Grandem Syrup is used to prevent and treat nausea and vomiting linked to chemotherapy, radiation therapy, and surgery. It contains granisetron, an anti-sickness medicine that works by blocking the serotonin (5-HT3) signals in the brain and gut that trigger the vomiting reflex, helping to prevent and control nausea and vomiting during treatment and recovery.
Give the syrup exactly at the prescribed dose and timing, especially around cancer treatment or after surgery. Consult your doctor before use, and tell them if you have any heart-rhythm problems or salt imbalances. If the nausea continues despite treatment, or if you experience unusual side effects such as severe headaches or constipation, check with your doctor promptly.
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Grandem Syrup 10ml
Bottle of 10 ML
MRP ₹60.5
₹51.43
₹6.05/ML
15% off
*MRP inclusive of all taxes100% genuine medicines
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15 days Easy returns
Prescription required for this medicine
Store Below 30° C
CompositionAbout Grandem Syrup
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Uses of Grandem Syrup
Grandem Syrup is used to prevent and treat nausea and vomiting associated with chemotherapy, radiotherapy, and surgical procedures. By reducing vomiting episodes, the medication improves patient comfort and supports a smoother recovery process during intensive medical treatments.
Directions for Use of Grandem Syrup
To use Grandem Syrup:
- Take Grandem Syrup exactly as prescribed, without changing the dose or frequency.
- Seek advice from your doctor for specific guidance on using this syrup.
Remember, always consult your doctor for personalized guidance on using Grandem Syrup.
Route of Administration
Grandem Syrup is taken orally, which means it is consumed by swallowing it. It is not to be taken in any other way.
Side Effects of Grandem Syrup
Grandem Syrup may cause headache, constipation, insomnia, diarrhea, stomach discomfort, fatigue, mild dizziness, and temporary changes in bowel habits.
Management Of Side Effects:
To manage these side effects, you can try the following natural remedies:
- Headache: Rest in a quiet, dark room and apply a cool compress to your forehead.
- Constipation: Eat fibre-rich foods like fruits, vegetables, and whole grains. Stay hydrated and exercise regularly to promote regular bowel movements.
- Insomnia: Establish a relaxing bedtime routine, avoid caffeine and electronics before bed, and create a comfortable sleep environment.
- Diarrhoea: Drink plenty of fluids to stay hydrated and consume bland foods like bananas, rice, and toast until your symptoms improve.
How Grandem Syrup Works?
Grandem Syrup contains the active ingredient granisetron hydrochloride.
- It works by inhibiting a receptor called 5-HT3 receptors that are present in both the brain and gastrointestinal tract.
- By blocking these receptors, it prevents the stimulation of the vomiting centre, thus preventing nausea and vomiting.
- The exact chemical process involved in the inhibition of serotonin (a natural substance in the body) from binding to these receptors and triggering a nausea and vomiting response.
Safety Measures & Warnings
Pregnancy
If you are pregnant or planning to become pregnant, it is advisable to consult your doctor before using Grandem Syrup. They will determine if the benefits outweigh any potential risks.
Breastfeeding
For breastfeeding women, it is recommended to consult your doctor before using Grandem Syrup as it is uncertain if the medication passes into breast milk.
Alcohol
It is advisable to limit alcohol consumption while taking Grandem Syrup as it may increase the risk of certain side effects.
Liver
Individuals with liver problems should exercise caution when using Grandem Syrup and consult their doctor for proper guidance.
Kidney
If you have kidney issues, it is important to inform your doctor before starting Grandem Syrup as dosage adjustments may be necessary.
Use In Driving And Operating Machinery
Grandem Syrup may cause drowsiness or dizziness in some individuals. If you experience these effects, avoid operating machinery or driving until you feel alert again.
Allergy
Inform your doctor about any allergies you have, especially if you are allergic to granisetron or any other medications.
Children
Grandem Syrup should not be given to children below 2 years of age.
Older Patients
Elderly individuals (65 years and older) should consult their doctor before taking Grandem Syrup.
Interactions of Grandem Syrup
Drug-Drug Interactions
Certain medications can interact with Grandem Syrup, including:
- Anti-depressants: Fluoxetine, Sertraline
- Anti-fungal medications: Ketoconazole, Fluconazole
- Pain medications: Tramadol, Fentanyl
- Migraine medications: Sumatriptan, Rizatriptan
- Anti-anxiety medications: Diazepam, Alprazolam
Drug-Food Interactions
There are no specific food interactions known with Grandem Syrup.
Drug-Disease Interactions
- Individuals with heart disease should exercise caution when using Grandem Syrup.
- Patients with intestinal blockages should avoid this medication.
- Electrolyte abnormalities may interact with Grandem Syrup.
- Those diagnosed with serotonin syndrome should not use this syrup.
- Cancer patients undergoing treatments that may damage the heart should consult their doctor before using Grandem Syrup.
If you have any pre-existing conditions related to these diseases, it is important to inform your doctor before using this syrup.
Dosage of Grandem Syrup
Daily Dose
Take Grandem Syrup as directed by your doctor. The dosage will depend on factors such as the severity of your condition and your body's response to treatment. Follow your doctor's prescribed dosage and do not exceed it without consulting them.
Over Dose
If you accidentally take too much Grandem Syrup, seek immediate medical attention. Contact your doctor or go to a nearby hospital. Using this medicine more frequently than prescribed can lead to common side effects.
Missed Dose
If you forget to take Grandem Syrup as instructed, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and continue with your regular dosage schedule. Never increase your dosage without consulting your doctor.
Storage
- Store Grandem Syrup at room temperature below 30°C.
- Keep the medicine in its original container, tightly closed.
- Protect it from excessive heat and moisture.
- Keep Grandem Syrup out of reach of children.
- Use the product before its expiry date.
Special Dietary And Lifestyle Recommendation
- Stay hydrated by drinking plenty of fluids throughout the day.
- Eat small, frequent meals to avoid an empty stomach.
- Avoid spicy, greasy, or heavy foods that can trigger nausea or vomiting.
- Practice relaxation techniques like deep breathing or meditation to help manage stress and anxiety.
- Get plenty of rest and sleep to support overall well-being.
- If you experience constipation, consume fibre-rich foods and stay physically active through regular exercise.
- Consult your doctor for additional dietary and lifestyle recommendations based on your specific needs.
Quick Tips
- Take Grandem Syrup as directed by your doctor.
- Inform your doctor about any pre-existing conditions.
- Stay hydrated if you experience diarrhoea.
- Consume fibre-rich foods to manage constipation.
Fact Box
| Dosage Forms Available | Syrup |
| Habit Forming | Non-addictive |
| Ailment | Nausea and vomiting caused by medical treatments |
| Drug Category | Anti-emetic |
| Therapeutic Category | Nausea and vomiting management |
Frequently Asked Questions (FAQs)
What is Grandem Syrup and what is it used for?
Grandem Syrup is a medication that contains the active ingredient granisetron, which is an anti-emetic used to prevent or manage nausea and vomiting caused by medical treatments like chemotherapy, radiation therapy, and post-surgery.
How does Grandem Syrup work?
Grandem Syrup works by blocking a receptor called 5-HT3 receptors in the brain and gastrointestinal tract. This prevents the stimulation of the vomiting centre, helping to prevent nausea and vomiting.
How should I take Grandem Syrup?
Grandem Syrup should be taken orally as directed by your doctor. It comes in the form of a syrup that should be swallowed whole with plenty of water. Do not crush or chew it.
Who can take Grandem Syrup?
Grandem Syrup is specifically used for adults and children above 2 years of age to prevent and manage nausea and vomiting caused by medical treatments like chemotherapy, radiation therapy, and post-surgery. However, pregnant or breastfeeding women should consult their doctor before using this syrup.
Are there any side effects of Grandem Syrup?
Common side effects of Grandem Syrup include headache, constipation, insomnia, and diarrhoea. If these side effects worsen or do not improve, it is important to consult with your doctor.
Can I take other medications while using Grandem Syrup?
It is important to inform your doctor about all the medications you are taking before starting Grandem Syrup as it may interact with certain medications.
How should I store Grandem Syrup?
Grandem Syrup should be stored at room temperature below 30°C in its original container, out of reach of children.
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Manufacturer details
23 A, Shah Industrial Estate, Off Veera Desai Rd, Andheri West, Mumbai, Maharashtra 400053
Country of origin: INDIA
Country of origin: INDIA
Expiry on or after: November 2026
In case of any issues, contact us:
support@truemeds.in|09240250346
Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071
References
- Aapro, M. (n.d.). Granisetron: an update on its clinical use in the management of nausea and vomiting. PubMed.gov. Retrieved from https://pubmed.ncbi.nlm.nih.gov/15561811/
- Anh L. Ngo, Vwaire Orhurhu, Ivan Urits, Edwin O. Delfin, Medha Sharma, Mark R. Jones, Omar Viswanath, Richard D. Urman. (2019). Extended-release granisetron: Review of pharmacologic considerations and clinical role in the perioperative setting. NIH National Library of Medicine, National Center for Biotechnology Information. Pubmed Central. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625288/
- KD. Tripathi. (2013). Antiemetic, Prokinetic and Digestant Drugs. Essentials of medical pharmacology. Seventh edition. Page –669.
- Matti Aapro. (n.d.). Granisetron: an update on its clinical use in the management of nausea and vomiting. NIH National Library of Medicine, National Center for Biotechnology Information. Pubmed.gov. Retrieved from https://pubmed.ncbi.nlm.nih.gov/15561811/
- Granisetron Hydrochloride Tablets. (n.d.). U.S. Food And Drug Administration. Retrieved August 8, 2023, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/078080Orig1s005lbl.pdf
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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