Glz Plus Tablet 15

Alembic Pharmaceuticals Ltd

Strip of 15 Units

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MRP ~~₹184.6~~

₹147.68

₹12.31/Units

20% off

*MRP inclusive of all taxes

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Prescription required for this medicine

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Composition

Gliclazide (80 Mg) + Metformin (500 Mg)

GLZ Plus Tablet is used to manage type 2 diabetes by controlling blood sugar levels. It combines two medications that help improve insulin sensitivity and reduce glucose production, contributing to better blood sugar regulation.

Apart from its principal use, this tablet is also helpful when treatment with either of its components does not adequately control blood sugar levels. In such cases, this medication can provide a more comprehensive approach to managing blood sugar levels.

You should take this medicine as directed by your doctor. Before starting this medication, it's crucial to inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medicine, notify your doctor immediately. For the best results, continue taking the tablet for the duration prescribed by your doctor.

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GLZ Plus Tablet is used for the following conditions:

Management of type 2 diabetes mellitus in adults
Improvement of blood sugar control when either gliclazide or metformin alone does not provide adequate results

Here's how you should take your GLZ Plus Tablet:

Swallow the tablet whole with a glass of water.
Avoid chewing, crushing, or splitting the tablet.
Always take this medicine with meals.
Do not exceed the recommended dose without consulting your doctor.
Remember, it's crucial not to discontinue this medicine without speaking to your doctor first.

GLZ Plus Tablet is taken orally.

GLZ Plus Tablet may have the following common side effects:

Gastrointestinal disturbances: This could mean you might experience upset stomach, diarrhoea, or vomiting.
Headache
Dizziness
Hypoglycaemia: This is a condition where your blood sugar levels drop below normal. Symptoms can include weakness, shaking, sweating, and confusion.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolves on discontinuing the use of GLZ Plus Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Gastrointestinal disturbances: Try taking GLZ Plus Tablet with your meals to help reduce these symptoms.
Hypoglycaemia: You should consider having a regular eating schedule when taking this medication to avoid blood sugar dips.

GLZ Plus Tablet is a blend of two active ingredients:

Gliclazide (80 mg): As a sulfonylurea, gliclazide stimulates insulin release from the pancreas's beta cells. It does this by binding to specific receptors on these beta cells and triggering a series of events that lead to increased insulin release. Insulin is a hormone that helps lower blood glucose levels.
Metformin (500 mg): Metformin belongs to the class of biguanides. It works mainly by reducing glucose production in the liver and improving insulin sensitivity in peripheral tissues like muscles. By activating a specific enzyme, metformin helps regulate cellular energy balance, promotes glucose uptake in muscles, reduces intestinal glucose absorption, and facilitates glucose storage as glycogen.

Pregnancy

GLZ Plus Tablet use during pregnancy needs caution. It's best to consult your doctor before taking this medicine if you are pregnant or planning to conceive.

Breastfeeding

Breastfeeding women should exercise caution while taking GLZ Plus Tablet. Always discuss it with your doctor to understand potential risks and benefits.

Alcohol

Drinking alcohol while on medication could increase the risk of low blood sugar (hypoglycemia). Be careful and talk to your doctor about safe alcohol consumption.

Liver

If you have any liver health issues, it's advised to discuss them with your doctor before starting GLZ Plus Tablet, as it may affect liver function.

Kidney

GLZ Plus Tablet use warrants caution if you have a history of kidney health problems. It's a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

GLZ Plus Tablet may cause dizziness or affect alertness, which could impact activities like driving or operating machinery. Be cautious until you know how this medicine affects you.

Allergy

If you have known allergies to gliclazide or metformin, the active ingredients in GLZ Plus Tablet, avoid using it. Always inform your doctor about any allergies before starting this medication.

Children

GLZ Plus Tablet is not recommended for children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take GLZ Plus Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

GLZ Plus Tablet interacts with the following medicines:

Other antidiabetic agents: The glucose-lowering effect of GLZ Plus Tablet can be enhanced when taken with other antidiabetic agents such as insulin or thiazolidinediones.
Diuretics: Diuretics like furosemide or hydrochlorothiazide may reduce the blood sugar control effect of GLZ Plus Tablet.
Corticosteroids: Medicines like prednisolone may increase blood sugar levels, reducing the effectiveness of GLZ Plus Tablet.
Thyroid hormones: Synthetic thyroid hormones like levothyroxine may increase blood glucose levels, affecting the efficacy of this medication.
Estrogens and oral contraceptives: These can increase blood glucose levels, potentially reducing the effectiveness of GLZ Plus Tablet.
Isoniazid: This anti-tuberculosis medicine can increase blood sugar levels, affecting the efficacy of this medication.

Drug-Food Interactions

Certain foods containing high sugar and high fat can interact with GLZ Plus Tablet. It's best to consume this medication with meals to prevent an upset stomach.

Drug-Disease Interactions

GLZ Plus Tablet interacts with the following diseases:

Type 1 diabetes mellitus: This medication is not suitable as it works by improving insulin release and function, which is impaired in type 1 diabetes.
Severe renal impairment: The ingredients in GLZ Plus Tablet may accumulate in the body if kidney function is severely impaired, potentially resulting in toxicity.
Liver disease: Individuals with liver disease could have altered metabolism and excretion, potentially leading to increased concentrations of the medication and side effects.

Daily Dose

The daily dose of GLZ Plus Tablet is to be taken as directed by your doctor, factoring in your health condition and response to therapy. Always stick to the prescribed dosage and do not modify it without consulting your doctor.

Over Dose

If you accidentally take more GLZ Plus Tablets than prescribed, you might experience common symptoms like nausea, stomach upset, or a feeling of general discomfort. Should these symptoms persist, please inform your doctor.

Missed Dose

If you forget to take your GLZ Plus Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your normal schedule. Never increase your dose without consulting your doctor.

Store your GLZ Plus Tablet in a dry place, protected from light and moisture.
The ideal storage temperature should not exceed 25 °C.
Keep the medicine out of the reach and sight of children.
Always check the expiry date on the package before using it.

Follow a balanced diet rich in fibre and low in simple sugars to help manage your blood sugar levels.
Regular physical activity, like walking or yoga, can assist in managing type 2 diabetes by improving insulin sensitivity.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus
Drug Category	Insulin Secretagogue, Biguanide
Therapeutic Category	Antidiabetic

What is the GLZ Plus Tablet used for?

GLZ Plus Tablet is an oral medication used to manage type 2 diabetes mellitus in adults when diet and exercise alone are insufficient.

How does GLZ Plus Tablet work?

GLZ Plus Tablet contains two ingredients, gliclazide and metformin, which work together to reduce high blood sugar levels by increasing insulin production and improving insulin sensitivity.

Are there any side effects of GLZ Plus Tablet?

Common side effects include nausea, vomiting, diarrhoea, abdominal pain, headache, dizziness, and low blood sugar. Contact your doctor if these persist.

Is GLZ Plus Tablet safe for everyone?

No, it's not recommended for people with type 1 diabetes, severe kidney problems, metabolic acidosis or those allergic to gliclazide or metformin.

Can I take other medicines while using GLZ Plus Tablet?

Some Beta-blockers such as metoprolol and antidiabetic medicine may interact with GLZ Plus Tablet. Always consult your doctor before starting any new medication.

How should I store my GLZ Plus Tablets?

Store your tablets at a temperature not exceeding 25 °C, away from light and moisture. Keep out of reach of children and pets.

What lifestyle modifications can complement the use of GLZ Plus Tablet?

Healthy eating habits, regular physical activity, and regular blood glucose monitoring can help manage type 2 diabetes along with taking GLZ Plus Tablet.

Last Updated On 14 Aug. 2025 | 12:30PM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Divya Chauhan

Medical Content Writer & Reviewer | 7 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Alembic Road, Vadodara - 390 003, Gujarat,INDIA

Country of origin: INDIA

Expiry on or after: January 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

NHS Choices. (n.d.). Gliclazide. Retrieved 1 April 2024, from https://www.nhs.uk/medicines/gliclazide/
U.S. National Library of Medicine. (2022). Metformin. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a696005.html
U.S. Food and Drug Administration. (n.d.). FDA Drug Safety Communication: Updated FDA review concludes that use of type 2 diabetes medicine pioglitazone may be linked to an increased risk of bladder cancer. Retrieved 1 April 2024, from https://www.fda.gov/downloads/drugs/drugsafety/ucm280360.pdf

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Intellihealth Solutions Private Limited

Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.

CIN: U62099MH2019PTC320566

Telephone:09240250346

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Email: grievance-officer@truemeds.in

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