Duopil 1/500 Tablet 10

Duopil 1/500 Tablet is used in adults to manage type 2 diabetes by controlling blood sugar levels when diet, exercise and a single medicine are not enough.

Uses of Duopil 1/500 Tablet are:

• Type 2 Diabetes: Helps control blood sugar levels in adults with type 2 diabetes.

• Combination Therapy: Offers better blood sugar control than either ingredient used alone.

• Long-term Blood Sugar Management: Supports better long-term blood sugar control alongside diet and exercise.

Using Duopil 1/500 Tablet involves the following steps:

• Always swallow the tablet whole with a glass of water.

• Do not chew or crush the tablet.

• Always take your medicine during a meal to minimise gastrointestinal side effects.

• Ensure that you do not exceed the recommended dose without consulting your doctor.

• Remember not to stop taking this medicine without discussing it with your doctor.

Duopil 1/500 Tablet is taken orally.

Duopil 1/500 Tablet contains two key active ingredients:

• Metformin (500 mg): Metformin is a biguanide which works in three ways: it decreases glucose production by the liver, reduces intestinal absorption of glucose, and enhances insulin sensitivity by increasing peripheral glucose uptake and utilisation. The activation of a liver enzyme known as AMPK plays a vital role in insulin signalling, energy balance, and glucose and fat metabolism.

• Glimepiride (1 mg): This component belongs to the sulfonylurea class of medications. It primarily works by stimulating pancreatic beta cells to release more insulin into the body. By binding to specific receptors on the beta cell surface, it blocks ATP-sensitive potassium channels, which trigger the secretion of preformed insulin granules.

Together, these components work synergistically in Duopil 1/500 Tablet to manage high blood sugar levels effectively.

• Store Duopil 1/500 Tablet in a cool, dry place where the temperature stays below 30°C.

• Protect the medicine from light and moisture to maintain its effectiveness.

• Always keep this medication out of the reach of children.

• Ensure you use this medicine before the expiry date printed on the pack.

• Maintain a balanced diet low in sugars and high in fibre to support your body's insulin sensitivity. This will enhance the effectiveness of Duopil 1/500 Tablet in managing your type 2 diabetes.

• Regular physical exercise is beneficial. Activities like walking, swimming or cycling can help control blood sugar levels and improve your body's response to insulin.