Nicomnol 3 Tablet 10

Knoll Healthcare Pvt. Ltd.

Strip of 10 Units

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MRP ~~₹101~~

₹50.4

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Composition

Nicoumalone (3 Mg)

Strength:

3 MG 4 MG 2 MG 1 MG

Nicomnol 3 Tablet 10 is used to prevent and treat harmful blood clots in your body. It belongs to a class of medications known as oral anticoagulants, specifically vitamin K antagonists.

This medicine is prescribed for conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and prevention of stroke in patients with atrial fibrillation or prosthetic heart valves. It helps reduce the risk of blood clot formation in these conditions by affecting how your blood clots.

You should take this medicine exactly as directed by your doctor, who will determine the proper dosage based on your blood test results. Before starting this medicine, inform your doctor about any pre-existing conditions or ongoing medications you may have. If you notice any unusual bleeding or other side effects while taking this medicine, contact your doctor immediately. Continue taking the medicine for the full duration prescribed by your doctor for optimal results.

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Nicomnol 3 Tablet 10 is used for the following:

Prevention of harmful blood clots
Management of deep vein thrombosis
Treatment of pulmonary embolism
Prevention of stroke in atrial fibrillation
Reducing clot risk with prosthetic heart valves
Prevention of systemic embolism
Management of thromboembolic disorders
Prevention of recurrent blood clots

Follow these instructions while taking Nicomnol 3 Tablet 10:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Take this medicine at the same time each day.
Never stop taking this medicine suddenly without consulting your doctor.

Nicomnol 3 Tablet 10 is taken orally.

Nicomnol 3 Tablet 10 may have the following common side effects:

Bleeding gums
Nosebleeds
Bruising
Petechiae: These are tiny, flat red or purple spots on the skin caused by bleeding underneath the skin surface.
Blood in urine
Blood in stool: You might notice your stools appear black, tarry or have visible red blood.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Nicomnol 3 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Bleeding gums: Taking Nicomnol 3 Tablet 10 after your evening meal may help reduce this side effect.
Bruising: Consider taking this medicine at a consistent time each day, preferably with food, to help minimise this effect.

Nicomnol 3 Tablet 10 contains nicoumalone (3 mg), which works in your body through the following mechanisms:

Vitamin K antagonism: Nicoumalone blocks the action of vitamin K, which is essential for the production of certain clotting factors in your liver. This reduces the availability of active vitamin K in your body.
Clotting factor inhibition: By reducing active vitamin K, this medicine decreases the synthesis of several clotting factors (proteins that help blood to clot). This prevents the formation of harmful blood clots in your body.
Anticoagulant effect: The medicine creates a carefully balanced state where your blood is less likely to form dangerous clots while still allowing necessary clotting for injuries. This effect is measured using a blood test called INR (International Normalised Ratio).

Pregnancy

Nicomnol 3 Tablet 10 is warned against use during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine. The active ingredient, nicoumalone, can cross the placenta and may affect your baby's development.

Breastfeeding

Caution is advised while taking Nicomnol 3 Tablet 10 if you are breastfeeding. It is best to consult your doctor before taking this medicine, as small amounts of nicoumalone may pass into breast milk.

Alcohol

Avoid consuming alcohol while taking Nicomnol 3 Tablet 10. Alcohol can interfere with how this medicine works and may increase your risk of bleeding. It may also affect your body's response to the medicine, making it harder for your doctor to maintain the right dose.

Liver

Caution is advised while taking Nicomnol 3 Tablet 10 in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Nicomnol 3 Tablet 10. This medicine may affect liver function.

Kidney

Caution is advised before using Nicomnol 3 Tablet 10 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine, as kidney function can affect how your body processes acenocoumarol.

Using Machines & Driving

You can generally drive and use machines while taking Nicomnol 3 Tablet 10. However, if you experience dizziness or unusual tiredness as side effects, avoid these activities until you feel better.

Allergy

If you have any known allergies, especially to nicoumalone or similar anticoagulants (blood thinners), inform your doctor before taking Nicomnol 3 Tablet 10. Allergic reactions can be serious and require immediate medical attention.

Children

Caution is advised while giving Nicomnol 3 Tablet 10 to children under 18 years of age. Always consult your doctor before giving any medicine to a child, as children may require special monitoring.

Older Patients

Older patients should take Nicomnol 3 Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Nicomnol 3 Tablet 10 can interact with the following medicines:

Aspirin and NSAIDs: Medicines like ibuprofen and diclofenac can increase your risk of bleeding when taken with Nicomnol 3 Tablet 10.
Antibiotics: Certain antibiotics such as erythromycin and ciprofloxacin can enhance the anticoagulant effect of Nicomnol 3 Tablet 10, potentially increasing bleeding risk.
Antifungals: Medicines like fluconazole and ketoconazole can strengthen the effect of Nicomnol 3 Tablet 10, requiring possible dosage adjustments.

Drug-Food Interactions

Nicomnol 3 Tablet 10 may interact with the following foods:

Cranberry juice: May increase the anticoagulant effect, potentially raising bleeding risk.

Drug-Disease Interactions

Nicomnol 3 Tablet 10 may interact with the following diseases:

Kidney disease: People with impaired kidney function may experience enhanced effects of Nicomnol 3 Tablet 10, requiring careful monitoring.
Liver disease: Patients with liver problems may need lower doses as the medicine's breakdown in the body could be affected.
Bleeding disorders: This medicine can worsen existing bleeding tendencies, increasing the risk of haemorrhage.

Daily Dose

The daily dose of Nicomnol 3 Tablet 10 should be taken as prescribed by your doctor. The dosage may vary based on your INR values and response to treatment. Never change your dose without consulting your doctor. Take it at the same time each day for best results.

Over Dose

Taking too much Nicomnol 3 Tablet 10 may cause unusual bleeding from gums, nose, or in urine. You might notice easy bruising, blood in stool, or prolonged bleeding from cuts. Contact your doctor if you experience these symptoms.

Missed Dose

If you forget to take Nicomnol 3 Tablet 10, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never take a double dose to make up.

Follow these instructions while storing Nicomnol 3 Tablet 10:

Store in a cool and dry place.
Keep away from direct sunlight, heat, and moisture.
Store in the original packaging until ready to use.
Keep out of reach of children and pets.
Do not use this medicine after the expiry date printed on the package.

Foods rich in vitamin K (like spinach, kale and broccoli) can affect how Nicomnol 3 Tablet 10 works. Try to keep your intake consistent rather than suddenly increasing or decreasing these foods in your diet.
Drink enough water, eat a healthy and balanced diet, and try not to make sudden changes to what you eat.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Blood clots, stroke prevention, embolism
Drug Category	Vitamin K antagonist
Therapeutic Category	Anticoagulant

What is Nicomnol 3 Tablet 10 used for?

Nicomnol 3 Tablet 10 is used to prevent and manage harmful blood clots in conditions like deep vein thrombosis, pulmonary embolism (lung clots), and to prevent stroke in patients with certain heart conditions.

How does Nicomnol 3 Tablet 10 work in the body?

It works by reducing the effect of vitamin K, which your body needs to make certain blood clotting factors. This makes your blood less likely to form harmful clots.

What precautions should I take while using Nicomnol 3 Tablet 10?

Take it at the same time daily, attend all follow-up appointments, inform your doctor about all medicines you use, and be alert for unusual bleeding or bruising signs.

What are the common side effects of Nicomnol 3 Tablet 10?

The most common side effect is increased bleeding risk. You might notice easy bruising, nosebleeds, bleeding gums, heavier periods, or blood in urine or stools.

Can I take other medicines along with Nicomnol 3 Tablet 10?

Many medicines can interact with Nicomnol 3 Tablet 10, including common painkillers, antibiotics, and herbal supplements. Always consult your doctor before taking any additional medicines.

What should I do if I forget to take Nicomnol 3 Tablet 10?

If you forget to take Nicomnol 3 Tablet 10, take it as soon as you remember. If it's nearly time for your next dose, skip the missed dose and take your next dose at the usual time. Never take a double dose.

Should I make any changes to my diet while taking Nicomnol 3 Tablet 10?

Try to maintain a consistent intake of vitamin K-rich foods (like green leafy vegetables). Sudden changes in diet can affect how well the medicine works in your body.

Last Updated On 22 May. 2025 | 9:40AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

M17, Pharma Tower,, Phase-1, Badli Industrial Area,, Badli, Delhi, 110042

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Brafield, A. J. (1959). Nicoumalone: a new anticoagulant. BMJ, 1(5131), 1211–1213. https://doi.org/10.1136/bmj.1.5131.1211
Gill, T., Hopkins, K., Bottomley, J., Gupta, S., & Rowland, M. (1989). Cimetidine‐nicoumalone interaction in man: stereochemical considerations. British Journal of Clinical Pharmacology, 27(4), 469–474. https://doi.org/10.1111/j.1365-2125.1989.tb05395.x
PubChem. (n.d.-b). Acenocoumarol. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Acenocoumarol
GSRS. (n.d.). https://precision.fda.gov/ginas/app/ui/substances/4d740889-9720-4cb0-bc8c-f4c6934305ef
Behera, S. K., Xavier, A. S., Selvarajan, S., Munuswamy, H., Haridasan, S., & Srinivas, B. H. (2018). Acenocoumarol as an alternative anticoagulant in a patient with warfarin‐related nephropathy. British Journal of Clinical Pharmacology, 84(5), 1068–1071. https://doi.org/10.1111/bcp.13541
Acenocoumarol: A review of anticoagulant efficacy and safety. (2016, February 1). PubMed. https://pubmed.ncbi.nlm.nih.gov/27730796/

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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