Esomefol Sl Capsule 10

Leeford Healthcare

Strip of 10 Units

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MRP ~~₹190~~

₹94.81

₹19/Units

50.1% off

*MRP inclusive of all taxes

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Composition

Esomeprazole (40 Mg) + Levosulpiride (75 Mg)

Esomefol Sl Capsule 10 is used to reduce stomach acid and treat conditions like acid reflux, heartburn, and gastric ulcers. It helps protect the stomach lining and promotes healing by lowering acid production.

In addition, this capsule helps alleviate heartburn, acid reflux, sour taste in the mouth, and difficulty swallowing. These additional benefits are due to its dual action on reducing stomach acid production and preventing acid reflux.

Before you start taking this medication, consult your doctor for the correct dosage and frequency of use. Let your doctor know about any pre-existing conditions or ongoing medications before prescribing this medicine. If you experience any side effects while on this medication, notify your doctor immediately. To achieve the best results, take this medicine for the duration prescribed by your doctor.

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Esomefol Sl Capsule 10 is used for the following:

Managing gastroesophageal reflux disease
Controlling heartburn
Managing acid reflux
Counteracting sour taste in the mouth

Swallow the capsule whole with a glass of water.
Do not chew or crush the capsule.
It's best to take this medicine at least one hour before a meal, preferably in the morning or as prescribed by the doctor.
For specific advice on how to use this medicine, consult your doctor.

Esomefol Sl Capsule 10 is taken orally.

Esomefol Sl Capsule 10 may have the following common side effects:

Headache
Diarrhoea
Nausea
Abdominal pain
Constipation
Dry mouth
Dizziness
Flatulence: This means excessive gas in the stomach or intestines, leading to bloating and frequent belching or passing of wind.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Esomefol Sl Capsule 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking this capsule with food to possibly reduce this effect.
Abdominal pain: If you experience stomach pain after taking the capsule, you may want to take it after your meal.

Esomefol Sl Capsule 10 contains two active ingredients:

Esomeprazole (40 mg): This ingredient works by irreversibly blocking an enzyme system called the proton pump in the stomach's parietal cells that is responsible for acid production. By inhibiting this enzyme, esomeprazole effectively suppresses both basal and stimulated gastric acid secretion.
Levosulpiride (75 mg): Levosulpiride is a selective dopamine D2 receptor antagonist with prokinetic properties. It increases acetylcholine release, stimulating stomach and intestinal movement. Furthermore, it heightens lower oesophageal sphincter pressure to prevent reflux of stomach contents into the oesophagus.

Together, these two ingredients provide effective relief from GERD symptoms by both reducing stomach acid production and enhancing gastrointestinal motility.

Pregnancy

Caution is advised while taking Esomefol Sl Capsule 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Esomefol Sl Capsule 10 during breastfeeding. Always consult your doctor before using this medicine if you are breastfeeding.

Alcohol

Drinking alcohol is contraindicated while taking Esomefol Sl Capsule 10 as it can possibly intensify some side effects. Share your alcohol consumption history with your doctor before starting this medicine.

Liver

Esomefol Sl Capsule 10 should be used with caution if you have severe liver impairment. Always discuss with your doctor if you have liver problems before using this medicine.

Kidney

If you have a history of any kidney problems, caution is advised before using Esomefol Sl Capsule 10. Consult your doctor before use.

Using Machines & Driving

Esomefol Sl Capsule 10 may cause dizziness. Be careful while driving or operating machinery until you know how the medicine affects you.

Allergy

Esomefol Sl Capsule 10 is contraindicated if you have known hypersensitivity to esomeprazole, levosulpiride or any other ingredients in the formulation.

Children

Esomefol Sl Capsule 10 should not be given to children under 18 years of age without medical supervision. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Esomefol Sl Capsule 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Esomefol Sl Capsule 10 interacts with the following medicines:

Cardiac glycosides: Esomeprazole may increase digoxin levels in the blood, potentially enhancing digoxin's effects.
Immunosuppressants: Esomeprazole may increase blood levels of tacrolimus, which could lead to more side effects.
Antiplatelet agents: The effectiveness of clopidogrel may be reduced when taken with esomeprazole.
Cancer medications: Esomeprazole may increase methotrexate levels, potentially leading to toxicity.
Central Nervous System (CNS) Depressants: Levosulpiride can enhance the sedative effect of CNS depressants such as benzodiazepines and opioids.

Drug-Food Interactions

Esomefol Sl Capsule 10 has interactions with certain foods:

High-fat meals: These can delay the absorption of levosulpiride, thus reducing its effect.

Drug-Disease Interactions

Esomefol Sl Capsule 10 interacts with the following diseases:

Liver Disease: This medicine should be used with caution in individuals with severe liver impairment.
Pheochromocytoma: This capsule is contraindicated in patients with pheochromocytoma, a type of adrenal gland tumour.
Parkinson's Disease: Patients with Parkinson's disease should use levosulpiride with caution due to the risk of worsening symptoms.
Pituitary Tumours: Levosulpiride can increase prolactin levels, which could stimulate the growth of prolactin-releasing pituitary tumours.

Daily Dose

The recommended dose of this capsule should be taken as directed by your doctor. The dosage may vary depending on your health status and response to the medicine. Always adhere to the prescribed dosage and never alter it without consulting your doctor.

Over Dose

In the event of an overdose, you might experience more intense common side effects like headache, diarrhoea, or nausea. If these symptoms persist, consult your doctor.

Missed Dose

If you forget to take your dose of this capsule, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never modify your dosage without discussing it with your doctor.

Store your Esomefol Sl Capsule 10 in a cool, dry place with temperatures not exceeding 30°C.
Keep the medicine away from direct sunlight and moisture.
Always keep it out of reach of children.
Make sure you use this medicine before its expiry date.

Try to avoid spicy or fatty foods, which can trigger acid reflux and worsen the symptoms of GERD.
Encourage regular light exercise, like walking, which can aid digestion and reduce the onset of GERD symptoms.

Fact Box

Available Dosage Types	Capsule
Habit Forming	No
Ailment	Gastroesophageal Reflux Disease
Drug Category	Proton Pump Inhibitor, Dopamine Antagonist
Therapeutic Category	Gastrointestinal Agent

What is Esomefol Sl Capsule 10 used for?

It's used to manage GERD, a condition causing heartburn, acid reflux, and difficulty swallowing due to stomach acid flowing back into the food pipe.

How does Esomefol Sl Capsule 10 work?

It contains esomeprazole and levosulpiride. Esomeprazole decreases stomach acid production, while levosulpiride enhances stomach and intestinal movement, preventing acid reflux.

How should I take Esomefol Sl Capsule 10?

The capsule should be swallowed whole, preferably one hour before a meal or as prescribed by the doctor; it should not be chewed or crushed. Consult your doctor for duration.

Can everyone take Esomefol Sl Capsule 10?

No, individuals with allergies to esomeprazole, levosulpiride or any ingredients in the capsule, or those with certain health conditions like pheochromocytoma, should avoid taking this medicine.

What are the common side effects of Esomefol Sl Capsule 10?

Common side effects include headache, diarrhoea, nausea, abdominal pain, flatulence, constipation, dry mouth and dizziness. Consult your doctor if you experience any side effects.

Can I take other medicines while using Esomefol Sl Capsule 10?

Some medications may interact with esomeprazole or levosulpiride, altering their effect. Always consult your doctor before starting any new medication.

Can pregnant or breastfeeding women take Esomefol Sl Capsule 10?

Caution is advised while using this medicine during pregnancy or breastfeeding. It should only be used if the benefits outweigh the risks after consulting a doctor.

Last Updated On 13 May. 2025 | 11:15AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Divya Chauhan

Medical Content Writer & Reviewer | 7 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Leo House, Shaheed Bhagat Singh Nagar, Dugri Dhandra Road, Near Joseph School Ludhiana PB 141002 IN

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

HIGHLIGHTS OF PRESCRIBING INFORMATION. NEXIUM (esomeprazole magnesium) delayed-release capsules. (2014). U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022101s014021957s017021153s050lbl.pdf
Esomeprazole 40 mg gastro-resistant tablets Patient information leaflet (PIL) (emc). (n.d.). electronic medicines compendium (emc). https://www.medicines.org.uk/emc/files/pil.2326.pdf
Esomeprazole: MedlinePlus drug information. (n.d.). MedlinePlus Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a699054.html
About esomeprazole. (2022, January 13). nhs.uk. https://www.nhs.uk/medicines/esomeprazole/about-esomeprazole/
Levosulpiride-induced neurological adverse effects: A prospective study from a tertiary care center. (2020, March). PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061517/
Levosulpiride. (n.d.). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB16021

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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