Eplegino 25 Tablet 10 is used to manage high blood pressure and heart failure, and to support recovery after a heart attack. It reduces fluid retention and eases the strain on the heart.
It contains eplerenone, which blocks aldosterone, a hormone that makes the body hold on to salt and water. This lowers blood pressure and helps the heart.
Take it as prescribed, at the same time each day.
Because it can raise potassium, tell your doctor about any kidney problems, and avoid potassium supplements or salt substitutes unless advised. Your doctor may check your potassium and kidney function.
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Eplegino 25 Tablet 10
Kureasia Pharma Private Limited
Strip of 10 Units
MRP ₹325
₹162.5
₹16.25/Units
50% off
*MRP inclusive of all taxes100% genuine medicines
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15 days Easy returns
Prescription required for this medicine
Store Below 30° C
CompositionAbout Eplegino 25 Tablet 10
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Uses of Eplegino 25 Tablet 10
Eplegino 25 Tablet 10 is used for high blood pressure and heart failure.
Uses of Eplegino 25 Tablet 10 are:
- High Blood Pressure: Helps lower blood pressure by reducing fluid retention.
- Heart Failure: Helps support heart function and reduce fluid overload.
- After a Heart Attack: Helps reduce complications after a heart attack.
Directions for Use of Eplegino 25 Tablet 10
Take the tablet whole with a full glass of water.
You may take this medicine with or without food.
Do not crush or chew the tablet.
Take this medicine at the same time each day to maintain its effect.
Continue taking this medicine for as long as your doctor advises.
Do not stop taking this medicine without consulting your doctor.
Route of Administration
Eplegino 25 Tablet 10 is taken orally.
Side Effects of Eplegino 25 Tablet 10
Eplegino 25 Tablet 10 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.
A few common side effects of Eplegino 25 Tablet 10:
- Blood Salts: Raised potassium levels; your doctor may check this with blood tests.
- Nervous System: Dizziness and headache.
- General: Tiredness, loose motions (diarrhoea) and muscle cramps.
If side effects do not improve or become serious, speak to your doctor right away.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Eplegino 25 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some tips for managing common side effects:
Nausea: Taking Eplegino 25 Tablet 10 with food can help reduce feelings of sickness.
Dizziness: Consider taking this medicine at bedtime if it makes you feel dizzy during the day.
How Eplegino 25 Tablet 10 Works?
Eplegino 25 Tablet 10 contains eplerenone (25 mg), which works on the body as follows:
Blocks Mineralocorticoid Receptors: Eplerenone selectively blocks receptors for a hormone called aldosterone in your kidneys and blood vessels. This blocking action prevents aldosterone from causing harmful effects on your heart and blood pressure.
Reduces Sodium and Water Retention: By blocking aldosterone's effects, eplerenone helps your body get rid of excess sodium and water through urine. This reduction in fluid volume helps lower your blood pressure.
Preserves Potassium: Unlike some other diuretics (water pills), eplerenone helps your body retain potassium rather than lose it. This is why it's called a "potassium-sparing" diuretic.
Decreases Heart Workload: By reducing fluid volume and blood pressure, eplerenone decreases the strain on your heart, which is especially beneficial after a heart attack.
Safety Measures & Warnings
Pregnancy
Caution is advised while taking Eplegino 25 Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.
Breastfeeding
Exercise caution while taking Eplegino 25 Tablet 10 if you are breastfeeding. It is best to consult your doctor before taking this medicine.
Alcohol
Take caution when consuming alcohol while on Eplegino 25 Tablet 10. Alcohol might increase your risk of dizziness and other side effects. Discuss your alcohol consumption habits with your doctor.
Liver
Caution is advised while taking Eplegino 25 Tablet 10 if you have severe liver problems. This medicine is not recommended for patients with severe liver dysfunction. Your doctor should assess your liver function before prescribing this medicine.
Kidney
Eplegino 25 Tablet 10 is warned against use if you have severe kidney insufficiency. Your doctor will need to check your kidney function before and during treatment with this medicine, as it affects how your body processes potassium.
Use In Driving And Operating Machinery
You may experience dizziness while taking Eplegino 25 Tablet 10. If you notice this effect, avoid driving vehicles or operating heavy machinery until you feel better. These activities require full alertness for safety.
Allergy
If you have any known allergies to eplerenone or other ingredients in Eplegino 25 Tablet 10, do not take this medicine. Tell your doctor about all your allergies before starting treatment to avoid hypersensitivity reactions.
Children
Caution is advised while giving this medicine to children under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older Patients
Older patients should take this tablet under medical supervision, as they may be more susceptible to side effects, especially high potassium levels. Your doctor will monitor your potassium levels regularly and may adjust the dosage based on your kidney function.
Interactions of Eplegino 25 Tablet 10
Drug-Drug Interactions
Eplegino 25 Tablet 10 can interact with the following medicines:
CYP3A4 inhibitors: Strong inhibitors like ketoconazole and itraconazole may increase eplerenone levels in your blood, raising the risk of side effects.
ACE inhibitors: Medicines such as lisinopril and enalapril can increase the risk of high potassium levels (hyperkalaemia) when taken with Eplegino 25 Tablet 10.
Angiotensin receptor blockers (ARBs): Medicines like losartan and valsartan may increase potassium levels when used alongside Eplegino 25 Tablet 10.
Potassium-sparing diuretics: Medicines such as spironolactone and amiloride can dangerously increase potassium levels when combined with Eplegino 25 Tablet 10.
NSAIDs: Anti-inflammatory medicines like ibuprofen and diclofenac may reduce Eplegino 25 Tablet 10's blood pressure-lowering effects.
Lithium: Eplegino 25 Tablet 10 may increase lithium concentration in your blood, potentially leading to lithium toxicity.
Drug-Disease Interactions
Eplegino 25 Tablet 10 may interact with the following diseases:
Kidney impairment: Eplegino 25 Tablet 10 may increase potassium levels in patients with reduced kidney function, especially if eGFR is below 30 mL/min.
Diabetes: Diabetic patients taking Eplegino 25 Tablet 10 have a higher risk of developing high potassium levels in their blood.
High potassium levels: Eplegino 25 Tablet 10 can further increase potassium levels if you already have high potassium (above 5.5 mEq/L).
Dosage of Eplegino 25 Tablet 10
Daily Dose
The daily dose of Eplegino 25 Tablet 10 should be taken as prescribed by your doctor. The dosage may change based on your condition's severity and how you respond to treatment. Always follow the prescribed dosage and never exceed it without consulting your doctor.
Over Dose
Taking too much of this medication may cause dizziness, severe headache, nausea, or unusually high potassium levels in your blood. If you experience these symptoms after taking extra tablets, consult your doctor promptly for advice.
Missed Dose
If you forget to take Eplegino 25 Tablet 10, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and resume your regular schedule. Never increase your dosage without consulting your doctor.
Storage
Store Eplegino 25 Tablet 10 at room temperature below 30°C.
Keep the medicine protected from moisture and light.
Store in the original packaging to maintain quality.
Keep out of reach of children.
Do not use this medicine after the expiry date printed on the package.
Discard any unused medicine properly.
Special Dietary And Lifestyle Recommendation
Reduce your salt intake, as high sodium consumption can worsen high blood pressure and put extra strain on your heart. Try using herbs and spices instead of salt to flavour your food.
Consider following the DASH diet (Dietary Approaches to Stop Hypertension), which emphasises fruits, vegetables, whole grains, and low-fat dairy products to help manage blood pressure naturally.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Hypertension, heart failure |
| Drug Category | Mineralocorticoid receptor antagonist |
| Therapeutic Category | Antihypertensive |
Frequently Asked Questions (FAQs)
How long does it take for Eplegino 25 Tablet 10 to work?
You may notice initial effects within 1-2 weeks, but full blood pressure benefits typically appear after 4 weeks of regular use.
Can I take Eplegino 25 Tablet 10 with food?
Yes, you can take this medicine with or without food. Taking it with meals may help reduce stomach discomfort if you experience it.
What should I do if I miss a dose?
Take it when you remember, unless it's nearly time for your next dose. In that case, skip the missed dose and continue your regular schedule.
Can I stop taking Eplegino 25 Tablet 10 suddenly?
No, don't stop taking this medicine without consulting your doctor first. Sudden discontinuation may cause your blood pressure to rise quickly.
Will Eplegino 25 Tablet 10 affect my potassium levels?
Yes, this medicine can increase potassium levels in your blood. Your doctor will likely monitor these levels regularly during treatment.
What side effects might I experience?
Common side effects include dizziness, headache, feeling tired, nausea, and diarrhoea. Most side effects are mild and improve with time.
Can I take other medicines with Eplegino 25 Tablet 10?
Some groups of medications, such as potassium-sparing diuretics, angiotensin receptor blockers, and ACE inhibitors may interact with eplerenone. Always inform your doctor about all medicines you're currently taking before starting Eplegino 25 Tablet 10.
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Manufacturer details
3rd Floor, B, 255, Munshi Ram Gupta Marg, Industrial Area Phase I, Block B, Naraina Industrial Area Phase 1, Naraina, New Delhi, Delhi 110028
Country of origin: INDIA
Country of origin: INDIA
Expiry on or after: February 2027
In case of any issues, contact us:
support@truemeds.in|09240250346
Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071
References
Eplerenone: MedlinePlus drug information. (n.d.-b). https://medlineplus.gov/druginfo/meds/a603004.html
DailyMed - EPLERENONE tablet, film coated. (n.d.-b). https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=e2a51c12-bdc2-4b3b-8e9e-bf363c2817ed
Hughes, J. C., & Cassagnol, M. (2023, May 1). Eplerenone. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK553100/
PubChem. (n.d.-ac). Eplerenone. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Eplerenone
U.S. Food and Drug Administration. (2016). Highlights of prescribing information: Eplegino 25 Tablet 10 (tablet) [Label]. Retrieved 1 April 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021437s013lbl.pdf
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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Intellihealth Solutions Private Limited
Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.
CIN: U62099MH2019PTC320566
Telephone:09240250346
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