Glidapaflozin Trio 1 Forte Tablet 15

Steris Healthcare

Strip of 15 Units

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MRP ~~₹255~~

₹127.24

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Composition

Dapagliflozin (10 Mg) + Glimepiride (1 Mg) + Metformin (1000 Mg)

Glidapaflozin Trio 1 Forte Tablet 15 is used to manage high blood sugar levels in adults with type 2 diabetes mellitus when diet and exercise alone are not enough. It is a combination medicine that belongs to the class of antidiabetic medications.

This medicine helps in controlling blood glucose levels in patients when treatment with a single medicine or dual therapy does not provide adequate control. It works through multiple mechanisms to reduce blood sugar levels effectively, making it suitable for patients who need additional support in managing their diabetes.

Take this medicine orally as directed by your doctor. Before starting, inform your doctor about any pre-existing conditions you may have, especially kidney or liver problems, and any other medicines you are currently taking. If you notice any side effects while using this medicine, notify your doctor promptly. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Glidapaflozin Trio 1 Forte Tablet 15 is used for the following:

Management of type 2 diabetes mellitus in adults
Control of high blood sugar levels
Improvement of glycaemic control
Supplementing diet and exercise for diabetes management
Management of diabetes when single medicines are inadequate
Supporting insulin sensitivity in diabetic patients
Reducing glucose production by the liver
Enhancing glucose elimination through urine
Stimulating natural insulin release from the pancreas

Follow these instructions while taking Glidapaflozin Trio 1 Forte Tablet 15:

Swallow the tablet whole with a glass of water.
Take it in the morning with or without food.
Do not crush, break, or chew the tablet.
Continue taking this medicine regularly as advised by your doctor.
Do not stop taking this medicine without consulting your doctor.

Glidapaflozin Trio 1 Forte Tablet 15 is taken orally.

Glidapaflozin Trio 1 Forte Tablet 15 may have the following side effects:

Female genital infections: These are fungal infections that can cause itching and discomfort in the genital area.
Urinary tract infections
Diarrhoea
Headache
Nausea
Hypoglycaemia: This refers to low blood sugar levels that may cause symptoms like sweating, shakiness, hunger, and confusion.
Nasopharyngitis: This is inflammation of the nasal passages and the back of the throat, commonly known as a cold.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Glidapaflozin Trio 1 Forte Tablet 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Taking this medicine with food can help reduce feelings of sickness.
Hypoglycaemia: Having this medicine with or just after meals can help prevent low blood sugar episodes.

Glidapaflozin Trio 1 Forte Tablet 15 contains three active ingredients that work together to control blood sugar levels:

Dapagliflozin (10 mg): Acts as a selective SGLT2 inhibitor that reduces the reabsorption of filtered glucose in your kidneys and promotes its excretion through urine, thereby lowering blood glucose levels independently of insulin.
Glimepiride (1 mg): Functions as a sulfonylurea that stimulates your pancreas to produce more insulin by binding to receptors on pancreatic beta cells, which causes these cells to release insulin into your bloodstream.
Metformin (1000 mg): This is a biguanide that decreases glucose production in the liver, reduces glucose absorption from the intestines, and improves insulin sensitivity by increasing glucose uptake and use in peripheral tissues.

Pregnancy

Glidapaflozin Trio 1 Forte Tablet 15 is not recommended during the second and third trimesters of pregnancy. The medicine may affect kidney development in the unborn baby. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Glidapaflozin Trio 1 Forte Tablet 15 is contraindicated during breastfeeding. The active ingredients can pass into breast milk and may cause low blood sugar in nursing infants. Consult your doctor about alternative medicines or feeding options during your treatment.

Alcohol

You should avoid alcohol while taking Glidapaflozin Trio 1 Forte Tablet 15. Alcohol may increase the risk of lactic acidosis (a dangerous build-up of acid in your blood) and can affect your blood sugar control. It might also enhance the blood glucose-lowering effect of this medicine.

Liver

Caution is advised while taking Glidapaflozin Trio 1 Forte Tablet 15 if you have liver problems. This medicine is not recommended for patients with liver impairment as it may lower your blood sugar more significantly. Your doctor should evaluate your liver function before prescribing this medicine.

Kidney

Glidapaflozin Trio 1 Forte Tablet 15 is contraindicated if you have severe kidney problems or are on dialysis. The medicine is removed from your body through your kidneys and may accumulate to harmful levels if your kidneys aren't working properly. Your doctor should check your kidney function before and during treatment.

Using Machines & Driving

You should be cautious while driving or operating machinery when taking Glidapaflozin Trio 1 Forte Tablet 15. This medicine may cause low blood sugar (hypoglycaemia), which can affect your concentration and reaction time. Be aware of the warning signs of low blood sugar before driving.

Allergy

Do not take Glidapaflozin Trio 1 Forte Tablet 15 if you are allergic to dapagliflozin, glimepiride, metformin, or any ingredients in the medicine. Tell your doctor about any past allergic reactions to medicines, especially diabetes medications. Seek immediate medical help if you develop a rash, itching, or breathing difficulties.

Children

Caution is advised regarding Glidapaflozin Trio 1 Forte Tablet 15 for children under 18. The safety and effectiveness of this medicine have not been established in children. This medicine is intended only for adults with type 2 diabetes.

Older Patients

Older patients should take Glidapaflozin Trio 1 Forte Tablet 15 under careful medical supervision. You may be more susceptible to side effects like reduced blood volume and kidney problems. Your doctor may need to check your kidney function more frequently, as this medicine is primarily removed by the kidneys.

Drug-Drug Interactions

Glidapaflozin Trio 1 Forte Tablet 15 interacts with the following medicines:

Insulin secretagogues: Medicines like glibenclamide or gliclazide may increase the risk of hypoglycaemia (low blood sugar) when taken with this tablet.
Protein-bound medicines: Highly protein-bound medicines such as salicylates (choline salicylate), sulfonamides (sulfisoxazole), and chloramphenicol can interact with glimepiride in this tablet, affecting blood glucose control.
Carbonic anhydrase inhibitors: Medicines like acetazolamide or topiramate may increase the risk of lactic acidosis when taken with metformin in this tablet.
Cationic medicines: Medicines such as cimetidine, dolutegravir, and vandetanib can reduce metformin clearance, potentially increasing its levels in the blood.

Drug-Disease Interactions

Glidapaflozin Trio 1 Forte Tablet 15 interacts with the following diseases:

Renal impairment: This medicine is contraindicated in severe kidney disease (EGFR below 30 ml/min/1.73 m²) as it may worsen kidney function.
Metabolic acidosis: Patients with this condition should not take this medicine as it may worsen the acidosis.
Liver disease: This medicine should be avoided in patients with liver problems as it may increase the risk of hypoglycaemia and lactic acidosis.
Pancreatitis: There is a risk of worsening inflammation of the pancreas in patients with a history of this condition.

Daily Dose

The daily dose of Glidapaflozin Trio 1 Forte Tablet 15 should be taken as prescribed by your doctor. The dosage may change based on factors such as your response to treatment and kidney function. Follow the prescribed dosage carefully.

Over Dose

An overdose may cause symptoms like excessive sweating, hunger, confusion, rapid heartbeat, and severe low blood sugar (hypoglycaemia). You might also experience nausea, stomach discomfort, and increased urination. Contact your doctor if these occur.

Missed Dose

If you forget to take this medicine, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and resume your regular schedule. Never increase your dosage without consulting your doctor.

Follow these instructions for storing Glidapaflozin Trio 1 Forte Tablet 15:

Store Glidapaflozin Trio 1 Forte Tablet 15 below 30°C in a cool, dry place.
Keep the medicine in its original packaging to protect it from moisture.
Store away from direct sunlight and heat sources.
Always keep medicines out of sight and reach of children.
Check the expiry date before use and discard any expired medicine properly.

Monitor your carbohydrate intake carefully and choose complex carbohydrates (like whole grains and vegetables) over simple sugars to help maintain steady blood glucose levels.
Engage in regular physical activity (at least 150 minutes of moderate exercise weekly), as this improves insulin sensitivity and helps your body use glucose more effectively.

Fact Box

Available Dosage Types	Tablet Er
Habit Forming	No
Ailment	Type 2 diabetes mellitus
Drug Category	SGLT2 inhibitor + sulfonylurea + biguanide
Therapeutic Category	Antidiabetic

What is Glidapaflozin Trio 1 Forte Tablet 15 used for?

It helps manage type 2 diabetes in adults when diet and exercise alone aren't enough. It contains three medicines that work together to lower blood sugar levels.

How does Glidapaflozin Trio 1 Forte Tablet 15 work in the body?

It works through three mechanisms: removing glucose through urine, stimulating insulin release from the pancreas, and reducing glucose production in the liver.

Can I take Glidapaflozin Trio 1 Forte Tablet 15 with food?

Yes, you can take this medicine either with or without food.

What are the common side effects of this medicine?

Common side effects include genital infections, urinary tract infections, headache, nausea, diarrhoea, and sometimes low blood sugar (hypoglycaemia).

Should I avoid alcohol while taking this medicine?

Yes, avoid alcohol as it may increase the risk of lactic acidosis (a rare but serious condition where lactic acid builds up in the blood).

Who should not take Glidapaflozin Trio 1 Forte Tablet 15?

People with severe kidney problems, liver disease, metabolic acidosis, or allergies to any ingredients should not take this medicine.

What should I do if I experience symptoms of low blood sugar?

If you feel dizzy, shaky, hungry, or confused, immediately take sugar or a sweet drink and contact your doctor.

Last Updated On 04 Jun. 2025 | 6:42AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

Tanaji Chowk, Ambedkar Nagar, Kurla West, Kurla, Mumbai, Maharashtra 400070

Country of origin: INDIA

Expiry on or after: December 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

DailyMed. (n.d.). DAPAGLIFLOZIN AND METFORMIN HYDROCHLORIDE- dapagliflozin and metformin hydrochloride tablet, film coated, extended release. Retrieved April 1, 2025, from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=eaf135b6-e378-4f62-a1e7-db45e23668c7
DailyMed. (n.d.). Lookup results. Retrieved April 1, 2025, from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=1200ea71-8a9e-4e49-bb77-7d9fe0d84ae7
National Health Service. (n.d.). How and when to take glimepiride. Retrieved April 1, 2025, from https://www.nhs.uk/medicines/glimepiride/how-and-when-to-take-glimepiride/
U.S. Food and Drug Administration. (2014). FARXIGA (dapagliflozin) tablets, for oral use. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/202293s003lbl.pdf

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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