Strip of 10 Units
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CompositionEternex M 500 Tablet 10 is used to manage Type 2 Diabetes Mellitus when diet and exercise alone do not provide adequate blood sugar control. This medicine combines Teneligliptin (a DPP-4 inhibitor) and Metformin 500 mg (a biguanide) in a Sustained Release (SR) formulation. This dual action works by improving the body's insulin sensitivity, stimulating the pancreas to release insulin, and lowering glucose production by the liver, thereby achieving better glycemic control.
Eternex M 500 Tablet 10 is used to manage type 2 diabetes mellitus by helping control blood sugar levels. It works by improving insulin sensitivity and lowering blood glucose, providing better glycemic control when diet and exercise alone are not sufficient.
Swallow the tablet whole with a glass of water during a meal.
Do not split, crush, or chew the tablet; it must be swallowed whole.
Never exceed the recommended dose without consulting your doctor.
It's crucial not to stop taking this medicine without speaking to your doctor first.
Eternex M 500 Tablet 10 is taken orally.
Eternex M 500 Tablet 10 may cause side effects such as diarrhoea, nausea, vomiting, abdominal discomfort, headache, and indigestion. If these persist, consult your doctor.
Most side effects are temporary and generally harmless which resolve upon discontinuing the use of Eternex M 500 Tablet 10. However, if you experience any serious side effects or worsening of any symptoms, please consult your doctor.
Here are a few tips for managing common side effects:
Diarrhoea: You could try taking your medication with food.
Indigestion: If you're experiencing indigestion, consider taking this medicine after meals to lessen this effect.
Eternex M 500 Tablet 10 combines two active ingredients:
Metformin (500 mg): As a biguanide antihyperglycemic agent, metformin enhances glucose tolerance in individuals with type 2 diabetes. It accomplishes this by reducing glucose production in the liver and decreasing glucose absorption in the intestines. Additionally, it helps increase peripheral glucose uptake and utilisation, thereby improving insulin sensitivity.
Teneligliptin (20 mg): Classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor, teneligliptin works by slowing down the inactivation of incretin hormones. This process increases their concentrations in the bloodstream, leading to reduced fasting and postprandial glucose levels in a glucose-dependent manner among patients with type 2 diabetes.
If you're pregnant, it's best to be cautious when taking Eternex M 500 Tablet 10. Discuss this with your doctor before starting this medication.
Metformin is known to be excreted into human milk, while the effects of Teneligliptin on breastfed infants are unknown. If you're breastfeeding, consult your doctor before using this medicine.
Combining alcohol with this medicine could increase the risk of lactic acidosis, a serious medical condition. It's advised that you limit your alcohol intake while on this medication.
If you have liver issues, use Eternex M 500 Tablet 10 with caution. This medicine may affect liver function. Before starting, discuss your liver health with your doctor.
This medicine is not used in patients with severe renal impairment. If you have kidney problems, it's important to consult your doctor before taking this medicine.
No specific precautions are necessary when driving or using machines while taking Eternex M 500 Tablet 10.
If you know you're allergic to metformin, teneligliptin or any of the other ingredients in this medicine, avoid using Eternex M 500 Tablet 10.
The safety and effectiveness of Eternex M 500 Tablet 10 for children have not been established. Always consult your doctor before giving this medicine to individuals under 18 years of age.
Older patients should take Eternex M 500 Tablet 10 under medical supervision, as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.
Eternex M 500 Tablet 10 may interact with the following medicines:
CYP3A4 or P-gp inhibitors like ketoconazole or atazanavir may interact with Eternex M 500 Tablet 10, potentially increasing the plasma concentrations of teneligliptin.
Anticoagulants such as phenprocoumon or acenocoumarol may have reduced effects when taken with Eternex M 500 Tablet 10 due to metformin's influence.
Thyroid hormone supplements: Levothyroxine's effectiveness can be decreased by the presence of this medicine.
ACE Inhibitors like enalapril or lisinopril, when used with Eternex M 500 Tablet 10, can increase the hypoglycemic effect.
None
Eternex M 500 Tablet 10 can interact with the following diseases:
Renal Disease: Severe renal impairment can result in adverse reactions when this medicine is used.
Hepatic Impairment: This medicine should be used with caution in patients with liver disease.
Metabolic Acidosis: Patients diagnosed with metabolic acidosis, including diabetic ketoacidosis, should avoid using this medicine.
It's crucial that you take your daily dose of Eternex M 500 Tablet 10 as prescribed by your doctor. Dosage may vary depending on individual factors such as your health condition and how you respond to the medicine. Always stick to the dosage recommended by your doctor, and never alter it without seeking medical advice.
In the case of an overdose, you might experience common side effects in a more pronounced way. However, it's always better not to panic and calmly inform your doctor about the situation. Remember, following the prescribed dosage helps prevent such situations.
If you've missed a dose of Eternex M 500 Tablet 10, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Don't adjust your dosage or frequency without consulting your doctor.
Store Eternex M 500 Tablet 10 in a dry place below 30°C.
Shield it from light to maintain its effectiveness.
Keep this medicine unreachable for children, ensuring their safety.
Always check the expiration date before using the tablet.
Incorporate a balanced diet rich in fibre and low in simple sugars to help manage your blood sugar levels.
Regular physical activity like walking or yoga can also support glucose control, but always consult your doctor before starting any new exercise regimen.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Type 2 Diabetes Mellitus |
| Drug Category | Biguanide Antihyperglycemic, DPP-4 Inhibitor |
| Therapeutic Category | Antidiabetic |
This medicine is used to manage type 2 diabetes in adults when single therapy with either metformin or teneligliptin doesn't effectively control blood sugar.
Metformin in this tablet reduces glucose production in the liver, enhances glucose uptake and use, while teneligliptin increases insulin release and reduces glucagon secretion.
It's best to consult your doctor. There aren't sufficient studies about its use during pregnancy, so it should be used only if clearly needed.
Metformin is known to pass into human milk, but the effect on a breastfed infant is unknown. Therefore, consult with your doctor before using this medicine on such occasions.
The safety and effectiveness of this medicine haven't been established for paediatric use. It's meant for adults and should be given to children only if prescribed by a doctor.
Overdose can lead to serious conditions like lactic acidosis. Immediate medical attention is required in case of an overdose.
Severe and disabling joint pain can occur with DPP-4 inhibitors like teneligliptin. If you experience severe joint pain, consult your doctor.
Check out Editorial Policy
Medlineplus. (n.d.). Metformin. Retrieved from https://medlineplus.gov/druginfo/meds/a696005.html
National Center for Biotechnology Information. (2013). Efficacy and safety of teneligliptin, a novel dipeptidyl peptidase-4 inhibitor, in Korean patients with type 2 diabetes mellitus: a 24-week multicentre, randomized, double-blind, placebo-controlled phase III trial. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650886/
U.S. Food and Drug Administration. (2006). FDA Approved Drug Products: Metformin Hydrochloride. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf
PubChem. (n.d.-aj). Metformin. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/metformin
PubChem. (n.d.-az). Teneligliptin. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Teneligliptin
Teneligliptin: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB11950
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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