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APRIGLIM MV 2 TABLET 15 is used to manage type 2 diabetes. Combining glimepiride, metformin, and voglibose, it stimulates insulin release, reduces liver glucose production, and slows carbohydrate absorption.
Before taking this medicine, consult your doctor for the correct dosage and to ensure it aligns with your medical history. Inform them of any ongoing medications and continue the prescribed treatment for optimal results.
APRIGLIM MV 2 TABLET 15 is used to manage type 2 diabetes mellitus by reducing high blood sugar levels. This combination of glimepiride, metformin, and voglibose works to increase insulin release, reduce glucose production, and slow carbohydrate absorption, helping to maintain better glycaemic control throughout the day.
Swallow the whole tablet with your morning meal.
Ensure that you do not crush, chew, or split the tablet.
If you're transitioning from separate formulations of glimepiride, metformin or voglibose, consult your doctor for guidance.
Always consult your doctor for specific advice on medicine usage.
APRIGLIM MV 2 TABLET 15 is taken orally.
APRIGLIM MV 2 TABLET 15 may cause upper respiratory tract infection, diarrhoea, nausea, vomiting, abdominal discomfort, indigestion, and low blood sugar (hypoglycaemia). If these side effects worsen or do not improve, seek medical attention.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of APRIGLIM MV 2 TABLET 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Diarrhoea: Consider taking APRIGLIM MV 2 TABLET 15 with food to potentially lessen this effect.
Nausea or vomiting: If you feel unwell after taking this medicine, you might find it helpful to take it after meals instead.
APRIGLIM MV 2 TABLET 15 is composed of three active components:
Metformin hydrochloride (500 mg): This component works by reducing glucose production in your liver, decreasing absorption of glucose from your intestines, and improving insulin sensitivity, which enhances peripheral glucose uptake and use.
Glimepiride (2 mg): This component works by stimulating insulin secretion from certain cells in your pancreas called beta cells. It also has additional effects that increase insulin sensitivity in the peripheral tissues of your body.
Voglibose (0.2 mg): This component acts by temporarily inhibiting certain enzymes in your intestines that break down complex sugars into glucose. By doing so, it slows down glucose absorption and helps control spikes in blood sugar levels after meals.
APRIGLIM MV 2 TABLET 15 is not recommended if you are pregnant. It's best to discuss this with your doctor before starting this medication.
The components of APRIGLIM MV 2 TABLET 15 can pass into breast milk. If you are breastfeeding, consult your doctor to understand the potential risks and benefits before taking this medicine.
Alcohol may intensify the effect of this medicine on blood sugar levels and increase the risk of lactic acidosis. Avoid excessive alcohol intake while taking APRIGLIM MV 2 TABLET 15.
If you have liver problems, it's advisable to discuss them with your doctor before starting APRIGLIM MV 2 TABLET 15. This medicine may affect your liver function.
APRIGLIM MV 2 TABLET 15 is not recommended if you have severe kidney impairment. If you have a history of kidney problems, ensure you consult your doctor before taking this medicine.
This medicine might cause dizziness or fatigue which could affect the ability to drive or operate machinery. If you experience these symptoms, avoid driving or using heavy machinery.
If you've had an allergic reaction to glimepiride, metformin, voglibose or any other ingredients in APRIGLIM MV 2 TABLET 15, it's important to inform your doctor before starting this medication.
APRIGLIM MV 2 TABLET 15 is designed for adult use; it is not recommended for children under 18 years of age. Always consult a doctor before giving any medication to a child.
Older patients should take APRIGLIM MV 2 TABLET 15 under medical supervision as they may be more susceptible to its side effects and might also have liver and kidney issues. Your doctor will guide you based on your health status.
APRIGLIM MV 2 TABLET 15 interacts with the following medicines:
Cationic medicines: Certain medicines like amiloride, digoxin, morphine, and ranitidine can potentially interfere with metformin, an active component in APRIGLIM MV 2 TABLET 15, as they compete for the same renal tubular transport systems. This may alter the effectiveness of APRIGLIM MV 2 TABLET 15.
Hyperglycaemia-inducing medicines: Certain medications, such as estrogens, phenytoin, and isoniazid, may cause high blood sugar levels and may affect the glucose-controlling effect of APRIGLIM MV 2 TABLET 15.
High-fat meals: Consuming high-fat meals while on APRIGLIM MV 2 TABLET 15 could alter its absorption and effectiveness.
APRIGLIM MV 2 TABLET 15 interacts with the following diseases:
Renal impairment: Patients suffering from kidney disease should not take APRIGLIM MV 2 TABLET 15 as it could worsen their condition.
Metabolic acidosis: Patients with metabolic disorders, including diabetic ketoacidosis, should avoid this medicine due to potential health risks.
The daily dose of APRIGLIM MV 2 TABLET 15 should be as advised by your doctor. This can vary depending on the severity of your condition and how you respond to the medicine. It's crucial to follow the prescribed dosage and not to exceed it without consulting your doctor. For further details regarding dosage, please read the package insert.
If you accidentally take more than the recommended dose of APRIGLIM MV 2 TABLET 15, you may experience symptoms such as nausea, diarrhoea, and stomach discomfort. If these symptoms persist or worsen, inform your doctor.
If you forget to take your regular dose of APRIGLIM MV 2 TABLET 15, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue with your regular schedule. Never double up on doses without consulting your doctor.
Store APRIGLIM MV 2 TABLET 15 at a temperature below 30°C.
Keep it protected from light and moisture.
Maintain the medicine in its original packaging until it's time to take it.
Always keep this medication out of reach of children.
Follow a balanced diet low in simple sugars: As APRIGLIM MV 2 TABLET 15 is used to manage type 2 diabetes, reducing your intake of foods high in simple sugars can help control blood glucose levels.
Regular physical activity: Engage in moderate exercise like brisk walking or cycling daily. Exercise can help improve your body's insulin sensitivity, supporting better blood glucose control.
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Type 2 Diabetes Mellitus |
| Drug Category | Sulfonylurea, Biguanide, Alpha-glucosidase Inhibitor |
| Therapeutic Category | Antidiabetic |
APRIGLIM MV 2 TABLET 15 is used to manage type 2 diabetes mellitus in adults, along with a proper diet and exercise routine.
This medicine combines three active ingredients that work together to control blood sugar levels by increasing insulin release, reducing glucose production, and slowing down carbohydrate absorption.
You should take Trimetaday V-2 with your morning meal as prescribed by your doctor. Always swallow the whole tablet; do not crush or chew it.
It's not recommended to use this medicine during pregnancy or while breastfeeding. Inform your doctor if you are pregnant or breastfeeding, if this medicine is prescribed to you.
Excessive alcohol intake can increase the risk of lactic acidosis while on this medicine. It's better to avoid drinking alcohol excessively when taking it.
Overdose can lead to severe hypoglycaemia, which is a medical emergency requiring immediate hospitalisation. If suspected, seek medical help right away.
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Sista, S., & Jain, L. (2013). CLINICAL PHARMACOLOGY AND BIOPHARMACEUTICS REVIEW(S). In CENTRE FOR DRUG EVALUATION AND RESEARCH, CENTRE FOR DRUG EVALUATION AND RESEARCH. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2014/205649Orig1s000ClinPharmR.pdf
Unknown. (n.d.-b). GLUMETZA: Metformin Hydrochloride Extended Release Tablets Description, Clinical Pharmacology, Pharmacokinetics, Special Populations. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf
Comparison of acarbose and voglibose in diabetes patients who are inadequately controlled with basal insulin treatment: Randomised, parallel, Open-Label, Active-Controlled study. (n.d.). NIH NLM. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890482/
Website, N. (2022a, March 17). How and when to take glimepiride. nhs.uk. https://www.nhs.uk/medicines/glimepiride/how-and-when-to-take-glimepiride/
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.-b). DrugBank. https://go.drugbank.com/drugs/DB00331
Glimepiride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.-b). DrugBank. https://go.drugbank.com/drugs/DB00222
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 444020, Voglibose. Retrieved June 9, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Voglibose.
National Center for Biotechnology Information (2024). PubChem Compound Summary for, Glimepiride. Retrieved June 9, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Glimepiride.
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 14219, Metformin Hydrochloride. Retrieved June 9, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Metformin-Hydrochloride.
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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