Noltrexate 5 Tablet 10

NOLTREXATE 5 TABLET 10 is used for the following:

• Management of acute lymphoblastic leukaemia
• Dealing with breast cancer
• Handling lung cancer cases
• Addressing head and neck cancers
• Managing advanced mycosis fungoides (a type of skin cancer)
• Controlling advanced-stage non-Hodgkin's lymphomas (a variety of blood cancers)
• Assisting in severe, recalcitrant psoriasis cases not responsive to other treatments
• Handling severe, active rheumatoid arthritis in adults not adequately managed by first-line therapies

Here are some key points on how to take NOLTREXATE 5 TABLET 10:

• Follow the dosage and timing instructions provided by your doctor precisely.
• Do not change or exceed the prescribed dose without consulting your doctor.
• Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
• Adhere to the dietary recommendations given by your doctor.

NOLTREXATE 5 TABLET 10 is taken orally.

NOLTREXATE 5 TABLET 10 contains methotrexate (5 mg), which works on your body in the following ways:

• Inhibits dihydrofolate reductase: Methotrexate blocks a key enzyme in your body called dihydrofolate reductase. This enzyme is crucial for the synthesis of DNA, RNA, thymidylates, and proteins.
• Targets actively multiplying tissues: Methotrexate affects tissues that are actively growing and multiplying. These include cancer cells, bone marrow, cells in the foetus, and skin cells in psoriasis.
• Modifies immune response: In cases of rheumatoid arthritis, the exact mechanism is unclear, but methotrexate seems to alter the immune response. This action can reduce inflammation, swelling, and pain in the joints within 3-6 weeks.

• Store NOLTREXATE 5 TABLET 10 at room temperature.
• Shield the tablets from light and moisture to maintain their efficacy.
• Always keep this medicine out of children's reach.
• Use your NOLTREXATE 5 TABLET 10 before the expiry date printed on the pack.

• If you're managing rheumatoid arthritis with NOLTREXATE 5 TABLET 10, try to include omega-3 fatty acids in your diet. Foods like fish and walnuts can help reduce inflammation.
• For people using NOLTREXATE 5 TABLET 10 to manage psoriasis, avoid triggers that could cause flare-ups. These could include alcohol, stress, smoking, and certain medications. Please consult your doctor for personalised advice.