Esofine Dsr Capsule 15

Macleods Pharmaceuticals Pvt.ltd

STRIP of 10 Units
STRIP of 15 Units

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MRP ~~₹222.75~~

₹178.2

₹14.85/Units

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Composition

Domperidone (30 Mg) + Esomeprazole (40 Mg)

Esofine Dsr Capsule 15 is used to treat gastroesophageal reflux disease (GERD) and acidity-related conditions. It contains esomeprazole and domperidone, which reduce stomach acid production and improve gastric motility. This combination medicine belongs to a group of medications known as proton pump inhibitors (PPIs) and prokinetics.

In addition to managing GERD and indigestion, this medicine can also offer relief from symptoms such as heartburn, stomach pain, and irritation. By neutralising stomach acid and facilitating the passage of gas, it helps reduce discomfort in the stomach. The medicine also manages functional dyspepsia by enhancing the rate at which the stomach empties.

The dosage and frequency of this medicine should be strictly as directed by your doctor. It is important to notify your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while on this medicine, inform your doctor immediately. For optimal results, continue taking the medicine for the period prescribed by your doctor.

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Esofine Dsr Capsule 15 is used to treat GERD, acidity, heartburn, stomach ulcers, bloating, nausea, belching, and upper abdominal pain by reducing acid production and improving stomach movement.

Here's how you should take Esofine Dsr Capsule 15:

Swallow the capsule whole with a glass of water. Avoid breaking, chewing, or dissolving it.
Always consume this medicine on an empty stomach for best results.
Continue taking this medication for as long as your doctor advises. If you stop the medicine too soon, your symptoms may come back.
Do not take Esofine Dsr Capsule 15 with other medications that affect stomach acid within 30 minutes of each other.

Esofine Dsr Capsule 15 is taken orally.

The following are the typical side effects you could experience while taking Esofine Dsr Capsule 15:

Diarrhoea
Flatulence
Stomach pain
Dry mouth
Headache

These side effects are usually temporary and should subside on their own. However, if they persist or cause severe discomfort, make sure to inform your doctor.

Managing the Side Effects:

Most side effects are temporary, usually mild, and resolve upon suspending the use of Esofine Dsr Capsule 15. However, if you experience serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some guidelines to manage two common side effects:

Diarrhoea: Try taking Esofine Dsr Capsule 15 with food. It can slow down digestion and help mitigate this effect.
Stomach pain: If you experience stomach pain, consider taking this medicine after meals rather than before. This could lessen the impact on your stomach lining.

Esofine Dsr Capsule 15 has two active ingredients:

Domperidone (30 mg): Being a prokinetic, domperidone works by enhancing motility in the upper part of your digestive tract. It increases stomach and intestinal movement, which helps food pass through more easily.
Esomeprazole (40 mg): This ingredient belongs to the class of proton pump inhibitors (PPIs). It decreases stomach acid production, helping manage acid-related indigestion and heartburn.

Pregnancy

If you are pregnant or planning to conceive, take Esofine Dsr Capsule 15 with caution. Consult your doctor before starting this medicine.

Breastfeeding

Esofine Dsr Capsule 15 is considered safe during breastfeeding. However, inform your doctor that you are breastfeeding if this medicine is prescribed to you.

Alcohol

Exercise caution when consuming alcohol while taking Esofine Dsr Capsule 15. While alcohol does not directly affect the working of the medicine, it can trigger stomach acid production and exacerbate your condition.

Liver

If you have any liver health concerns, exercise caution before using Esofine Dsr Capsule 15. This medicine should be avoided in cases of moderate to severe liver impairment.

Kidney

For those with a history of kidney issues, caution is recommended when starting Esofine Dsr Capsule 15. It is advisable to consult a doctor.

Using Machines & Driving

Esofine Dsr Capsule 15 may cause drowsiness and dizziness. So, be careful while driving or operating heavy machinery until you know how this medicine affects you.

Allergy

Esofine Dsr Capsule 15 is contraindicated if you have a known hypersensitivity to proton pump inhibitors. Always inform your doctor if you have any allergies.

Children

Esofine Dsr Capsule 15 is not recommended for children under 18 years of age. It's always best to consult a doctor before giving any medicine to a child.

Older Patients

Older patients should use Esofine Dsr Capsule 15 under medical supervision, as they could be more susceptible to its side effects. If you are over 70 years of age, consult your doctor for guidance.

Drug-Drug Interactions

Esofine Dsr Capsule 15 interacts with the following medicines:

Antiretrovirals: This medicine might interact with HIV medications like ritonavir or atazanavir and could potentially affect their effectiveness.
Anticoagulants: Medications such as clopidogrel, which helps prevent blood clots, might interact with Esofine Dsr Capsule 15, potentially altering their effects.
Immunosuppressants: This medicine can affect the levels of tacrolimus, a medicine used to reduce the immune response in transplants.
Anti-tubercular medications: Rifampin, used to manage tuberculosis, could potentially interact with Esofine Dsr Capsule 15, possibly affecting its absorption.

Drug-Food Interactions

Esofine Dsr Capsule 15 has some known interactions with food:

Grapefruit juice: Consuming grapefruit juice while taking this medicine might increase its absorption, potentially leading to increased side effects.

Drug-Disease Interactions

Esofine Dsr Capsule 15 interacts with the following diseases:

Liver disease: If you have liver disease, you should exercise caution, as this medicine could potentially worsen your condition.
Kidney disease: People with kidney disease should also be careful, as this capsule might impact their condition.

Daily Dose

The recommended dose of Esofine Dsr Capsule 15 should be taken as prescribed by your doctor. The dosage may vary depending on the severity of your symptoms and how well you respond to the medicine. Always follow the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

In cases of overdose, you may experience common side effects such as stomach pain, diarrhoea, or headaches in a more severe form. If you accidentally take more than the prescribed dose, consult your doctor for advice.

Missed Dose

If you miss a dose of Esofine Dsr Capsule 15, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Never adjust your dosage without consulting your doctor.

Store Esofine Dsr Capsule 15 in a cool, dry place.
Avoid exposure to direct sunlight, excessive heat, and moisture.
Keep this medicine out of reach of children.
Always check the expiry date on the pack and make sure you use the medicine before that date.

For managing gastroesophageal reflux disease (GERD), avoid spicy and fatty foods, as they can trigger heartburn.
Regular physical activity can improve digestion and reduce symptoms like bloating or discomfort associated with functional dyspepsia. Avoid heavy exercise right after meals, as it may worsen acid reflux.

Fact Box

Available Dosage Types	Capsule
Habit Forming	No
Ailment	Gastroesophageal Reflux Disease, Indigestion
Drug Category	Prokinetic, Proton Pump Inhibitor
Therapeutic Category	Gastrointestinal

What is Esofine Dsr Capsule 15 used for?

This medicine reduces stomach acid and aids in digestion, managing gastroesophageal reflux disease (GERD) and indigestion.

How does Esofine Dsr Capsule 15 work?

It works by combining the effects of two ingredients, domperidone enhances movement in the digestive tract, and esomeprazole reduces the production of stomach acid.

Can Esofine Dsr Capsule 15 cause drowsiness or dizziness?

Yes, it may cause these side effects. If you experience them, avoid driving or activities that require alertness until you know how the medicine affects you.

Should I inform my doctor if I'm pregnant or breastfeeding before taking Esofine Dsr Capsule 15?

Yes, always inform your doctor about your pregnancy or breastfeeding status before starting on this medication.

What should I do if I miss a dose of Esofine Dsr Capsule 15?

If you miss a dose, take it when you can. However, if it's nearly time for your next dose, skip the missed dose and continue with your regular schedule.

Can I consume alcohol while taking Esofine Dsr Capsule 15?

Caution should be exercised while consuming alcohol while taking this medication; consult your doctor for detailed advice.

How should I store Esofine Dsr Capsule 15?

As directed by your doctor, store the medicine in a cool, dry place, out of the reach of children.

Last Updated On 13 May. 2025 | 11:15AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Osama Ahmed

Medical Content Writer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Atlanta Arcade, Marol Church Rd, Bori Colony, Vijay Nagar Colony West, Marol, Andheri East, Mumbai, Maharashtra 400059

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

U.S. Food and Drug Administration. (2021). Nexium (esomeprazole) label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/021153s056,021957s023,022101s020lbl.pdf
MedlinePlus. (2023, Nov 15). Esomeprazole. https://medlineplus.gov/druginfo/meds/a699054.html
U.K. National Health Services. (n.d.). Domperidone. https://www.nhs.uk/medicines/domperidone/
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 9568614, Esomeprazole. https://pubchem.ncbi.nlm.nih.gov/compound/Esomeprazole
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 3151, Domperidone. https://pubchem.ncbi.nlm.nih.gov/compound/Domperidone
DrugBank Online. (2024, May 30). Esomeprazole. https://go.drugbank.com/drugs/DB00736
DrugBank Online. (2024, May 30). Domperidone. https://go.drugbank.com/drugs/DB01184

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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