Glura M Xr 500 Tablet 15

Q: What is Glura M Xr 500 Tablet 15 used for?

Glura M Xr 500 Tablet 15 is used to manage blood sugar levels in adults with type 2 diabetes in conjunction with diet, exercise, and weight control.

Q: How do the ingredients in Glura M Xr 500 Tablet 15 work?

Metformin reduces glucose production in the liver, intestinal glucose absorption, and improves insulin sensitivity. Sitagliptin helps increase insulin synthesis and release.

Q: What happens if I miss a Dose of Glura M Xr 500 Tablet 15?

If it's almost time for your next dose, skip the one you missed. Don't double your dose to make up for the missed one.

Q: Can I take Glura M Xr 500 Tablet 15 during pregnancy?

Glura M Xr 500 Tablet 15 is not advised during pregnancy as it may harm the unborn baby. Always consult your doctor before use.

Q: Should I be aware of any side effects of Glura M Xr 500 Tablet 15?

Common side effects may include diarrhoea, upper respiratory tract infection, headache, nausea, vomiting, gas, and weakness. Consult your doctor if they persist or worsen.

Q: Are there any precautions I should take while using Glura M Xr 500 Tablet 15?

Use this medicine with caution if you have heart problems, liver impairment, or vitamin B12 deficiency. Alcohol use should be minimised.

Q: How should I store my Glura M Xr 500 Tablet 15?

Store your tablet at a temperature not exceeding 30°C, away from light, moisture, and children's reach.

Eris Lifesciences Ltd

Strip of 15 Units

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MRP ~~₹214.39~~

₹177.94

₹14.29/Units

17% off

*MRP inclusive of all taxes

100% genuine medicines

Safe & secure payments

15 days Easy returns

Prescription required for this medicine

Store Below 30° C

Composition

Metformin (500 Mg) + Sitagliptin (50 Mg)

Glura M Xr 500 Tablet 15 is used to control high blood sugar levels in adults with type 2 diabetes.

It contains sitagliptin, which helps the pancreas release more insulin when blood sugar is high, and metformin, which helps the body use insulin more effectively and reduces the amount of glucose produced by the liver. This combination helps improve blood sugar control.

Take Sitara M 50/500 Tablet with meals, as prescribed by your doctor, to reduce the chance of stomach upset. Continue with a balanced diet and regular exercise for better long-term control.

Tell your doctor about any history of pancreatitis or kidney problems before starting. Seek medical advice if you have severe stomach pain or persistent vomiting.

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Glura M Xr 500 Tablet 15 is used to manage type 2 diabetes in adults by improving insulin release, reducing glucose production in the liver, and improving insulin sensitivity.

Primary Uses of Glura M Xr 500 Tablet 15 are:

Blood Sugar Control: Helps keep blood sugar within a healthy range, including after meals.
Complication Prevention: Supports better long-term control, helping reduce the risk of kidney damage, nerve problems, and heart disease.

Swallow the tablet whole with a glass of water.
Do not crush, chew, or split the tablet.
Always stick to the dose recommended by your doctor, and do not alter it on your own.

Glura M Xr 500 Tablet 15 is taken orally.

Glura M Xr 500 Tablet 15 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Glura M Xr 500 Tablet 15:

Digestive: Loose motions (diarrhoea), feeling sick (nausea), vomiting, stomach pain, gas, and bloating. Taking the tablet with food can help ease these.
Nervous System: Headache.
Infections: Upper respiratory tract infections and cold-like symptoms (nasopharyngitis).
Other: Low blood sugar (hypoglycaemia), especially if taken with certain other diabetes medicines.

If side effects do not improve or become serious, speak to your doctor right away.

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Glura M Xr 500 Tablet 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Glura M Xr 500 Tablet 15 with food or milk to lessen this effect.
Indigestion: If you have indigestion, take this medicine after meals to lessen this effect.

Glura M Xr 500 Tablet 15 has two active ingredients that work together to manage type 2 diabetes:

Sitagliptin (50 mg): Sitagliptin maintains the levels of incretin hormones (GLP-1 and GIP) in your body. These hormones help stimulate insulin synthesis and release after meals, which aids in controlling post-meal blood sugar spikes.
Metformin (500 mg): This component works by reducing the production of glucose in your liver, decreasing the absorption of glucose in your gut, and improving insulin sensitivity. This combined action results in lower blood sugar levels.

Pregnancy

Caution is advised while taking Glura M Xr 500 Tablet 15 if you are pregnant. It's best to consult your doctor before taking this medicine, as poorly managed blood sugars can harm the foetus.

Breastfeeding

The safety of this medicine during breastfeeding is not fully established. It's recommended to discuss this with your doctor before using Glura M Xr 500 Tablet 15 if you're breastfeeding.

Alcohol

You are advised to limit your alcohol intake while taking Glura M Xr 500 Tablet 15. Alcohol may increase the risk of lactic acidosis, a potential side effect of metformin.

Liver

If you have liver problems or elevated liver enzymes, caution is needed when taking Glura M Xr 500 Tablet 15. Before you start on this medication, discuss your liver health with your doctor.

Kidney

Glura M Xr 500 Tablet 15 is contraindicated in severe renal impairment conditions. If you have a history of kidney problems, it's crucial to consult your doctor before starting this medication.

Use In Driving And Operating Machinery

No specific precautions exist regarding driving or operating heavy machinery while taking Glura M Xr 500 Tablet 15. However, if you feel dizzy or unwell after taking the medicine, avoid these activities.

Allergy

This medicine is contraindicated if you have a known hypersensitivity to metformin or sitagliptin. If you've had allergic reactions to similar medicines in the past, inform your doctor before starting this medication.

Children

Glura M Xr 500 Tablet 15 is meant for adult use and should not be given to children under 18 years of age unless prescribed by a doctor.

Older Patients

Older patients may need close monitoring while taking Glura M Xr 500 Tablet 15 due to potential side effects and co-existing health conditions. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Glura M Xr 500 Tablet 15 interacts with the following medicines:

Carbonic anhydrase inhibitors: Medications such as acetazolamide or methazolamide may interact with Glura M Xr 500 Tablet 15, increasing the risk of lactic acidosis due to metformin.
Insulin and insulin secretagogues: When taken with Glura M Xr 500 Tablet 15, insulin and sulfonylureas like glimepiride or glibenclamide can cause low blood sugar (hypoglycaemia).
Cationic medicines: Medicines like amiloride or quinidine, which are excreted via renal tubular secretion, may interact with Glura M Xr 500 Tablet 15, leading to an accumulation of metformin.
Diuretics: Furosemide may increase plasma levels of metformin when used with Glura M Xr 500 Tablet 15, enhancing its blood glucose-lowering effect.
Calcium channel blockers: Nifedipine may interact with Glura M Xr 500 Tablet 15, leading to increased absorption and peak concentration (Cmax) of metformin.

Drug-Food Interactions

None

Drug-Disease Interactions

Glura M Xr 500 Tablet 15 interacts with the following diseases:

Renal impairment: Patients with severe renal impairment (eGFR < 30 mL/min/1.73 m²) should avoid Glura M Xr 500 Tablet 15 due to the risk of medicine accumulation and potential toxicity.
Liver disease: Patients with liver disease should use Glura M Xr 500 Tablet 15 cautiously, as it may impact the metabolism of the medication.
Congestive heart failure: Those with heart failure requiring medication should exercise caution when taking Glura M Xr 500 Tablet 15, as it may worsen their condition.
Vitamin B12 deficiency: The metformin component in Glura M Xr 500 Tablet 15 can reduce Vitamin B12 levels; therefore, individuals with a deficiency should be monitored closely.
Hypoxic states: Conditions like cardiovascular collapse (shock) can increase the risk of lactic acidosis, necessitating careful monitoring when using Glura M Xr 500 Tablet 15.

Daily Dose

You should take Glura M Xr 500 Tablet 15 as instructed by your doctor. The dosage can vary based on your individual health condition and response to the medication.

Over Dose

If you accidentally take more Glura M Xr 500 Tablet 15 than prescribed, you may experience symptoms like nausea, weakness, or diarrhoea. If these symptoms occur, kindly consult your doctor.

Missed Dose

If you miss a dose of Glura M Xr 500 Tablet 15, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one.

Store Glura M Xr 500 Tablet 15 at a temperature not exceeding 30°C.
Protect from light and moisture.
Keep out of reach of children.

Incorporating at least 30 minutes of regular physical activity into your daily routine is essential for managing blood sugar levels effectively.
Adopting a balanced diet that is low in sugar and high in fibre is crucial for controlling blood sugar spikes and enhancing the effectiveness of Glura M Xr 500 Tablet 15.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes
Drug Category	Glucose Regulator
Therapeutic Category	Antidiabetic

What is Glura M Xr 500 Tablet 15 used for?

Glura M Xr 500 Tablet 15 is used to manage blood sugar levels in adults with type 2 diabetes in conjunction with diet, exercise, and weight control.

How do the ingredients in Glura M Xr 500 Tablet 15 work?

Metformin reduces glucose production in the liver, intestinal glucose absorption, and improves insulin sensitivity. Sitagliptin helps increase insulin synthesis and release.

What happens if I miss a Dose of Glura M Xr 500 Tablet 15?

If it's almost time for your next dose, skip the one you missed. Don't double your dose to make up for the missed one.

Can I take Glura M Xr 500 Tablet 15 during pregnancy?

Glura M Xr 500 Tablet 15 is not advised during pregnancy as it may harm the unborn baby. Always consult your doctor before use.

Should I be aware of any side effects of Glura M Xr 500 Tablet 15?

Common side effects may include diarrhoea, upper respiratory tract infection, headache, nausea, vomiting, gas, and weakness. Consult your doctor if they persist or worsen.

Are there any precautions I should take while using Glura M Xr 500 Tablet 15?

Use this medicine with caution if you have heart problems, liver impairment, or vitamin B12 deficiency. Alcohol use should be minimised.

How should I store my Glura M Xr 500 Tablet 15?

Store your tablet at a temperature not exceeding 30°C, away from light, moisture, and children's reach.

Last Updated On 30 Jul. 2026 | 12:00PM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 10 years

Doctor of Medicine

Reviewed by

Dr. Divya Chauhan

Medical Content Writer & Reviewer | 8 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Shivarth Ambit, Plot No. 142/2, Ramdas Road, Off SBR, Near Swati Bungalows, Ahmedabad, Gujarat - 380054

Country of origin: INDIA

Expiry on or after: January 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Sitagliptin: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a606023.html
Metformin: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a696005.html
About sitagliptin. (2022, February 15). NHS. https://www.nhs.uk/medicines/sitagliptin/about-sitagliptin/
Metformin: Uses, Interactions, Mechanism of Action. (n.d.). DrugBank Online. https://go.drugbank.com/drugs/DB00331
Metformin information. (2016, March 30). U.S. Food and Drug Administration. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/metformin-information

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Intellihealth Solutions Private Limited

Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.

CIN: U62099MH2019PTC320566

Telephone:09240250346

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Name: Kishor Kumar

Email: grievance-officer@truemeds.in

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