Axegliptin M 500 Tablet 10 is used to manage type 2 diabetes in adults by helping control blood sugar levels.
It contains teneligliptin and metformin, two medicines that work together to lower blood sugar. Take it with food as prescribed to help reduce stomach upset.
Regular balanced meals with controlled carbohydrate intake, staying physically active, keeping to a healthy weight, and routine blood sugar checks support better control alongside this medicine.
Before taking this medicine, tell your doctor about any kidney, liver, or heart problems, or a history of alcohol dependence. Tell your doctor if you feel unusually tired, have persistent vomiting, or notice signs of low blood sugar such as shakiness, sweating, or confusion.
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Axegliptin M 500 Tablet 10
Strip of 10 Units
MRP ₹152.81
₹99.33
₹9.93/Units
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CompositionAbout Axegliptin M 500 Tablet 10
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Uses of Axegliptin M 500 Tablet 10
Axegliptin M 500 Tablet 10 is used in adults with type 2 diabetes to improve blood sugar control, combining two medicines when a single therapy is not enough alongside proper diet and regular exercise.
Uses of Axegliptin M 500 Tablet 10 are:
- Type 2 Diabetes: Helps control fasting and after-meal blood sugar levels.
- Complication Prevention: Better blood sugar control helps reduce the long-term risk of kidney, nerve, and heart complications.
- Combination Therapy: Suitable when a single antidiabetic medicine does not provide adequate control.
Directions for Use of Axegliptin M 500 Tablet 10
Follow these instructions while taking Denedel M Tablet:
- Swallow the tablet whole with a glass of water.
- Avoid crushing or chewing the tablet.
- Do not take more than the recommended dose without consulting your doctor.
- It's important not to stop taking this medicine without speaking to your doctor first.
Route of Administration
Axegliptin M 500 Tablet 10is taken orally.
Side Effects of Axegliptin M 500 Tablet 10
Axegliptin M 500 Tablet 10 may cause side effects, but not everyone gets them.
Possible side effects of Axegliptin M 500 Tablet 10 include:
- Digestive: Diarrhoea, feeling sick (nausea), and vomiting.
- Musculoskeletal: Joint pain.
- General: Vitamin B12 deficiency with long-term use.
If side effects do not improve or become serious, speak to your doctor right away.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Denedel M Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
- Abdominal pain or discomfort: Take this medicine with your evening meal to lessen this effect.
- Flatulence: Try taking Axegliptin M 500 Tablet 10with food to reduce gas production.
How Axegliptin M 500 Tablet 10 Works?
Axegliptin M 500 Tablet 10contains two active ingredients:
- Metformin Hydrochloride (500 mg): As a biguanide antihyperglycemic agent, metformin reduces glucose in the liver, decreases glucose absorption in the intestines, and enhances insulin sensitivity. This combination helps to lower blood sugar levels throughout the day.
- Teneligliptin Hydrobromide Hydrate (20 mg): Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It operates by slowing down the breakdown process of incretin hormones like GLP-1 and GIP. This action boosts their effects, leading to increased insulin production when blood sugar is high and decreased glucose production by the liver.
Together, these ingredients provide comprehensive control over blood sugar levels in adults with type 2 diabetes.
Safety Measures & Warnings
Pregnancy
Caution is advised while taking Axegliptin M 500 Tablet 10if you are pregnant. It's best to consult your doctor before taking this medicine.
Breastfeeding
If you are breastfeeding, please consult your doctor before starting Denedel M Tablet.
Alcohol
It's important to limit alcohol consumption while taking Denedel M Tablet, as it might enhance the risk of lactic acidosis with metformin.
Liver
If you have any liver health issues, discussing them with your doctor before starting Axegliptin M 500 Tablet 10is advisable.
Kidney
Axegliptin M 500 Tablet 10should be used cautiously if you have any kidney health issues. Your doctor will guide you based on your health status.
Use In Driving And Operating Machinery
Axegliptin M 500 Tablet 10doesn't usually affect your ability to operate machinery or drive. However, avoid driving or operating heavy machines if you experience side effects like dizziness or weakness.
Allergy
If you have ever had an allergic reaction to metformin or teneligliptin, do not take Denedel M Tablet.
Children
Axegliptin M 500 Tablet 10is intended for adult use. It should not be given to children under 18 years of age.
Older Patients
Older patients should take Axegliptin M 500 Tablet 10under medical supervision as they may be more susceptible to its effects. Your doctor will guide you based on your health status.
Interactions of Axegliptin M 500 Tablet 10
Drug-Drug Interactions
Axegliptin M 500 Tablet 10interacts with the following medicines:
- Cationic Medicines: Medicines like amiloride, digoxin, and morphine can slow down the elimination of metformin from your body. This could lead to a buildup of metformin, increasing the risk of side effects.
- Diuretics: Certain medications like furosemide could decrease kidney function and increase the risk of lactic acidosis when you're taking metformin.
- Glucose-Altering Medicines: Certain medications, such as isoniazid, can interfere with blood sugar levels, influencing the effectiveness of Denedel M Tablet.
Drug-Food Interactions
There are no known specific food interactions with Denedel M Tablet.
Drug-Disease Interactions
Axegliptin M 500 Tablet 10interacts with certain diseases:
- Kidney Disease: If you have kidney disease, your body may not be able to clear metformin properly. This can increase medicine levels in your body and cause side effects.
- Liver Disease: Metformin is broken down by the liver. If you have liver disease, it may affect how well your body breaks down and removes this medicine.
- Heart Disease: If you have a condition where your heart can't pump blood as well as it should (heart failure), taking Axegliptin M 500 Tablet 10might increase your risk of lactic acidosis.
Dosage of Axegliptin M 500 Tablet 10
Daily Dose
The daily dose of Axegliptin M 500 Tablet 10should be taken as prescribed by your doctor. The dosage can vary based on individual factors, such as the severity of your condition and how you respond to the medication. It's critical to adhere to the prescribed dosage and not exceed it without consulting your doctor.
Over Dose
Overdosing on Axegliptin M 500 Tablet 10might lead to common side effects like nausea, abdominal pain, or diarrhoea. If you suspect an overdose, reach out to your doctor for guidance.
Missed Dose
If you've missed a dose of Denedel M Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.
Storage
- Store Axegliptin M 500 Tablet 10at room temperature.
- Keep the medicine in a cool, dry place, away from direct sunlight.
- Ensure the storage area is moisture-free to maintain the tablet's effectiveness.
- Always keep this medicine out of reach of children.
Special Dietary And Lifestyle Recommendation
- Since Axegliptin M 500 Tablet 10is used to manage type 2 diabetes, incorporating a balanced diet low in sugar and high in fibre can help control blood glucose levels.
- Regular physical exercise, such as brisk walking or cycling, will also help maintain healthy blood sugar levels and improve overall health.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Type 2 diabetes mellitus |
| Drug Category | Biguanide Antihyperglycemic, DPP-4 Inhibitor |
| Therapeutic Category | Antidiabetic |
Frequently Asked Questions (FAQs)
Can I stop taking Axegliptin M 500 Tablet 10if I feel better?
No, you shouldn't stop taking Axegliptin M 500 Tablet 10without consulting your doctor. This medicine helps manage your blood sugar levels continuously.
What happens if I miss a dose of Denedel M Tablet?
If you miss a dose, take it as soon as you remember. However, skip the missed dose if it's nearly time for the next one. Don't double up your dosage to compensate for the missed one.
How long does it take for Axegliptin M 500 Tablet 10to start working?
The effect on blood sugar control can generally be noticed within two weeks, but full benefits may take 2 to 3 months to become evident. In general, it depends on your health status and the severity of your condition.
Can I take a Axegliptin M 500 Tablet 10during pregnancy or breastfeeding?
Axegliptin M 500 Tablet 10is not recommended during pregnancy or breastfeeding. Always consult your doctor for advice on this matter.
What should I avoid while taking the Denedel M Tablet?
It's advisable to avoid excessive alcohol consumption as it can increase the risk of lactic acidosis, especially when combined with metformin.
Can Axegliptin M 500 Tablet 10cause side effects?
Yes, common side effects include diarrhoea, nausea, and vomiting among others. If any of these persist or worsen, consult your doctor immediately.
Are there specific foods I should avoid while taking Denedel M Tablet?
No specific food restrictions are noted for this medication, but maintaining a balanced diet is always beneficial in managing type 2 diabetes.
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Manufacturer details
54, Sir Mathuradas Vasanji Rd, Hanuman Nagar, Andheri East, Mumbai, Maharashtra 400053
Country of origin: INDIA
Country of origin: INDIA
Expiry on or after: January 2027
In case of any issues, contact us:
support@truemeds.in|09240250346
Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071
References
- Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.-c). DrugBank. https://go.drugbank.com/drugs/DB00331
- Teneligliptin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB11950
- U.S. National Library of Medicine. (2021). METFORMIN HYDROCHLORIDE tablet, film coated [Candela Healthcare]. DailyMed. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b857eccf-b9ff-45ba-8241-f47f5caada2a. Accessed 1 April 2024.
- Yamada, Y., & Kato, T. (2021). Teneligliptin: A DPP-4 inhibitor for the treatment of type 2 diabetes. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 14, 2041–2058. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805719/. Accessed 1 April 2024.
- U.S. Food and Drug Administration. (2006). Metformin hydrochloride tablet, film coated [label]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf. Accessed 1 April 2024.
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.
CIN: U62099MH2019PTC320566
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