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Volix Trio 2 Tablet is used to treat uncontrolled type 2 diabetes in adults. This oral antidiabetic combination uses glimepiride, metformin, and voglibose (an alpha-glucosidase inhibitor). This triple-medication therapy works synergistically to stimulate insulin release, reduce hepatic glucose, and notably, slow down carbohydrate absorption in the intestines, ensuring efficient control of blood glucose levels.
Volix Trio 2 Tablet is used for the comprehensive management of type 2 diabetes mellitus in adults, combining actions to increase insulin secretion, reduce hepatic glucose production, and delay carbohydrate absorption to control persistently high blood sugar levels and postprandial spikes.
Follow these instructions while taking Volix Trio 2 Tablet:
Swallow the tablet whole with a sufficient amount of water.
Do not split, crush, or chew the tablet.
For any specific advice related to your dosage or time of administration, consult your doctor.
Volix Trio 2 Tablet is taken orally.
Common side effects of Volix Trio 2 Tablet include hypoglycemia (low blood sugar), gastrointestinal symptoms (diarrhoea, nausea, vomiting, abdominal pain), headache, dizziness, vitamin B12 deficiency, and skin reactions.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Volix Trio 2 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Diarrhoea: Try taking Volix Trio 2 Tablet with food.
Hypoglycaemia: If you notice symptoms like dizziness or shaking, consider having a small snack containing sugar.
Volix Trio 2 Tablet contains three active ingredients:
Glimepiride (2 mg): This sulfonylurea stimulates your pancreas to secrete more insulin, which helps lower your blood glucose levels. It also enhances your body's sensitivity to insulin, amplifying its effectiveness.
Metformin Hydrochloride (500 mg): This biguanide works by reducing the production of glucose in your liver, increasing the uptake and use of glucose in your body's peripheral tissues, and enhancing your body's sensitivity to insulin. It is worth noting that when used alone, metformin doesn't lead to hypoglycaemia or low blood sugar.
Voglibose (0.2 mg): As an alpha-glucosidase inhibitor, voglibose slows down the breakdown and absorption of carbohydrates in your intestine, thus reducing the spike in blood glucose levels after meals.
Volix Trio 2 Tablet is not recommended during pregnancy unless clearly needed. You should consult your doctor before taking this medicine if you are pregnant.
It's advisable to consult your doctor before taking this medicine if you are nursing a baby.
Alcohol may increase the risk of lactic acidosis, a rare but serious side effect of metformin, one of the components in Volix Trio 2 Tablet. It's best to limit alcohol consumption while taking this medicine and discuss any concerns with your doctor.
As with any medicine, caution is advised when taking Volix Trio 2 Tablet if you have liver problems. Discuss your liver health issues with your doctor before starting this medication.
Volix Trio 2 Tablet is contraindicated in patients with severe kidney impairment. If you have a history of kidney problems, it's important to consult your doctor before starting this medication.
This medication can cause low blood sugar (hypoglycemia), which may affect your ability to drive or operate machinery. Be cautious if you're driving or doing anything that requires alertness until you know how this medicine affects you.
If you are allergic to glimepiride, metformin, voglibose, or any other ingredients in Volix Trio 2 Tablet, discuss this with your doctor before starting treatment.
This medication is not recommended for use in children under 18 years of age. Always consult your doctor before giving any medication to a child.
Older patients may be more susceptible to side effects of Volix Trio 2 Tablet and might also have liver and kidney issues. If you are above 70 years of age, you should take this medication under medical supervision. Your doctor will guide you based on your health status.
Volix Trio 2 Tablet interacts with the following medicines:
Beta-blockers: Medicines such as propranolol or atenolol may hide signs of low blood sugar, which is a side effect of Volix Trio 2 Tablet.
Thiazides and corticosteroids: Medicines like hydrochlorothiazide or prednisone may cause high blood sugar and interfere with the glucose-lowering effect of Volix Trio 2 Tablet.
ACE inhibitors: Medicines like enalapril or lisinopril can increase the blood sugar-lowering effect of glimepiride, a component of Volix Trio 2 Tablet.
Carbonic anhydrase inhibitors and topiramate: These medicines, including acetazolamide and zonisamide, can increase the risk of lactic acidosis when taken with metformin, a component of Volix Trio 2 Tablet.
Volix Trio 2 Tablet has interactions with certain foods:
High fibre foods: These may decrease the absorption rate of metformin, a component of Volix Trio 2 Tablet, thereby reducing its effectiveness.
Volix Trio 2 Tablet interacts with the following diseases:
Kidney disease: The medicine may not be fully excreted from the body in patients with kidney disease, causing harmful levels to build up.
Liver disease: Liver issues can alter the effectiveness and side effect profile of this medicine.
Heart failure: The metformin in the medicine could worsen heart function in people with this condition.
Your daily dose of Volix Trio 2 Tablet will be decided by your doctor. This varies based on your condition's severity and your reaction to the medication.
If you take too much Volix Trio 2 Tablet, you might experience symptoms like nausea, diarrhoea or stomach pain. If these symptoms persist or worsen, inform your doctor.
Missed a dose? Take it as soon as you remember. If it's nearly time for the next one, skip the missed dose. Never increase your dosage without consulting your doctor.
Store your Volix Trio 2 Tablet in a cool, dry place where the temperature stays between 15-30°C.
Keep it away from direct sunlight and moisture.
Make sure the container is tightly closed after use.
Always keep this medicine out of reach of children.
Use the Volix Trio 2 Tablet before its expiry date.
Eating a balanced diet with low sugar content can support the management of your type 2 diabetes. Foods rich in fibre like fruits, vegetables, and whole grains may be beneficial.
Regular physical activity such as walking, cycling, or swimming can help manage your blood glucose levels. Make sure to consult with your doctor before starting any new exercise regimen.
| Available Dosage Types | Tablet ER |
| Habit Forming | No |
| Ailment | Type 2 Diabetes Mellitus |
| Drug Category | Sulfonylurea, Biguanide, Alpha-glucosidase Inhibitor |
| Therapeutic Category | Antidiabetic |
It's an oral medicine used to manage type 2 diabetes in adults, alongside diet and exercise.
This medicine combines three active ingredients: glimepiride stimulates insulin release, metformin reduces liver glucose production, and voglibose slows carbohydrate breakdown.
It should be taken with meals, as directed by your doctor.
Common side effects include hypoglycaemia, gastrointestinal symptoms like diarrhoea and nausea, headache, dizziness, vitamin B12 deficiency, and skin reactions.
Yes, inform your doctor about all other medicines you're taking as they might interact with Volix Trio 2 Tablet.
No, discontinuing the medicine abruptly can cause blood sugar levels to rise. Always consult your doctor before making any changes.
You should consult your doctor before using it during pregnancy.
Check out Editorial Policy
Metformin - StatPearls - NCBI bookshelf. (2023, August 17). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK518983/
Langtry, H. D., & Balfour, J. A. (1998). Glimepiride. A review of its use in the management of type 2 diabetes mellitus. Drugs, 55(4), 563–584. Retrieved 24 October 2024, from https://doi.org/10.2165/00003495-199855040-00007
Dutta, S., Shah, R. B., Singhal, S., Dutta, S. B., Bansal, S., Sinha, S., & Haque, M. (2023). Metformin: A review of potential mechanism and therapeutic utility beyond diabetes. Drug Design, Development and Therapy, 17, 1907–1932. Retrieved 24 October 2024, from https://doi.org/10.2147/DDDT.S409373
Glimepiride: Medicine to treat type 2 diabetes. (2022, March 17). Nhs.Uk. Retrieved 24 October 2024, from https://www.nhs.uk/medicines/glimepiride/
Voglibose. (n.d.). Retrieved 24 October 2024, from https://go.drugbank.com/drugs/DB04878
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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