Metoclopramide

Dosage Forms Available

• Metoclopramide can be taken orally (tablets, orally disintegrating tablets (ODT), syrup or solution) and intramuscular (IM) or intravenous (IV) infusion.

Age and Dose Restrictions

• This medicine is typically prescribed to adults.

Contraindications

• Metoclopramide is contraindicated in patients with known hypersensitivity to Metoclopramide.
• It is also contraindicated in patients with gastrointestinal bleeding, obstruction, or perforation, epilepsy or Parkinson's disease, and pheochromocytoma (a rare adrenal gland tumour).

Other Medications to Avoid

• This medication may interact with anti-psychotics (eg., chlorpromazine), Monoamine Oxidase Inhibitors (eg., phenelzine or tranylcypromine), and opioid analgesics (eg., morphine and codeine)

Overdose and Missed Dose

• An overdose of Metoclopramide can lead to agitation, restlessness and possibly extrapyramidal symptoms. If you suspect an overdose, consult your doctor immediately.
• If you miss a dose and it's not yet time for your next dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and continue with your regular schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage side effects like dry mouth or constipation.

Use in Driving and Operating Machinery

• Metoclopramide can interact with your ability to drive or operate heavy machines. Do not drive or operate machines if you feel drowsiness or dizziness after taking this medication.

Use in Pregnancy and Lactation

• Metoclopramide crosses the placenta and is found in breast milk. Therefore, it should be used with caution during pregnancy and breastfeeding. Always consult your doctor before using this medicine during these times.

Caution in Other Conditions

• Patients with liver or kidney disease should exercise caution while taking Metoclopramide.
• Patients diagnosed with diabetes mellitus need to be careful, as Metoclopramide can affect blood sugar levels.
• Special care should be taken if you have a history of depression, as this medicine can worsen your symptoms.

Special Dietary and Lifestyle Recommendations

• Avoid lying down immediately after meals to prevent acid reflux.
• Limit caffeine intake as it can increase stomach acidity and worsen conditions like GERD.