Fenofibrate + Rosuvastatin
Hypolipidemic DrugsUses of Fenofibrate + Rosuvastatin
Fenofibrate + Rosuvastatin is a combination medicine used to lower high cholesterol and triglyceride levels in the blood.
This combination is commonly used for:
• High cholesterol (hyperlipidaemia): Lowers LDL (bad) cholesterol levels in the blood.
• High triglycerides: Reduces triglyceride levels and raises HDL (good) cholesterol.
• Reducing cardiovascular risk: Helps lower the risk of heart disease and stroke linked to abnormal cholesterol levels.
Side effects of Fenofibrate + Rosuvastatin
- Constipation
- Nausea
- Abdominal pain
- Muscle pain
- Weakness
- Dizziness
How Fenofibrate + Rosuvastatin works
Fenofibrate + Rosuvastatin works through two actions that lower cholesterol and triglycerides.
Rosuvastatin is a statin. It blocks an enzyme called HMG-CoA reductase, which the liver needs to produce cholesterol. This slows down cholesterol production, reducing its build-up on artery walls and lowering the risk of blockages.
Fenofibrate is a fibrate. It boosts the body's natural process for clearing cholesterol and triglycerides from the blood.
Together, the two medicines help regulate cholesterol and triglyceride levels, supporting overall cardiovascular health.
Certified content
Written By
MBBS
Reviewed By
MBBS, DNB (OBGY)
Expert Advice
Dosage Forms Available
- Fenofibrate + Rosuvastatin can be taken orally (tablet).
Age And Dose Restrictions
- This combination is meant to be used for adults only. It is not recommended for children.
Contraindications
- It is contraindicated in patients with a history of hypersensitivity to fenofibrate or rosuvastatin.
Medications To Avoid With This Drug
- Avoid taking immunosuppressants (cyclosporin), HIV medications (lopinavir/ritonavir or atazanavir/ritonavir), coumarin anticoagulants, other lipid-lowering medications (gemfibrozil), and bile acid resin (cholestyramine). These medications may alter the safety and effectiveness of this combination.
Overdose And Missed Dose
- Taking more than the prescribed dose may worsen side effects or cause them to become severe, requiring emergency care in a hospital. If you suspect an overdose, seek medical attention immediately.
- If you miss a dose of Fenofibrate + Rosuvastatin, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
Management Of Side Effects
- Take this combination with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.
Use In Pregnancy And Lactation
- Caution is advised during pregnancy and breastfeeding.
Caution In Other Conditions
- Caution is advised in older adults and in patients with preexisting gallbladder disease, skeletal muscle disorders, hypothyroidism, type 2 diabetes and severe kidney or liver problems.
Special Dietary And Lifestyle Recommendation
- Avoid drinking alcohol with this combination due to the increased risk of muscle problems.
- Continue taking this combination as prescribed by a doctor.
- Limit saturated and trans fats while taking lipid-lowering medications.
Frequently asked questions
1. How much time does Fenofibrate + Rosuvastatin take to work?
This combination may show lipid-lowering effects within a few weeks, but their full impact on cholesterol and triglyceride levels may take several weeks to months.
2. Does Fenofibrate + Rosuvastatin increase blood sugar levels?
This combination may increase blood sugar levels.
3. Is Fenofibrate + Rosuvastatin a habit-forming medicine?
No, this combination is not habit-forming and is generally safe when used as directed.
4. Can I drive after taking Fenofibrate + Rosuvastatin?
This combination may cause dizziness. Do not drive, operate machinery, or do other activities that require mental alertness or coordination until you know how this medication affects you.
5. Is Fenofibrate + Rosuvastatin available over the counter, or do I need a prescription?
This combination usually require a prescription and is unavailable over the counter.
6. Does Fenofibrate + Rosuvastatin affect fertility?
This combination may cause fertility problems. If you have concerns about fertility, it is recommended to consult with a doctor for personalised advice.
7. Does Fenofibrate + Rosuvastatin affect blood pressure?
This combination generally do not have a significant impact on blood pressure.
8.Can Fenofibrate + Rosuvastatin cause joint pain?
Joint pain is not a common side effect of this combination. However, this combination may aggravate the existing muscle pain.
9. Does Fenofibrate + Rosuvastatin combination cause fatigue?
Yes, this combination can make you feel extremely tired and weak.
10. What is Fenofibrate + Rosuvastatin used for?
Fenofibrate + Rosuvastatin is used to treat mixed dyslipidemia by lowering high triglycerides and LDL (bad cholesterol) and increasing HDL (good cholesterol). It is prescribed when diet and lifestyle changes are not enough. This combination helps reduce the risk of heart attacks, strokes, and other heart-related complications, especially in patients with high cholesterol and high triglyceride levels.
List of medicines for Fenofibrate + Rosuvastatin
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