Sitanux M Xr 500 Tablet 10 is used to treat type 2 diabetes mellitus. It combines Sitagliptin (DPP-4 inhibitor) and Metformin (biguanide). This dual action improves insulin sensitivity, increases insulin release, and reduces liver glucose production. It is particularly effective for controlling post-meal blood sugar levels in adults.
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Sitanux M Xr 500 Tablet 10
Strip of 10 Units
Old MRP ₹180
MRP ₹168.75
₹84.21
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CompositionAbout Sitanux M Xr 500 Tablet 10
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Uses of Sitanux M Xr 500 Tablet 10
Sitanux M Xr 500 Tablet 10 is used to manage Type 2 Diabetes Mellitus in adults. It combines Sitagliptin (a DPP-4 inhibitor) and Metformin (a Biguanide) to enhance insulin release, reduce glucose production in the liver, and improve insulin sensitivity. This dual action helps maintain better blood sugar levels, reduce diabetes-related risks, and support overall metabolic health.
Directions for Use of Sitanux M Xr 500 Tablet 10
- Swallow the tablet whole with a glass of water.
- Do not crush, chew, or split the tablet.
- Always stick to the dose recommended by your doctor, and do not alter it on your own.
Route of Administration
Sitanux M Xr 500 Tablet 10 is taken orally.
Side Effects of Sitanux M Xr 500 Tablet 10
Sitanux M Xr 500 Tablet 10 may cause side effects like diarrhoea, headache, nausea, vomiting, weakness, gas, bloating, or upper respiratory infections. If these side effects persist or worsen, consult your doctor.
Managing the Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Sitanux M Xr 500 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
- Diarrhoea: Try taking Sitanux M Xr 500 Tablet 10 with food or milk to lessen this effect.
- Indigestion: If you have indigestion, take this medicine after meals to lessen this effect.
How Sitanux M Xr 500 Tablet 10 Works?
Sitanux M Xr 500 Tablet 10 has two active ingredients that work together to manage type 2 diabetes:
- Sitagliptin (50 mg): Sitagliptin maintains the levels of incretin hormones (GLP-1 and GIP) in your body. These hormones help stimulate insulin synthesis and release after meals, which aids in controlling post-meal blood sugar spikes.
- Metformin (500 mg): This component works by reducing the production of glucose in your liver, decreasing the absorption of glucose in your gut, and improving insulin sensitivity. This combined action results in lower blood sugar levels.
Safety Measures & Warnings
Pregnancy
Caution is advised while taking Sitanux M Xr 500 Tablet 10 if you are pregnant. It's best to consult your doctor before taking this medicine, as poorly managed blood sugars can harm the foetus.
Breastfeeding
The safety of this medicine during breastfeeding is not fully established. It's recommended to discuss this with your doctor before using Sitanux M Xr 500 Tablet 10 if you're breastfeeding.
Alcohol
You are advised to limit your alcohol intake while taking Sitanux M Xr 500 Tablet 10. Alcohol may increase the risk of lactic acidosis, a potential side effect of metformin.
Liver
If you have liver problems or elevated liver enzymes, caution is needed when taking Sitanux M Xr 500 Tablet 10. Before you start on this medication, discuss your liver health with your doctor.
Kidney
Sitanux M Xr 500 Tablet 10 is contraindicated in severe renal impairment conditions. If you have a history of kidney problems, it's crucial to consult your doctor before starting this medication.
Using Machines & Driving
No specific precautions exist regarding driving or operating heavy machinery while taking Sitanux M Xr 500 Tablet 10. However, if you feel dizzy or unwell after taking the medicine, avoid these activities.
Allergy
This medicine is contraindicated if you have a known hypersensitivity to metformin or sitagliptin. If you've had allergic reactions to similar medicines in the past, inform your doctor before starting this medication.
Children
Sitanux M Xr 500 Tablet 10 is meant for adult use and should not be given to children under 18 years of age unless prescribed by a doctor.
Older Patients
Older patients may need close monitoring while taking Sitanux M Xr 500 Tablet 10 due to potential side effects and co-existing health conditions. Your doctor will guide you based on your health status.
Interactions of Sitanux M Xr 500 Tablet 10
Drug-Drug Interactions
Sitanux M Xr 500 Tablet 10 interacts with the following medicines:
- Carbonic anhydrase inhibitors: Medications such as acetazolamide or methazolamide may interact with Sitanux M Xr 500 Tablet 10, increasing the risk of lactic acidosis due to metformin.
- Insulin and insulin secretagogues: When taken with Sitanux M Xr 500 Tablet 10, insulin and sulfonylureas like glimepiride or glibenclamide can cause low blood sugar (hypoglycaemia).
- Cationic medicines: Medicines like amiloride or quinidine, which are excreted via renal tubular secretion, may interact with Sitanux M Xr 500 Tablet 10, leading to an accumulation of metformin.
- Diuretics: Furosemide may increase plasma levels of metformin when used with Sitanux M Xr 500 Tablet 10, enhancing its blood glucose-lowering effect.
- Calcium channel blockers: Nifedipine may interact with Sitanux M Xr 500 Tablet 10, leading to increased absorption and peak concentration (Cmax) of metformin.
Drug-Food Interactions
None
Drug-Disease Interactions
Sitanux M Xr 500 Tablet 10 interacts with the following diseases:
- Renal impairment: Patients with severe renal impairment (eGFR < 30 mL/min/1.73 m²) should avoid Sitanux M Xr 500 Tablet 10 due to the risk of medicine accumulation and potential toxicity.
- Liver disease: Patients with liver disease should use Sitanux M Xr 500 Tablet 10 cautiously, as it may impact the metabolism of the medication.
- Congestive heart failure: Those with heart failure requiring medication should exercise caution when taking Sitanux M Xr 500 Tablet 10, as it may worsen their condition.
- Vitamin B12 deficiency: The metformin component in Sitanux M Xr 500 Tablet 10 can reduce Vitamin B12 levels; therefore, individuals with a deficiency should be monitored closely.
- Hypoxic states: Conditions like cardiovascular collapse (shock) can increase the risk of lactic acidosis, necessitating careful monitoring when using Sitanux M Xr 500 Tablet 10.
Dosage of Sitanux M Xr 500 Tablet 10
Daily Dose
You should take Sitanux M Xr 500 Tablet 10 as instructed by your doctor. The dosage can vary based on your individual health condition and response to the medication.
Over Dose
If you accidentally take more Sitanux M Xr 500 Tablet 10 than prescribed, you may experience symptoms like nausea, weakness, or diarrhoea. If these symptoms occur, kindly consult your doctor.
Missed Dose
If you miss a dose of Sitanux M Xr 500 Tablet 10, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one.
Storage
- Store Sitanux M Xr 500 Tablet 10 at a temperature not exceeding 30°C.
- Protect from light and moisture.
- Keep out of reach of children.
Diet & Lifestyle
- Incorporating at least 30 minutes of regular physical activity into your daily routine is essential for managing blood sugar levels effectively.
- Adopting a balanced diet that is low in sugar and high in fibre is crucial for controlling blood sugar spikes and enhancing the effectiveness of Sitanux M Xr 500 Tablet 10.
Fact Box
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Type 2 Diabetes |
| Drug Category | Glucose Regulator |
| Therapeutic Category | Antidiabetic |
Frequently Asked Questions (FAQs)
What is Sitanux M Xr 500 Tablet 10 used for?
Sitanux M Xr 500 Tablet 10 is used to manage blood sugar levels in adults with type 2 diabetes in conjunction with diet, exercise, and weight control.
How do the ingredients in Sitanux M Xr 500 Tablet 10 work?
Metformin reduces glucose production in the liver, intestinal glucose absorption, and improves insulin sensitivity. Sitagliptin helps increase insulin synthesis and release.
What happens if I miss a Dose of Sitanux M Xr 500 Tablet 10?
If it's almost time for your next dose, skip the one you missed. Don't double your dose to make up for the missed one.
Can I take Sitanux M Xr 500 Tablet 10 during pregnancy?
Sitanux M Xr 500 Tablet 10 is not advised during pregnancy as it may harm the unborn baby. Always consult your doctor before use.
Should I be aware of any side effects of Sitanux M Xr 500 Tablet 10?
Common side effects may include diarrhoea, upper respiratory tract infection, headache, nausea, vomiting, gas, and weakness. Consult your doctor if they persist or worsen.
Are there any precautions I should take while using Sitanux M Xr 500 Tablet 10?
Use this medicine with caution if you have heart problems, liver impairment, or vitamin B12 deficiency. Alcohol use should be minimised.
How should I store my Sitanux M Xr 500 Tablet 10?
Store your tablet at a temperature not exceeding 30°C, away from light, moisture, and children's reach.
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Manufacturer details
503/504 Hubtown solaris, Andheri (E), Mumbai 400069 INDIA
Country of origin: INDIA
Country of origin: INDIA
Expiry on or after: April 2026
In case of any issues, contact us:
support@truemeds.in|09240250346
Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071
References
- Sitagliptin: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a606023.html
- Metformin: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a696005.html
- About sitagliptin. (2022, February 15). NHS. https://www.nhs.uk/medicines/sitagliptin/about-sitagliptin/
- Metformin: Uses, Interactions, Mechanism of Action. (n.d.). DrugBank Online. https://go.drugbank.com/drugs/DB00331
- Metformin information. (2016, March 30). U.S. Food and Drug Administration. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/metformin-information
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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Intellihealth Solutions Private Limited
Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.
CIN: U62099MH2019PTC320566
Telephone:09240250346
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