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CompositionRosumac F Tablet is used to manage severe mixed dyslipidemia (high cholesterol and triglycerides) and reduce cardiovascular risk. It combines Rosuvastatin (a statin, lowering cholesterol production) and Fenofibrate (a PPARα activator, increasing fat breakdown). This dual mechanism is highly effective for conditions like primary hypercholesterolaemia and severe hypertriglyceridaemia, preventing events like heart attacks and strokes.
Rosumac F Tablet is effective in managing dyslipidemia, including high cholesterol, triglycerides, and mixed dyslipidemia. It helps prevent cardiovascular events like heart attacks and strokes, reduces the need for revascularization procedures, and improves overall lipid balance.
To use Rosumac F Tablet correctly, follow the guidelines below:
Swallow the whole tablet with a glass of water.
Avoid crushing or chewing the tablet.
Administer this medicine at the same time each day for best results.
Never exceed the recommended dosage without consulting your doctor.
It's crucial not to discontinue this medicine without speaking to your doctor first.
Rosumac F Tablet is taken orally.
Rosumac F Tablet might cause headache, muscle pain, abdominal pain, weakness or lack of energy, and nausea. If you experience any of these symptoms for an extended period, consult your healthcare provider.
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Rosumac F Tablet . However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some tips for managing common side effects:
Abdominal pain: Try taking Rosumac F Tablet with food or milk.
Headache: If you have a headache after taking this medicine, consider taking it at night.
Rosumac F Tablet consists of two components:
Fenofibrate (67 mg): This ingredient activates a receptor called peroxisome proliferator-activated receptor alpha (PPARα), which regulates genes involved in lipid metabolism. The activation of PPARα enhances the activity of lipoprotein lipase, an enzyme that breaks down triglycerides. It also reduces ApoC-III levels, a protein that inhibits lipoprotein lipase. The result of these actions is enhanced clearance of triglycerides from the blood and increased HDL cholesterol levels.
Rosuvastatin (10 mg): This ingredient works by competitively inhibiting HMG-CoA reductase, an enzyme responsible for cholesterol production in the liver. By blocking this enzyme, rosuvastatin increases the number of LDL receptors on liver cells which aids in removing LDL cholesterol from the blood. It also reduces total cholesterol, LDL cholesterol, ApoB, and nonHDL cholesterol while moderately increasing HDL cholesterol and reducing triglycerides.
Rosumac F Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.
Rosumac F Tablet is contraindicated for breastfeeding/lactating women. Consult your doctor to understand the potential risks and benefits.
Caution is advised while consuming alcohol when taking Rosumac F Tablet as it may alter the effectiveness of the medicine. It's best to discuss this with your doctor.
Caution is advised while taking Rosumac F Tablet in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Rosumac F Tablet. This medicine may affect liver function.
Caution is advised before using Rosumac F Tablet if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.
No specific precautions are required while using machines or driving after taking Rosumac F Tablet. However, if you feel dizzy or unwell after taking this medicine, avoid driving or operating heavy machinery.
If you have a known allergy to fenofibrate, rosuvastatin, or any other ingredients present in Rosumac F Tablet, refrain from using it and consult your doctor for alternatives.
Rosumac F Tablet is not recommended for use in children under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older patients should take Rosumac F Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.
Rosumac F Tablet interacts with the following medicines:
Oral Anticoagulants: The medication might increase the effect of oral anticoagulants like warfarin, leading to an increased risk of bleeding.
Other Fibrates: Concomitant use with other fibrates such as gemfibrozil might raise the chance of muscle damage.
Bile Acid Sequestrants: Medications like cholestyramine can decrease the absorption of fenofibrate, a component of Rosumac F Tablet.
Drinking grapefruit juice while taking this medicine might increase rosuvastatin levels in your body and could potentially lead to increased side effects.
Rosumac F Tablet interacts with the following diseases:
Active Liver Disease: People with active liver disease or unexplained persistent liver enzyme elevations should avoid this medicine as it could worsen their condition.
Severe Renal Impairment: Those with severe renal impairment might experience an increased risk of side effects, as the medicine is metabolised through the kidneys.
You should take Rosumac F Tablet as prescribed by your doctor. Remember, the dosage may vary based on your condition and response to treatment. Always consult your doctor before changing dosage.
Overdosing on Rosumac F Tablet may cause common side effects to worsen. If you suspect you've taken too much, don't panic but do inform your doctor and follow their advice.
If you miss a dose of Rosumac F Tablet, take it when you remember. However, if it's nearly time for the next dose, skip the missed one. Never double-dose without consulting your doctor.
Store your Rosumac F Tablet in a tightly closed container, away from direct sunlight and moisture.
The ideal temperature for storage is below 30°C.
Keep it out of reach and sight of children.
Always check the expiry date before use.
Incorporate fibre-rich foods such as whole grains, fruits, and vegetables into your diet as they can help manage high cholesterol levels.
Exercise regularly. Physical activities like walking, cycling, or swimming can help improve your overall cholesterol levels and cardiovascular health.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Hypercholesterolaemia, Hypertriglyceridaemia |
| Drug Category | PPARα Activator, HMG-CoA Reductase Inhibitor |
| Therapeutic Category | Lipid Regulating Agents |
Rosumac F Tablet is employed to manage abnormal lipid levels in the blood, which may help decrease the risk of heart attack, stroke, and arterial revascularisation procedures.
It consists of two ingredients. Fenofibrate reduces "bad" cholesterol and raises "good" cholesterol, while rosuvastatin blocks an enzyme involved in making cholesterol in the liver, reducing overall cholesterol levels.
Yes, you can take Rosumac F Tablet with or without food. However, taking it with food may enhance its absorption.
Individuals with known allergies to fenofibrate or rosuvastatin, active liver disease, severe kidney impairment, or those who are pregnant or breastfeeding should avoid this medicine.
Common side effects include headache, muscle pain, abdominal pain, weakness, and nausea. Serious but rare effects may include muscle damage, liver enzyme abnormalities and severe skin reactions.
Store your tablets at room temperature below 30°C in a closed container away from light and moisture. Keep them out of reach of children.
Yes, it may interact with oral anticoagulants and other fibrates. Fenofibrate could decrease absorption of bile acid sequestrants. Certain medicines might increase rosuvastatin levels.
Check out Editorial Policy
AstraZeneca. (2003). CRESTOR. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021366s016lbl.pdf
Rosuvastatin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01098
HIGHLIGHTS OF PRESCRIBING INFORMATION. (2018). [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021656s029lbl.pdf
Fenofibrate: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01039
Martin, P. D., Dane, A. L., Schneck, D. W., & Warwick, M. J. (2003). An open-label, randomized, three-way crossover trial of the effects of coadministration of rosuvastatin and fenofibrate on the pharmacokinetic properties of rosuvastatin and fenofibric acid in healthy male volunteers. Clinical Therapeutics, 25(2), 459–471. https://doi.org/10.1016/s0149-2918(03)80089-9
Barkate, H., Patel, P., Shah, D., & Vyas, F. (2018). Comparison of efficacy and safety of fixed dose combination of rosuvastatin and choline fenofibrate to fixed dose combination of rosuvastatin and fenofibrate in patients of mixed dyslipidaemia: A randomized, open-label, multicentre clinical trial in Indian population. Indian Journal of Endocrinology and Metabolism, 22(5), 627. https://doi.org/10.4103/ijem.ijem_321_16
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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