid from the body.
Valsartan (51 mg): As an angiotensin II receptor blocker (ARB), valsartan blocks the action of angiotensin II, a hormone that can cause blood vessels to narrow and increase blood pressure.
Together, these components work to reduce strain on the heart and improve its pumping ability.
Sacurise 100 Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.
Sacurise 100 Tablet is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.
Caution is advised while taking Sacurise 100 Tablet if you consume alcohol regularly. It is best to consult your doctor before taking this medicine.
It is advisable to discuss liver-related concerns with your doctor before starting treatment with Sacurise 100 Tablet. They will evaluate if this medicine is suitable.
Caution is advised before using Sacurise 100 Tablet if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.
If you experience dizziness or lightheadedness after taking Sacurise 100 Tablet, avoid driving or operating heavy machinery until these symptoms pass.
Do not take Sacurise 100 Tablet if you are allergic to sacubitril, valsartan, or any of the other ingredients in the tablet formulation. Notify your doctor about any known allergies before starting this medication.
Sacurise 100 Tablet is meant for adult use only. Consult your doctor before giving this medicine to children under 18 years of age.
Older patients should take Sacurise 100 Tablet under medical supervision, as they may be more susceptible to its side effects. Caution is advised if patients are over 70 years of age. Your doctor will guide you based on your health status.
Sacurise 100 Tablet interacts with the following medicines:
Potassium Supplements: Taking potassium supplements alongside Sacurise 100 Tablet can lead to an increase in your blood's potassium levels, known as hyperkalemia. This includes specific medicines such as Potrate and Kay Ciel.
Potassium-Sparing Diuretics: Medicines like amiloride or spironolactone, which help your body get rid of excess water while keeping potassium, can also cause hyperkalemia when taken with this tablet.
Certain dietary elements can interact with Sacurise 100 Tablet, including:
Salt Substitutes: Some table salt substitutes like pink salt, rock salt contain high amounts of potassium which can heighten the risk of hyperkalemia when used in conjunction with Sacurise 100 Tablet.
Sacurise 100 Tablet interacts with the following diseases:
Liver Disease: If you have liver problems, it's important to closely monitor your condition while using Sacurise 100 Tablet as it could potentially worsen your condition.
Kidney Disease: Reduced kidney function can affect how well Sacurise 100 Tablet works. If you have kidney disease, careful monitoring is recommended during the use of this medication.
You should take the daily dose of Sacurise 100 Tablet as directed by your doctor. The dosage might vary based on individual factors such as your health condition and how you respond to the medicine. It's important not to change the prescribed dosage without consulting your doctor.
If you accidentally take more than the prescribed dose of Sacurise 100 Tablet, you might experience overdose symptoms such as a significant drop in blood pressure or high potassium levels in your blood. If this happens, it's crucial to let your doctor know.
If you forget to take Sacurise 100 Tablet at the scheduled time, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed one and continue with your regular dosage schedule. Never increase your dosage without consulting your doctor.
Store Sacurise 100 Tablet at room temperature, specifically below 30°C.
Keep it secured in its original packaging to protect it from moisture.
Avoid exposing the medicine to direct sunlight or heat.
Store it in a place unreachable by children.
Make sure you take this medicine before its expiration date.
High salt content can burden your heart, making the condition worse. Therefore, keep your salt intake minimal while taking Sacurise 100 Tablet.
Regular exercise tailored to your ability can strengthen your heart muscles and improve overall heart health. Always consult your doctor about the right level of activity for you.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Chronic Heart Failure |
| Drug Category | Neprilysin Inhibitor, Angiotensin II Receptor Blocker |
| Therapeutic Category | Heart Failure Management |
Sacurise 100 Tablet is primarily used to manage chronic heart failure in adults.
The medicine works by reducing strain on the heart and helping improve its pumping ability.
This medicine should be taken orally, with or without food, at the same time each day.
Common side effects include low blood pressure and increased potassium levels in the blood.
If you have a history of kidney disease, consult your doctor before starting this medication.
If you miss a dose, take it as soon as you remember, unless it's nearly time for your next dose.
Sacurise 100 Tablet is not recommended for use during pregnancy or breastfeeding. Consult your doctor for advice.
Check out Editorial Policy
Food and Drug Administration. (2016). Draft guidance on Sacubitril; Valsartan. https://www.accessdata.fda.gov/drugsatfda_docs/psg/Sacubitril;%20Valsartan_oral%20tablet_RLD%20207620_RC04-16.pdf
CENTER FOR DRUG EVALUATION AND RESEARCH. (2015). Approval Package for: ENTRESTO Tablets, 24 mg/26 mg, 49 mg/51 mg, and 97 mg/103 mg. In CENTER FOR DRUG EVALUATION AND RESEARCH. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2015/207620Orig1s000Approv.pdf
DailyMed - ENTRESTO- sacubitril and valsartan tablet, film coated ENTRESTO- sacubitril and valsartan pellet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=000dc81d-ab91-450c-8eae-8eb74e72296f
Sacubitril: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09292
Valsartan: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00177
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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