Eplebless 25 Tablet 10

Mankind Pharmaceuticals Ltd.

Strip of 10 Units

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Old MRP ₹180.29

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₹135.22

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Composition

Eplerenone (25 Mg)

Strength:

50 MG 25 MG

Eplebless 25 Tablet is used to manage high blood pressure and heart failure. It removes extra water from the body without losing potassium, helping reduce swelling and strain on the heart. This supports healthier blood pressure and better heart function. It belongs to a category of medicines known as potassium-sparing diuretics.

This medicine is also used to control high blood pressure, either on its own or in combination with other blood pressure medications. By managing these conditions, it contributes to the overall health of your heart and circulatory system.

Before you start taking this medicine, consult your doctor about your current health condition and any other medicines you are taking. If you notice any side effects while taking this medicine, inform your doctor promptly. Remember, for the best results, continue taking this medicine for the entire duration prescribed by your doctor.

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Eplebless 25 Tablet is used to treat high blood pressure and heart failure. It helps reduce fluid retention, lower blood pressure, and protect the heart by blocking certain hormones.

Swallow the tablet whole with a glass of water.
Avoid breaking, chewing or crushing the tablet.
Always follow your doctor's instructions about dosage.
Don't alter the dose or stop taking the medicine without consulting your doctor.

Eplebless 25 Tablet is taken orally.

Eplebless 25 Tablet may have the following common side effects:

Headache
Dizziness
Diarrhoea
Nausea
Vomiting
Abdominal pain
Fatigue

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Eplebless 25 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:

Diarrhoea: Consume plenty of water and healthy fluids to avoid dehydration.
Abdominal pain: If you experience this discomfort after taking the medicine, consider having it after meals.

Eplebless 25 Tablet contains Eplerenone (25 mg). Here's how it works in your body:

Blocks Aldosterone: Eplerenone blocks the action of a hormone called aldosterone. Aldosterone controls the balance of water and salts in your body.
Reduces Blood Volume and Pressure: By blocking aldosterone, Eplerenone helps remove excess water from your body. This reduces the volume of your blood, which in turn lowers your blood pressure.
Relaxes Blood Vessels: Eplerenone also helps relax your blood vessels, which further contributes to lowering blood pressure.
Increases Urine Production: Eplerenone increases the amount of urine your body produces, helping to remove excess water and salt from your body.
Maintains Potassium Levels: By keeping the correct amount of potassium in your bloodstream, Eplerenone helps prevent heart failure from getting worse.

Pregnancy

Caution is advised while taking Eplebless 25 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Eplebless 25 Tablet is recommended for use in breastfeeding women only when clearly needed. Consult your doctor if you are breastfeeding.

Alcohol

Limit alcohol consumption while taking this medication, as it may increase dizziness.

Liver

Caution is advised while taking Eplebless 25 Tablet in case of liver impairment. If you have liver problems, discuss them with your doctor before starting this medicine.

Kidney

Caution is advised before using Eplebless 25 Tablet if you have a history of kidney problems. It's good to consult your doctor before taking this medicine.

Using Machines & Driving

Eplebless 25 Tablet may cause dizziness. Avoid driving, operating machinery, or performing tasks that require alertness until you know how the medication affects you.

Allergy

Inform your doctor about any allergies you have, especially to eplerenone or any other medications before starting to take Eplebless 25 Tablet.

Children

Caution is advised while giving Eplebless 25 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Eplebless 25 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Eplebless 25 Tablet interacts with the following medicines:

Antifungals: Medicines such as ketoconazole and itraconazole can increase Eplerenone's effect. This could potentially cause an increase in your potassium levels.
Antihypertensives: If you're taking medicines like lisinopril or losartan, they might increase the risk of high levels of potassium in your blood when taken with Eplebless 25 Tablet.
NSAIDs: Medicines like ibuprofen or naproxen, when taken with Eplebless 25 Tablet, may increase the risk of high potassium levels and kidney damage.

Drug-Food Interactions

There are no specific food items known to interact with Eplebless 25 Tablet.

Drug-Disease Interactions

Eplebless 25 Tablet interacts with the following diseases:

High Potassium Levels: If you have high potassium levels (hyperkalemia), taking Eplebless 25 Tablet can worsen your condition due to its potassium-sparing effect.
Kidney Disease: The medicine could potentially worsen kidney disease because of its diuretic properties.
Liver Disease: People with liver disease might need dose adjustments due to reduced liver function affecting the metabolism of Eplerenone.
Diabetes: Changes in water balance due to the diuretic effect of this medicine could potentially affect blood sugar control.

Daily Dose

Your doctor will prescribe the appropriate daily dosage of Eplebless 25 Tablet for you. The dosage will be determined by factors like your health condition and how well you respond to the medicine. It's crucial that you follow your doctor's instructions and not alter your dose without consulting them.

Over Dose

In case you take more Eplebless 25 Tablet than prescribed, you may experience common side effects like headache, dizziness, or stomach discomfort. If such symptoms persist or worsen, inform your doctor promptly.

Missed Dose

If you've missed a dose of Eplebless 25 Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. It's important not to increase your dose without consulting your doctor.

Keep Eplebless 25 Tablet in a cool, dry place where the temperature stays below 30°C.
Protect it from direct sunlight and excessive heat.
Do not store this medicine in damp places such as bathrooms.
Always keep Eplebless 25 Tablet out of reach of children.
Use it before the expiry date mentioned on the package.

If you have high blood pressure or heart failure, limit your salt intake. Eating less salt can help manage these conditions along with taking Eplebless 25 Tablet.
Regular exercise, like walking or cycling, can contribute to managing your blood pressure levels. However, consult your doctor for the best type of exercise suitable for your condition.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Heart Failure, Hypertension
Drug Category	Aldosterone Receptor Antagonist
Therapeutic Category	Antihypertensive

What is Eplebless 25 Tablet used for?

This medicine helps manage high blood pressure and heart failure by reducing excess water in your body.

How does Eplebless 25 Tablet work?

It blocks a hormone called aldosterone, which helps decrease blood volume and pressure, removing excess salt and water from your body.

How should I take Eplebless 25 Tablet?

Swallow the tablet whole with water. You can take it with or without food, but make sure to take it at the same time each day.

What if I miss a dose of Eplebless 25 Tablet?

If you miss a dose, take it as soon as you remember. If it's nearly time for the next dose, skip the missed one.

Can I stop taking Eplebless 25 Tablet if my blood pressure is under control?

Do not stop taking this medicine without consulting your doctor as your blood pressure could rise again or worsen your heart symptoms.

Are there any side effects of Eplebless 25 Tablet?

Common side effects include headache, dizziness, diarrhoea, nausea, vomiting, abdominal pain, and fatigue. Speak to your doctor if these persist or worsen.

Are there any precautions I should follow while taking Eplebless 25 Tablet?

Avoid driving if you experience dizziness after taking this medicine. Limit alcohol intake as it could increase dizziness. Always inform your doctor about any allergies or medical conditions you have.

Last Updated On 22 Sep. 2025 | 10:39AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

208, Okhla Industrial Estate, Phase-III, New Delhi South Delhi DL 110020 IN

Country of origin: INDIA

Expiry on or after: March 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Pfizer Inc. (2016). Highlights of prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021437s013lbl.pdf
DailyMed - EPLERENONE- eplerenone tablet, film coated. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=25a1c77c-7008-4b07-af14-5522a282783a
Eplerenone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00700
Eplerenone: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a603004.html

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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CIN: U62099MH2019PTC320566

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