Rapilif D 4/0.5 Tablet 10

Q: What is Rapilif D 4/0.5 Tablet 10 used for?

Rapilif D 4/0.5 Tablet 10 is used to treat benign prostatic hyperplasia (BPH), a condition in men characterized by an enlarged prostate that can cause urinary difficulties.

Q: How does Rapilif D 4/0.5 Tablet 10 work?

It works by inhibiting the enzyme that converts testosterone into dihydrotestosterone (DHT), a hormone that causes prostate growth, thereby reducing the size of the prostate and relieving symptoms.

Q: How should I take Rapilif D 4/0.5 Tablet 10?

Take Rapilif D 4/0.5 Tablet 10 exactly as prescribed by your doctor, usually with or without food. Swallow the tablet whole without chewing or breaking it.

Q: Can anyone use Rapilif D 4/0.5 Tablet 10?

No, it is intended only for adult men with BPH. Women, children, and those with liver impairment should avoid using this medicine.

Q: Can Rapilif D 4/0.5 Tablet 10 interact with other medicines?

Yes, this tablet may interact with certain medications, particularly blood pressure-lowering medicines like verapamil and diltiazem and medicines metabolised by the liver. Consult your doctor about potential interactions.

Q: What are the common side effects of Rapilif D 4/0.5 Tablet 10?

Common side effects include headache, stuffy nose or runny nose, diarrhoea, and dizziness. If side effects persist or worsen, contact your doctor.

Q: How should I store my Rapilif D 4/0.5 Tablet 10?

Store Rapilif D 4/0.5 Tablet 10 in a cool, dry place away from direct sunlight, and keep them out of reach of children.

Ipca Laboratories Pvt Ltd.

Strip of 10 Units

Read Info

MRP ~~₹276.09~~

₹231.92

₹27.61/Units

16% off

*MRP inclusive of all taxes

100% genuine medicines

Safe & secure payments

15 days Easy returns

Prescription required for this medicine

Store Below 30° C

Composition

Dutasteride (0.5 Mg) + Silodosin (4 Mg)

Rapilif D 4/0.5 Tablet 10 is used to manage the signs and symptoms of Benign prostatic hyperplasia (BPH) or enlarged prostate. It is a combination medicine and belongs to the category of selective alpha-1 adrenergic receptor antagonists.

It helps manage lower urinary tract symptoms, such as dribbling and urinary retention, thereby enhancing the quality of life for patients with BPH. While it doesn’t cure the condition, it provides effective symptom relief.

Be sure to inform your doctor about any existing health conditions, allergies, and other medications you are taking. Your doctor will determine the appropriate dosage and frequency. If you experience any persistent or worsening side effects, seek medical advice.

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Rapilif D 4/0.5 Tablet 10 is used in the management of:

Benign Prostatic Hyperplasia: It provides symptomatic relief in such patients by relieving lower urinary tract symptoms such as difficulty in urination, dribbling of urine, weak stream of urine, and incomplete emptying of the bladder.

Take Rapilif D 4/0.5 Tablet 10 with a glass of water.
Swallow the tablet as a whole; do not crush or chew it.
This medication should be taken preferably with meals.
This tablet is recommended to be taken at a fixed daily time.

Rapilif D 4/0.5 Tablet 10 should be taken orally.

The side effects of Rapilif D 4/0.5 Tablet 10 include:

Diarrhoea
Dizziness
Orthostatic Hypotension/Postural Hypotension (Low blood pressure associated with posture which occurs when the patient stands after sitting or lying for a while)
Stuffy nose or runny nose
Headache
Nasopharyngitis (Inflammation of the Nose and Pharynx)

Management Of Side Effects:

Most of the side effects are temporary and harmless, and get resolved by discontinuing the tablet. These may not require medical attention. To combat gastrointestinal side effects, take this tablet with food. If you experience any severe or persistent side effects due to this tablet, consult your doctor.

Rapilif D 4/0.5 Tablet 10 contains the following components:

Silodosin (4 mg): It is an alpha-adrenergic antagonist that works by blocking the alpha 1A type of adrenoceptors located in the prostate gland, urethra and urinary bladder. It leads to the relaxation of smooth muscles in these locations, thus, easing urinary flow.
Dutasteride (0.5 mg): It is 5-alpha reductase inhibitor that works by inhibition of both type 1 and 2 of 5-alpha reductase. It is responsible for the conversion of testosterone to 5-alpha dihydrotestosterone. It is responsible for the initial development and subsequent enlargement of the prostate gland.

Pregnancy

Not applicable

Breastfeeding

Not applicable

Alcohol

Avoid alcohol consumption while on Rapilif D 4/0.5 Tablet 10 as it can aggravate the orthostatic hypotension caused by this medicine.

Liver

Rapilif D 4/0.5 Tablet 10 should not be given to patients with severe liver disease or impairment. Dose adjustment is needed for mild to moderate liver disease after consultation with a doctor.

Kidney

Rapilif D 4/0.5 Tablet 10 should not be given to patients with severe kidney disease or impairment. Dose adjustment is needed for mild to moderate kidney disease after consultation with a doctor.

Use In Driving And Operating Machinery

Rapilif D 4/0.5 Tablet 10 can cause postural hypotension and dizziness which can impair driving and machine operating capability. Refrain from such activities while you are taking this medication.

Allergy

If you are allergic to Rapilif D 4/0.5 Tablet 10 or any of its constituents, do not take it.

Children

Rapilif D 4/0.5 Tablet 10 are not indicated for use in paediatric patients (<18 years of age).

Older Patients

Rapilif D 4/0.5 Tablet 10 is to be used with caution in elderly patients with liver or kidney disease, as they usually need dose adjustment after consultation with a doctor.

Drug-Drug Interactions

Rapilif D 4/0.5 Tablet 10 interact with the following medicines:

Antifungals like itraconazole and ketoconazole should not be taken with this medicine as it may increase the effect of this tablet.
Blood pressure-lowering medicines like verapamil and diltiazem can aggravate Orthostatic Hypotension caused by this tablet.
Antivirals like ritonavir decrease the metabolism of this medicine and increase its effects and side effects.
Immune-suppressing medications like cyclosporine should not be given with this tablet, as it might increase the effect of this medicine.
Antibiotics like clarithromycin and erythromycin should not be used with this tablet, as they can reduce the effectiveness of this medicine.
Erectile dysfunction medicines like tadalafil and sildenafil (PDE-5 inhibitors) increase the side effects of this tablet, like orthostatic hypotension, dizziness, etc.

Drug-Food Interactions

High-fat or Moderate-calorie meals: Rapilif D 4/0.5 Tablet 10 interacts with high-fat or moderate-calorie meals as its consumption can reduce the plasma concentration of Rapilif D 4/0.5 Tablet 10 and thus reduce its effect.

Drug-Disease Interactions

Rapilif D 4/0.5 Tablet 10 interact with the following diseases:

Severe kidney diseases: It can aggravate the disease.
Severe liver diseases: The tablet can worsen the disease.

Daily Dose

The daily dose of Rapilif D 4/0.5 Tablet 10 should be taken as prescribed by your doctor. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is important to follow the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

If you or someone else takes an excessive amount of Rapilif D 4/0.5 Tablet 10 by accident, inform your doctor immediately and follow his advice. The overdose symptoms of Rapilif D 4/0.5 Tablet 10 include dizziness, fainting, lightheadedness and blurred vision. Be vigilant and do not ignore these symptoms.

Missed Dose

If you forget to take Rapilif D 4/0.5 Tablet 10, take it as soon as you remember. If the time for the next dosage is close, skipping the missed one and resuming your regular dosage pattern is recommended.

Store Rapilif D 4/0.5 Tablet 10 at room temperature (15-25ºC).
Protect Rapilif D 4/0.5 Tablet 10 from light and moisture.
Keep it away from children and pets
Do not use this medicine after the expiry date has passed.

Reduce the intake of substances that increase diuresis, like coffee and alcohol.
Perform regular pelvic exercises for symptomatic relief.
In case of anticipated eye surgery for cataracts or glaucoma, inform the doctor about your consumption of this medicine.
Get your PSA (Prostate-specific antigen) levels checked regularly to rule out the development of cancer in the Prostate gland as well as to document improvement in Benign Prostatic Hyperplasia.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Symptomatic relief from lower urinary tract symptoms in Benign prostatic hyperplasia
Drug Category	Selective alpha-1 adrenergic receptor antagonist
Therapeutic Category	Urology

What is Rapilif D 4/0.5 Tablet 10 used for?

Rapilif D 4/0.5 Tablet 10 is used to treat benign prostatic hyperplasia (BPH), a condition in men characterized by an enlarged prostate that can cause urinary difficulties.

How does Rapilif D 4/0.5 Tablet 10 work?

It works by inhibiting the enzyme that converts testosterone into dihydrotestosterone (DHT), a hormone that causes prostate growth, thereby reducing the size of the prostate and relieving symptoms.

How should I take Rapilif D 4/0.5 Tablet 10?

Take Rapilif D 4/0.5 Tablet 10 exactly as prescribed by your doctor, usually with or without food. Swallow the tablet whole without chewing or breaking it.

Can anyone use Rapilif D 4/0.5 Tablet 10?

No, it is intended only for adult men with BPH. Women, children, and those with liver impairment should avoid using this medicine.

Can Rapilif D 4/0.5 Tablet 10 interact with other medicines?

Yes, this tablet may interact with certain medications, particularly blood pressure-lowering medicines like verapamil and diltiazem and medicines metabolised by the liver. Consult your doctor about potential interactions.

What are the common side effects of Rapilif D 4/0.5 Tablet 10?

Common side effects include headache, stuffy nose or runny nose, diarrhoea, and dizziness. If side effects persist or worsen, contact your doctor.

How should I store my Rapilif D 4/0.5 Tablet 10?

Store Rapilif D 4/0.5 Tablet 10 in a cool, dry place away from direct sunlight, and keep them out of reach of children.

Last Updated On 05 Jun. 2025 | 12:38PM (IST)

Certified Content

Written by

Dr. Nikhil Ambatkar

Medical Content Reviewer | 8 years

PhD (Biotechnology)

Reviewed by

Dr. Betina Chandolia

Lead Medical Content Reviewer | 11 years

BDS, MDS, PGCCL, PGDMH

Check out Editorial Policy

Manufacturer details

125, Charkop Rd, Kandivali, Charkop, Charkop Industrial Estate, Kandivali West, Mumbai, Maharashtra 400067

Country of origin: INDIA

Expiry on or after: October 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

RAPAFLO ® (silodosin) tablet for oral use. (n.d.). Fda.Gov.(Retrieved December 2023). https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022206s012lbl.pdf
Silodosin. (n.d.). Medlineplus.Gov. (Retrieved December 2023). https://medlineplus.gov/druginfo/meds/a609002.html
Dutasteride. (n.d.). Medlineplus.Gov. (Retrieved December 2023). https://medlineplus.gov/druginfo/meds/a603001.html
Westfall, T.C., MacArthur, H., Westfall, D.P. (2018). Adrenergic Agonists and Antagonists. In Goodman & Gilman’s: The Pharmacological Basis of Therapeutics (13th ed., pp. 209, 221t, 523t). essay, McGraw Hill Medical.
Urorec. (n.d.). Europa.Eu.(Retrieved December 2023). https://www.ema.europa.eu/en/medicines/human/EPAR/urorec
DailyMed - RAPAFLO- silodosin tablet. (n.d.). Nih.Gov. (Retrieved December 2023). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=96425d91-cfe1-477d-a130-b58c330ca8a3
Dutasteride. (n.d.). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB01126

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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