Zeblong 8 Tablet contains azelnidipine as its active ingredient. Azelnidipine works by inhibiting the movement of calcium ions into both the smooth muscles surrounding blood vessels and the muscles of the heart. This mechanism leads to relaxation of the blood vessels and improved blood flow to the heart muscles, resulting in lower blood pressure.
The precise process involves azelnidipine binding to specific calcium channels in these muscle cells, preventing calcium from entering them. As a result, smooth muscle relaxation occurs in the walls of blood vessels, dilating them and reducing resistance against blood flow. Additionally, this action helps decrease the workload on the heart by reducing cardiac muscle contraction force.
By targeting these specific calcium channels, the Zeblong 8 Tablet effectively lowers blood pressure and improves cardiovascular function with a favourable tolerability profile.