Oxramet Xr 10mg/500mg Tablet 7

Sun Pharma Laboratories Ltd.

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Composition

Dapagliflozin (10 Mg) + Metformin (500 Mg)

Oxramet XR 10mg/500mg Tablet is used to treat type 2 diabetes in adults. It combines an SGLT2 inhibitor and a biguanide to help control blood sugar levels.

In addition to this primary use, this medicine also helps in the control of blood sugar levels more effectively than metformin alone. It decreases the risk of cardiovascular events such as heart attacks and heart failure, thereby providing an added health benefit.

The medicine should be taken orally as directed by your doctor. Before starting this medicine, informing your doctor about any existing health conditions or ongoing medications would be beneficial. Immediately inform your doctor if you observe any side effects while taking this medication. To achieve the best results, continue taking this medicine for the duration prescribed by your doctor.

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Oxramet XR 10mg/500 mg Tablet is used for managing type 2 diabetes mellitus in adults, especially when diet and exercise alone do not provide sufficient blood sugar control. It also helps reduce the cardiovascular risk, lowering the likelihood of serious events such as heart attacks or heart failure.

Directions for Use of Oxramet Xr 10mg/500mg Tablet 7

Here's how you should take Oxramet XR 10mg/500mg Tablet :

Swallow the tablet whole with a glass of water. Avoid crushing or chewing it.
Take this medicine once daily with food, preferably at the same time each day.
Do not exceed the recommended dose without consulting your doctor.
Do not stop taking this medication without consulting your doctor first.

Oxramet XR 10mg/500mg Tablet is taken orally.

Side Effects of Oxramet Xr 10mg/500mg Tablet 7

Oxramet XR 10mg/500mg Tablet may have the following common side effects:

Sore throat, nasal congestion, runny nose
Headache
Nausea, vomiting, diarrhoea
Genital fungal infection (A yeast infection that can occur in the genital area.
Nasopharyngitis (An infection of the nose and throat)
Urinary tract infection
Polyuria (A condition where you urinate more than usual)
Flatulence (Excessive gas in the stomach or intestines)
Skin rash
Taste changes

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Oxramet XR 10mg/500mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here's how you can manage some common side effects:

Nausea, vomiting, diarrhoea: Try taking Oxramet XR 10mg/500mg Tablet with or after meals to reduce these symptoms.
Polyuria: Consider taking this medicine in the evening to avoid frequent urination during your daily activities.

How Oxramet Xr 10mg/500mg Tablet 7 Works?

Oxramet XR 10mg/500mg Tablet is a combination of two active ingredients which work together to manage type 2 diabetes mellitus:

Dapagliflozin (10 mg): As a sodium-glucose co-transporter 2 (SGLT2) inhibitor, dapagliflozin blocks glucose reabsorption in your kidneys. This leads to excess glucose being excreted through urine, thereby lowering blood sugar levels.
Metformin (500 mg): This biguanide reduces the amount of glucose your liver produces and increases insulin sensitivity. It improves how effectively your body's cells uptake and utilise glucose, which helps control blood sugar levels.

The synergistic effect of dapagliflozin and metformin in Oxramet XR 10mg/500mg Tablet helps manage type 2 diabetes mellitus more effectively.

Pregnancy

Oxramet XR 10mg/500mg Tablet is not recommended if you are pregnant. It is important to have a discussion with your doctor before starting this medicine if you are pregnant or planning to conceive.

Breastfeeding

If you are breastfeeding, it's best to consult your doctor before taking Oxramet XR 10mg/500mg Tablet. It is always important to weigh the benefits against potential risks under your doctor's guidance.

Alcohol

It would be wise to limit alcohol consumption while using Oxramet XR 10mg/500mg Tablet. Excessive alcohol intake could increase the risk of lactic acidosis, a serious side effect.

Liver

If you suffer from liver problems, caution is advised while taking Oxramet XR 10mg/500mg Tablet. It is always better to discuss your liver health with your doctor before beginning this medication.

Kidney

Oxramet XR 10mg/500mg Tablet is not recommended for patients with severe kidney impairment or end-stage renal disease. If you have a history of kidney problems, consult your doctor before starting this medicine.

Using Machines & Driving

There is no data suggesting that Oxramet XR 10mg/500mg Tablet affects your ability to drive or operate machinery. However, if you experience dizziness or other side effects that could affect your focus, avoid such activities and consult your doctor.

Allergy

If you are allergic to dapagliflozin, metformin or any other components of Oxramet XR 10mg/500mg Tablet, it would be wise not to take this medicine. Always inform your doctor about any known allergies.

Children

This medicine is intended for adults only. It should not be given to children under 18 years of age.

Older Patients

Older patients may be more susceptible to the side effects of Oxramet XR 10mg/500mg Tablet due to age-related organ function decline. It is advisable for older patients to take this medicine under medical supervision. Always discuss your health status with your doctor before starting on this medication.

Interactions of Oxramet Xr 10mg/500mg Tablet 7

Drug-Drug Interactions

Oxramet XR 10mg/500mg Tablet interacts with the following medicines:

Diuretics: Oxramet XR 10mg/500mg Tablet, when taken alongside diuretics like furosemide and hydrochlorothiazide, may increase the risk of dehydration and low blood pressure.
Other antidiabetic medications: Combining Oxramet XR 10mg/500mg Tablet with medications like insulin or glipizide could potentially increase the risk of low blood sugar (hypoglycemia).
Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs like ibuprofen and naproxen can interfere with kidney function, affecting the excretion of dapagliflozin and metformin.
Cationic drugs: Medicines such as amiloride, digoxin, or quinine may interact with metformin, affecting its absorption and elimination.

Drug-Food Interactions

Certain foods can affect how Oxramet XR 10mg/500mg Tablet works. Items to be aware of include:

Foods rich in carbohydrates: These can increase your blood sugar levels and may require adjustments in your medication dosage.

Drug-Disease Interactions

Oxramet XR 10mg/500mg Tablet interacts with the following diseases:

Renal Impairment: In patients with severe kidney problems, both dapagliflozin and metformin are less effectively eliminated from the body, which could potentially lead to harmful accumulation.
Metabolic Acidosis: Patients with metabolic issues such as lactic acidosis or diabetic ketoacidosis should not use Oxramet XR 10mg/500mg Tablet as it could worsen their condition.
Liver disease: Patients suffering from severe liver disease should exercise caution while taking this medicine as it may affect the metabolism and excretion of metformin.

Dosage of Oxramet Xr 10mg/500mg Tablet 7

Daily Dose

The daily dose of Oxramet XR 10mg/500mg Tablet should be taken exactly as prescribed by your doctor. The dosage can vary depending on factors like your specific health condition and how you respond to the medicine. For detailed instructions, please refer to the package insert.

Over Dose

If you accidentally take more Oxramet XR 10mg/500mg Tablet than prescribed, you may experience symptoms such as excessive urination or hypoglycaemia. Make sure to inform your doctor if these symptoms occur.

Missed Dose

If you forget to take a dose of Oxramet XR 10mg/500mg Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses without consulting your doctor.

Always keep your Oxramet XR 10mg/500mg Tablet tablets in a cool, dry place below 30°C.
Avoid exposure to direct sunlight and excessive heat.
Keep the medicine out of reach of children.
Ensure the packaging is not damaged or tampered with.
Use the tablets before their expiry date for best results.

Maintain a balanced diet rich in fibre and low in sugars to support blood sugar control, which is essential when managing type 2 diabetes.
Regular physical activity, such as a brisk walk or cycling, can help increase insulin sensitivity and manage your blood sugar levels effectively. Remember, consistency is key!

Fact Box

Drug Category	SGLT2 Inhibitor, Biguanide
Therapeutic Category	Antidiabetic
Available Dosage Types	Extended Release Tablet
Habit Forming	No
Ailment	Type 2 diabetes mellitus

What is Oxramet XR 10mg/500mg Tablet used for?

Oxramet XR 10mg/500mg Tablet is used to manage type 2 diabetes mellitus in adults when diet and exercise alone are not sufficient.

How does Oxramet XR 10mg/500mg Tablet work?

It contains two active ingredients, dapagliflozin and metformin, which effectively control blood sugar levels.

How should I take Oxramet XR 10mg/500mg Tablet?

Oxramet XR 10mg/500mg Tablet should be taken orally once daily with food at the same time each day. The tablet should not be crushed, chewed or broken.

What are the common side effects of Oxramet XR 10mg/500mg Tablet?

Common side effects include sore throat, headache, nausea, vomiting, diarrhoea, and urinary tract infections. If these persist or worsen, consult your doctor.

Can I drink alcohol while taking Oxramet XR 10mg/500mg Tablet?

Excessive alcohol intake is not advised while you are on this medication, as it may increase the risk of lactic acidosis.

What precautions should I take while using Oxramet XR 10mg/500mg Tablet?

Before starting this medication, inform your doctor about any kidney or liver problems you have. As advised by your doctor, regularly monitor your blood sugar levels.

What should I do if I miss a dose of Oxramet XR 10mg/500mg Tablet?

If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. In that case, skip the missed dose.

Last Updated On 25 Apr. 2025 | 6:04AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

SUN HOUSE CTS No. 201, 201, Western Express Hwy, Ram Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

DailyMed. (2024, January 15). FARXIGA- dapagliflozin tablet, film coated. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=72ad22ae-efe6-4cd6-a302-98aaee423d69
DailyMed. (2023, January 27). Metformin ER 500 mg tablet metformin ER 750 mg tablet. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b857eccf-b9ff-45ba-8241-f47f5caada2a
Bristol-Myers Squibb Company. (2014, August). FARXIGA (dapagliflozin) tablets, for oral use. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/202293s003lbl.pdf
AstraZeneca Pharmaceuticals LP. (2016, April). KOMBIGLYZE® XR (kom-be-glyze X-R)(saxagliptin and metformin HCl extended-release) tablets. U.S. Food and Drug Administration. https://www.fda.gov/downloads/drugs/drugsafety/ucm280360.pdf

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