Duopil 2/500 Tablet 10

Duopil 2/500 Tablet is used in the long-term management of type 2 diabetes in adults.

Uses of Duopil 2/500 Tablet are:

• Blood Sugar Control: Improves glycaemic control in adults with type 2 diabetes.
• Combination Therapy: Helps those who have not achieved adequate control with a single medicine.

Here's how to take Duopil 2/500 Tablet properly:

• Follow the dosage and timing instructions provided by your doctor precisely.

• Do not change or exceed the prescribed dose without consulting your doctor.

• Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.

• Adhere to the dietary recommendations given by your doctor.

Duopil 2/500 Tablet is taken orally.

Duopil 2/500 Tablet comprises two active ingredients:

• Glimepiride (2 mg): As a sulfonylurea, glimepiride interacts with the sulfonylurea receptors located on pancreatic beta cells. Here, it closes potassium channels that are dependent on ATP (adenosine triphosphate), a process known as depolarisation. This action stimulates insulin release from these cells, enhancing both the initial and secondary phases of insulin secretion.

• Metformin (500 mg): Classified as a biguanide, metformin works by reducing glucose production in your liver and slowing down glucose absorption from your intestines—processes known as gluconeogenesis and glycogenolysis respectively. Additionally, it improves insulin sensitivity by aiding peripheral glucose uptake and utilisation. The extended-release formulation allows for gradual and sustained absorption of metformin, resulting in more controlled glycemic management and fewer gastrointestinal side effects.

• Store Duopil 2/500 Tablet ideally at a temperature below 30°C.

• Keep this medicine away from light and moisture.

• Make sure to keep it out of the reach and sight of children.

• Always check the expiry date before using Duopil 2/500 Tablet.

• Stick to a balanced diet that's low in sugar and fats. This helps control your blood sugar levels, complementing the effectiveness of Duopil 2/500 Tablet.

• Regular physical activity, such as walking or yoga, helps in managing type 2 diabetes by improving insulin sensitivity and controlling blood glucose levels.