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Glyciphage-VG2 Tablet is a triple-combination medicine used to treat Type 2 Diabetes Mellitus. It belongs to the class of oral antidiabetic medicines (combining Metformin, Glimepiride, and Voglibose). This comprehensive approach enhances insulin sensitivity, reduces excess liver-produced glucose, and, crucially, delays carbohydrate absorption in the gut, collectively providing powerful control over blood sugar levels.
Glyciphage-VG2 Tablet is used to regulate blood sugar levels in type 2 diabetes. It helps control high blood sugar levels in adults with type 2 diabetes and enhances the effectiveness of diet and exercise when they alone are not enough.
Always swallow the whole tablet with a glass of water. Crushing or chewing it can interfere with its sustained release action.
For optimal absorption, take it with your first main meal of the day.
Remember, it's important to follow the dose recommended by your doctor. If you're unsure about how many tablets to take, consult your doctor.
Lastly, please do not stop using this medicine abruptly without speaking to your doctor first.
Glyciphage-VG2 Tablet is taken orally.
Glyciphage-VG2 Tablet may cause hypoglycemia, nausea, diarrhea, abdominal discomfort, and weight gain.
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of the Glyciphage-VG2 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Hypoglycaemia: Always carry a fast-acting source of glucose with you to manage sudden drops in blood sugar.
Abdominal discomfort: Try taking Glyciphage-VG2 Tablet with your first main meal to lessen this effect.
Glyciphage-VG2 Tablet consists of the following components:
Glimepiride (2 mg): Glimepiride belongs to a class of medication known as sulfonylureas. It encourages the pancreas to secrete more insulin by binding itself to specific receptors on the pancreatic beta cells. This increased secretion helps lower blood glucose levels.
Metformin (500 mg): Metformin is a biguanide that works by reducing the amount of glucose produced by the liver and enhancing insulin sensitivity in body tissues. The sustained-release form of this component ensures a steady release of the medicine, providing constant control over blood sugar levels throughout the day.
Voglibose (0.2 mg): Voglibose is an alpha-glucosidase inhibitor that works by delaying the breakdown of complex carbohydrates into simple sugars in your intestines. This delay reduces post-meal blood sugar spikes, helping maintain balanced glucose levels in your body.
If you're pregnant, be careful taking Glyciphage-VG2 Tablet. It's best to have a chat with your doctor before starting this medicine.
For lactating mothers, Glyciphage-VG2 Tablet is not recommended. Make sure to have a conversation with your doctor to understand the potential risks and benefits.
Alcohol consumption should be limited or avoided while on Glyciphage-VG2 Tablet as it can enhance metformin's effect on lactate metabolism and increase the risk of hypoglycaemia with glimepiride.
Use Glyciphage-VG2 Tablet with caution if you have mild to moderate liver problems. This medicine is not recommended for severe liver diseases. Discuss any liver issues with your doctor before beginning treatment as it may affect liver function.
If you've had kidney problems in the past, take care when using this medicine. Metformin, one of the ingredients, is contraindicated in severe renal impairment, hence consulting your doctor beforehand is advised.
Glyciphage-VG2 Tablet does not usually impact your ability to drive or operate machinery. However, hypoglycaemia (low blood sugar) can cause dizziness and confusion which might affect these activities.
If you are allergic to metformin, glimepiride, or voglibose - the active ingredients in Glyciphage-VG2 Tablet - or any other excipients mentioned on the product label, avoid taking this medicine.
Glyciphage-VG2 Tablet is meant for adults and not for children under 18 years of age. Always consult a doctor before giving any medication to a child.
Older patients should use Glyciphage-VG2 Tablet under medical supervision. They may be more susceptible to its side effects, and they might also have liver and kidney issues. Your doctor will guide you based on your health status.
Glyciphage-VG2 Tablet interacts with the following medicines:
Antihypertensives such as captopril, and enalapril: The concomitant use of this tablet with antihypertensives can increase insulin sensitivity and potentiate blood glucose-lowering effects and may cause hypoglycaemia.
Antianginal agents such as ranolazine: It may increase the blood concentration of this tablet.
An anticonvulsant agent such as phenytoin: It may lead to hyperglycemia and may lead to loss of glycemic control.
Glyciphage-VG2 Tablet has no known specific food interactions. However, it is generally advised to maintain a balanced diet while on any medication for diabetes management.
Glyciphage-VG2 Tablet interacts with the following diseases:
Diabetic Ketoacidosis: This medicine is not suitable for use in patients with diabetic ketoacidosis.
Heart Failure: Patients with heart failure should use this medication cautiously.
G6PD Deficiency: Use cautiously as sulfonylureas like glimepiride in Glyciphage-VG2 Tablet can cause haemolytic anaemia in these patients.
Your doctor will prescribe the correct dose of Glyciphage-VG2 Tablet for you. This can depend on factors like your response to the medicine and the severity of your condition. It's vital to stick to this prescribed dosage and not exceed it without consulting your doctor.
In case you accidentally take more Glyciphage-VG2 Tablets than recommended, you might experience hypoglycemia or low blood sugar. To combat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins). Seek medical attention if hypoglycemia persists.
If you forget to take a dose of Glyciphage-VG2 Tablet, take it as soon as you remember. But if it's nearly time for the next dose, skip the missed one and continue with your usual schedule. Do not increase your dosage without discussing with your doctor.
Always store your Glyciphage-VG2 Tablet in a cool and dry place.
The ideal temperature is room temperature, around 20-25°C.
Keep the product shielded from light to maintain its effectiveness.
Ensure the medicine is kept out of reach from children for their safety.
Remember to use this medicine before its expiry date for best results.
Make sure to have balanced meals. Glyciphage-VG2 Tablet works best when you follow a diet low in simple sugars. This aids the medication in controlling your blood sugar levels.
Regular exercise can also help manage type 2 diabetes. Try to engage in moderate physical activity regularly, as it can enhance insulin sensitivity and help lower blood glucose levels. Please consult your doctor before starting any new exercise regimen.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Type 2 Diabetes |
| Drug Category | Sulfonylurea, Biguanide, Alpha-glucosidase Inhibitor |
| Therapeutic Category | Antidiabetic |
Glyciphage-VG2 Tablet helps manage blood sugar levels in adults with type 2 diabetes who need a combination of three medicines.
It lowers blood sugar by increasing insulin release, decreasing glucose production in the liver, and slowing down carbohydrate breakdown in the intestines.
No, you should swallow the whole tablet with water. Chewing or crushing it can affect how well it works.
Take it as soon as you remember, with food. If it's nearly time for your next dose, skip the missed one.
Common side effects include low blood sugar, nausea, diarrhoea, abdominal discomfort, and weight gain.
Yes, avoid excessive alcohol and inform your doctor if you have fever, infection, injury or plan any surgery.
Yes, some medicines can interfere with its action. Always inform your doctor about all medications and supplements you're taking.
Check out Editorial Policy
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
Glimepiride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00222
Voglibose: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB04878
Amaryl. (n.d.). Metformin hydrochloride (SR), glimepiride, & voglibose tablets [Pharmaceutical]. https://www.sanofi.in/dam/jcr:99ce79b7-f940-4c0e-ae78-225fbf7b45b3/Amaryl%20MV%20PI.pdf
Bantwal, G., Ayyar, V., Kovil, R., Chawla, M., Shah, T., Kumar, S., Abhyankar, M., & Revankar, S. (2021). Assessment of clinical experience of triple drug fixed-dose combination of glimepiride, metformin and voglibose in the management of Type 2 diabetes mellitus: a retrospective study. Journal of Clinical and Diagnostic Research. https://doi.org/10.7860/jcdr/2021/47919.15346
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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