Perinorm Cd Capsule 10

Ipca Laboratories Pvt Ltd.

Strip of 10 UNITS

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MRP ~~₹122.85~~

₹98.28

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Composition

Metoclopramide (15 Mg)

Perinorm-CD Capsule is primarily used for managing the symptoms of gastroparesis in adults. This medicine belongs to a group of medications known as prokinetic agents.

In addition to this main use, it also offers relief from other conditions that are associated with slowed movement in the gastrointestinal tract. These may include feelings of fullness after eating a small amount of food, bloating, and stomach pain.

Before you start taking this medicine, it's important to consult your doctor who will guide you on the right dosage and frequency. Inform your doctor about any pre-existing conditions or ongoing medications you are taking. If you notice any side effects while on this medicine, notify your doctor right away. Continue taking the capsule for the duration prescribed by your doctor for optimal results.

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Providing symptomatic relief in acute diabetic gastroparesis: This condition is common in adults with diabetes and leads to symptoms like early satiety, nausea, and vomiting.
Managing recurrent diabetic gastroparesis: This medicine helps manage recurring episodes of delayed gastric emptying in adults suffering from diabetes.

Swallow the capsule whole with a glass of water.
The capsule should not be crushed or chewed to maintain its controlled-release properties.
It is generally advised to take this medicine 30 minutes before meals and at bedtime.
Always consult your doctor for specific advice on how to use this medicine.

Perinorm-CD Capsule is taken orally.

Drowsiness
Fatigue
Restlessness and irritability
Extrapyramidal symptoms: These are unusual body movements or postures, such as tremors or slowed movements.
Galactorrhoea: This is an unusual condition where a person who is not breastfeeding produces milk.
Increased urinary frequency: You may find yourself needing to urinate more often than usual.

Managing the Side Effects:

Drowsiness: If Perinorm-CD Capsule makes you drowsy, consider taking it before you go to bed.
Restlessness and irritability: Taking this medicine after meals might help to decrease feelings of restlessness and irritability.

Perinorm-CD Capsule contains metoclopramide (15 mg), which works on your body as follows:

Dopamine D2 Receptor Inhibition: Metoclopramide blocks dopamine D2 receptors that are found both in your brain and your gut. Blocking these receptors helps stimulate the muscles in your gastrointestinal tract.
Serotonin 5-HT4 Receptor Stimulation: It also stimulates serotonin 5-HT4 receptors present in your gut. This further aids the movement of food through your digestive tract.
Muscarinic Receptor Enhancement: Metoclopramide enhances the activity at muscarinic receptors which contributes to its prokinetic effects.

Pregnancy

If you are pregnant, caution is recommended while taking Perinorm-CD Capsule. It is best to consult your doctor before taking this medicine.

Breastfeeding

While breastfeeding, it is advised to be careful with Perinorm-CD Capsule as it is excreted in breast milk. Make sure to consult your doctor in order to understand potential risks and benefits.

Alcohol

The combination of Perinorm-CD Capsule and alcohol may result in additive sedative effects. It's wise to limit your alcohol intake or avoid it altogether while on this medication.

Liver

Perinorm-CD Capsule may need careful administration if you have liver problems, especially cirrhosis, as the clearance of the medicine can be affected. Ensure you discuss any liver-related health concerns with your doctor before starting this medicine.

Kidney

The functioning of your kidneys can influence how Perinorm-CD Capsule works in your body. If you have kidney issues, please consult your doctor before taking this medicine.

Using Machines & Driving

Due to possible side effects like drowsiness or fatigue, Perinorm-CD Capsule might affect your ability to drive or operate machinery. Be cautious and ensure you know how it affects you before engaging in such activities.

Allergy

Perinorm-CD Capsule is contraindicated if you have known hypersensitivity to metoclopramide or any other components of the capsule. Consult with your doctor if you have a history of allergic reactions.

Children

Perinorm-CD Capsule is intended for adult use and caution is advised while giving this medicine to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Perinorm-CD Capsule under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Cytochrome P450 2D6 (CYP2D6) Inhibitors: Medicines like quinidine can increase metoclopramide levels and toxicity due to their inhibitory effect on CYP2D6, the enzyme that metabolises metoclopramide.
Sedatives and Hypnotics: The sedative effects of medicines like diazepam and lorazepam can be enhanced when taken with Perinorm-CD Capsule due to its potential CNS depressant action.
Anticholinergic Medications: Medicines like atropine may counteract the prokinetic effects of Perinorm-CD Capsule by inhibiting the actions of acetylcholine, a neurotransmitter that promotes gastrointestinal motility.
Monoamine Oxidase Inhibitors (MAOIs): These medicines, such as phenelzine, can potentiate the extrapyramidal side effects of Perinorm-CD Capsule.

Drug-Food Interactions

There are no specific food items identified that interact with Perinorm-CD Capsule. However, it's always wise to take your medicine as directed by your doctor.

Drug-Disease Interactions

Liver Disease: Metoclopramide is metabolised in the liver; liver disease could impair this process and increase medication levels, potentially leading to an increased risk of side effects.
Kidney Disease: Kidney disease may affect how metoclopramide is removed from your body, possibly requiring dosage adjustments.
Diabetes: Perinorm-CD Capsule may alter insulin requirements in diabetic patients due to its gastrointestinal motility-enhancing action.

Daily Dose

Your daily dosage of Perinorm-CD Capsule depends on your doctor's prescription. It can vary based on factors like severity of the condition and how you respond to the medicine. Always adhere to the prescribed dosage and don't exceed it without a consultation with your doctor.

Over Dose

Accidental overdose of Perinorm-CD Capsule may result in side effects like drowsiness, restlessness, or confusion. If you notice any such symptoms persisting or worsening, inform your doctor. However, always remember to take the correct dosage as prescribed by your doctor.

Missed Dose

If you forget to take your regular dose of Perinorm-CD Capsule, take it as soon as you remember. If it's nearly time for the next dose, skip the missed one and continue with your usual dosage schedule. Never adjust your dosage without consulting your doctor.

Store Perinorm-CD Capsule in a dry place away from light and moisture.
The optimal storage temperature is between 20°C to 25°C.
Keep the medicine in its original packaging until it's time to take it.
Ensure the medicine is always kept out of the reach and sight of children.
Always use this medicine before the expiry date on the pack.

If you have diabetes, it's crucial to maintain a balanced diet with regular meals, limiting high-sugar foods. This can help manage your blood sugar levels, which could alleviate symptoms related to diabetic gastroparesis.
Regular exercise can also be beneficial. It can improve your overall health and may potentially aid in managing the symptoms of gastroparesis by promoting better digestion. Do consult your doctor regarding suitable physical activities for your condition.

Fact Box

Drug Category	Dopamine Antagonist
Therapeutic Category	Gastroprokinetic Agent
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Gastroparesis, Nausea

What is Perinorm-CD Capsule used for?

This medicine is used to manage symptoms of diabetic gastroparesis, a condition where the stomach empties too slowly, causing nausea, vomiting and abdominal pain.

How does Perinorm-CD Capsule work?

It contains metoclopramide, which promotes movement in the stomach and intestines. It also helps control nausea and vomiting by acting on certain brain receptors.

Can I crush or chew Perinorm-CD Capsule?

No, you should swallow the capsule whole. Crushing or chewing it may disrupt its controlled-release properties, reducing its effectiveness.

Are there any side effects of Perinorm-CD Capsule?

Yes, common side effects include drowsiness, restlessness, and sometimes movement disorders. Rarely, it can cause depression or confusion. Always consult your doctor if side effects persist.

What precautions should I take while using Perinorm-CD Capsule?

Avoid this medicine if you have certain conditions like gastrointestinal obstruction or epilepsy. Be cautious if you have a history of depression or Parkinson's disease.

Can I use other medicines while taking Perinorm-CD Capsule?

Some medicines can interact with metoclopramide, affecting its action or causing unwanted side effects. Discuss all your current medications with your doctor before starting this medicine.

How should I store my Perinorm-CD Capsules?

Store them at room temperature (20°C to 25°C), protected from light and moisture. Keep them in their original packaging until it's time for a dose.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

125, Charkop Rd, Kandivali, Charkop, Charkop Industrial Estate, Kandivali West, Mumbai, Maharashtra 400067

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

HIGHLIGHTS OF PRESCRIBING INFORMATION. (1979). [Prescribing information]. In REGLAN TABLETS. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/017854s062lbl.pdf
Isola, S., Hussain, A., Dua, A., Singh, K., & Adams, N. (2023, September 4). Metoclopramide. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK519517/
Metoclopramide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01233
Metoclopramide: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a684035.html
PubChem. (n.d.). Metoclopramide. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Metoclopramide

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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