Zerodol Mr Tablet 10

Ipca Laboratories Pvt Ltd.

Strip of 10 Units

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Old MRP ₹130.9

MRP ~~₹122.72~~

₹98.18

₹12.27/Units

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Composition

Aceclofenac (100 Mg) + Tizanidine (2 Mg)

Zerodol-MR Tablet is used to relieve pain, inflammation, and stiffness caused by conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, and headaches. It combines two medicines: Tizanidine, which helps relax muscles and reduce stiffness, and Aceclofenac, which reduces pain and swelling. Together, they work to ease muscle spasms and relieve mild to moderate pain and inflammation, helping you feel more comfortable and move better. It is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, and headache. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

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Zerodol-MR Tablet is used to relieve pain and inflammation in arthritis, muscle pain, bone and joint pain, tooth pain, headache, and muscle spasms.

Follow these instructions while taking Zerodol-MR Tablet:

Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
Always take the tablets with food to minimise the risk of stomach upset.
Do not take more than the recommended dose without consulting your doctor.
Remember not to stop taking this medicine without first consulting your doctor.

Zerodol-MR Tablet is taken orally.

Zerodol-MR Tablet may cause some side effects, including nausea, vomiting, stomach pain or heartburn, diarrhoea, loss of appetite, dry mouth, and drowsiness. These side effects are usually mild and temporary, and they often go away once you stop taking the medicine.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Zerodol-MR Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Stomach pain or heartburn: Take Zerodol-MR Tablet with food to lessen this effect.
Drowsiness: Consider taking this medicine at night if it makes you tired during the day.

Zerodol-MR Tablet works through the combined effects of two active components:

Aceclofenac (100 mg): This NSAID reduces pain, inflammation and swelling by inhibiting cyclooxygenase (COX) enzymes. These enzymes are responsible for producing prostaglandins - chemicals that trigger pain and inflammation.
Tizanidine (2 mg): This muscle relaxant acts on alpha-2 adrenergic receptors in the brain and spinal cord, reducing nerve impulses sent to the muscles. This action promotes muscle relaxation, effectively reducing muscle spasms and enhancing muscle movement.

Pregnancy

Zerodol-MR Tablet is contraindicated during pregnancy, especially in the last trimester. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Caution is advised if you are nursing. It is best to consult your doctor before taking this medicine.

Alcohol

Consuming alcohol while taking Zerodol-MR Tablet is not recommended as it can increase drowsiness and may cause liver damage.

Liver

Caution is advised while taking Zerodol-MR Tablet in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Zerodol-MR Tablet.

Kidney

If you have a history of kidney problems, consult your doctor before taking Zerodol-MR Tablet.

Using Machines & Driving

Zerodol-MR Tablet can cause drowsiness and impact your ability to drive or operate machinery. Ensure you know how this medicine affects you before driving or operating machinery.

Allergy

If you are allergic to aceclofenac, tizanidine, or any other ingredients in the product, avoid taking Zerodol-MR Tablet. Always inform your doctor about any allergies before starting this medication.

Children

Caution is advised while giving Zerodol-MR Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Caution is advised if patients are over 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Zerodol-MR Tablet interacts with the following medicines:

Non-steroidal anti-inflammatory Drugs (NSAIDs) like ibuprofen and aspirin, when combined with Zerodol-MR Tablet, might increase the risk of stomach bleeding or ulceration.
Blood thinning medicines such as warfarin may interact with Zerodol-MR Tablet, potentially increasing the risk of bleeding.
Antidepressants like fluoxetine and escitalopram can interact with Zerodol-MR Tablet, possibly increasing the risk of side effects like drowsiness and dizziness.
Blood pressure medications like amlodipine or lisinopril alongside Zerodol-MR Tablet may affect blood pressure control.

Drug-Food Interactions

Foods that can interact with Zerodol-MR Tablet:

High potassium foods: Foods rich in potassium, like bananas and spinach, could potentially enhance the risk of high potassium levels when consumed while taking Zerodol-MR Tablet.

Drug-Disease Interactions

Zerodol-MR Tablet interacts with the following diseases:

Kidney disease: Patients having kidney problems should use Zerodol-MR Tablet cautiously as it could potentially worsen their condition.
Liver disease: The medicine might exacerbate symptoms in individuals suffering from liver disease; hence, caution is advised.
Asthma: Asthmatic patients should be cautious while using this medication as it might cause breathing difficulties.
Bleeding disorders: Patients with bleeding disorders should use this medication cautiously as it may increase the risk of bleeding.

Daily Dose

Your doctor will guide you on how to take Zerodol-MR Tablet based on factors like the severity of your condition and your response to the medication. It is crucial to follow these instructions and avoid adjusting your dosage without consulting your doctor.

Over Dose

Overdosing on Zerodol-MR Tablet may lead to side effects such as nausea, vomiting, stomach pain, and drowsiness. Should you experience these symptoms after taking more than the recommended dose, inform your doctor.

Missed Dose

If you forget to take your Zerodol-MR Tablet, do it as soon as you remember. However, if it's close to the time for your next dose, skip the missed one and continue with your regular schedule. Always consult with your doctor before making any changes to the dosage.

Keep Zerodol-MR Tablet in a dry place, ideally at room temperature.
Protect the medicine from excessive light and moisture.
Make sure to store it out of reach of children for safety reasons.
Always check the expiry date before using the medicine.

If you experience muscle spasms, it might help to maintain hydration by drinking plenty of fluids. This can assist in preventing cramps.
Incorporating gentle exercise or stretching routines into your daily schedule could also be beneficial. These may help improve muscle flexibility and reduce stiffness. It is advisable to consult your doctor for specific exercises.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Muscle spasms, pain, inflammation
Drug Category	NSAID, muscle relaxant
Therapeutic Category	Pain relief

What is the Zerodol-MR Tablet used for?

Zerodol-MR Tablet is used to treat muscle pain, stiffness, swelling, and joint discomfort caused by conditions like sprains, strains, arthritis, and injuries. It helps relax muscles, reduce inflammation, and relieve pain for easier movement. Doctors often prescribe it for back pain, neck pain, or musculoskeletal disorders to improve daily comfort and mobility.

How does the Zerodol-MR Tablet work?

The aceclofenac in Zerodol-MR reduces pain, inflammation, and swelling, while tizanidine helps muscles relax and reduces spasms.

How should I take the Zerodol-MR Tablet?

You should take the Zerodol-MR Tablet orally as directed by your doctor. Always take it with food.

Can I consume alcohol while taking Zerodol-MR Tablet?

Avoid consuming alcohol while taking this medicine, as it can increase drowsiness and potentially harm your liver.

Is it safe to take Zerodol-MR Tablet during pregnancy?

It is best to consult your doctor before taking Zerodol-MR during pregnancy, especially in the last trimester.

What should I do if I miss a dose of Zerodol-MR Tablet?

If you miss a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one.

Can Zerodol-MR Tablet cause any side effects?

Yes, potential side effects include nausea, stomach pain, diarrhoea, loss of appetite, dry mouth and drowsiness. Consult your doctor if these persist.

Is Zerodol MR Tablet good for neck pain?

Yes, Zerodol-MR is used to treat conditions such as muscle spasms and stiffness, back and neck pain, as well as sprains and strains.

Last Updated On 13 Nov. 2025 | 7:47AM (IST)

Certified Content

Written by

Dr. Meenakshi Maruwada

Medical Content Writer | 9 years

BDS, PGCAD, GMHE (IIM-B)

Reviewed by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Check out Editorial Policy

Manufacturer details

125, Charkop Rd, Kandivali, Charkop, Charkop Industrial Estate, Kandivali West, Mumbai, Maharashtra 400067

Country of origin: INDIA

Expiry on or after: March 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

National Library of Medicine. (n.d.). Tizanidine: MedlinePlus drug information. MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a601121.html
Acorda Therapeutics Inc. (2013, November). ZANAFLEX Capsules® (tizanidine hydrochloride) capsules, for oral use. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021447s011_020397s026lbl.pdf
PubChem. (n.d.). Aceclofenac. https://pubchem.ncbi.nlm.nih.gov/compound/Aceclofenac
Aceclofenac. (n.d.). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB06736
Moore, R. A., Derry, S., & McQuay, H. J. (2009). Single dose oral aceclofenac for postoperative pain in adults. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.cd007588

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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