Empatrol M 12.5/1000 Tablet 10

Q: What is Empatrol M 12.5/1000 Tablet 10 used for?

Empatrol M 12.5/1000 Tablet 10 is used to improve blood sugar control in adults with type 2 diabetes mellitus and to reduce the risk of cardiovascular death in patients with established heart disease.

Q: How does Empatrol M 12.5/1000 Tablet 10 work?

It contains empagliflozin, which removes excess glucose through urine, and metformin which reduces glucose production in the liver.

Q: Can I take Empatrol M 12.5/1000 Tablet 10 during pregnancy?

No, it is not recommended during pregnancy. Always consult your doctor for safer alternatives.

Q: Does Empatrol M 12.5/1000 Tablet 10 cause low blood sugar?

The risk of hypoglycaemia is low when the tablet is taken alone, but the risk increases when combined with insulin or sulfonylureas.

Q: Can elderly patients take Empatrol M 12.5/1000 Tablet 10?

Yes, but with caution, as they are at higher risk of dehydration and kidney problems. Regular monitoring is required.

Aristo Pharmaceuticals Pvt.ltd

Strip of 10 Units

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Old MRP ₹140

MRP ~~₹131.25~~

₹105

₹13.12/Units

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Prescription required for this medicine

Store Below 30^o C

Composition

Empagliflozin (12.5 Mg) + Metformin (1000 Mg)

Empatrol M 12.5/1000 Tablet 10 is prescribed as an adjunct to diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It falls under a class of medications known as antidiabetics.

This tablet, when used in conjunction with a healthy diet and regular exercise, assists in achieving better blood sugar control. Maintaining optimal glycemic levels is vital for preventing or delaying serious health conditions associated with diabetes, such as cardiovascular disease, kidney damage, nerve issues, and vision loss.

Before starting this medication, it's crucial to consult your doctor, who will prescribe the right dosage based on your condition. You should inform your doctor about any pre-existing health conditions or ongoing medications. If you experience any side effects while on this medicine, notify your doctor immediately.

Empatrol M 12.5/1000 Tablet 10 is used for:

Improving glycaemic control in adults with type 2 diabetes mellitus.

Swallow the tablet whole with water.
It can be taken with or without food, preferably in the morning.
Do not chew, crush, or split the tablet.
Always follow your doctor’s instructions regarding timing and dosage.

Empatrol M 12.5/1000 Tablet 10 is taken orally.

Empatrol M 12.5/1000 Tablet 10 may have the following common side effects:

Urinary tract infections
Female genital
Mycotic infections
Diarrhea
Nausea
Flatulence
Abdominal discomfort
Indigestion

Managing the Side Effects:

Most side effects are temporary, generally harmless, and resolve upon discontinuing the use of Empatrol M 12.5/1000 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Urinary tract infections: Drink plenty of water, maintain good personal hygiene, and contact your doctor if you experience burning sensation during urination.
Abdominal discomfort or nausea: Take the medicine with food to reduce discomfort and consult your doctor if pain persists.

Empatrol M 12.5/1000 Tablet 10 contains the following components:

Empagliflozin (12.5 mg): It is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It works by blocking SGLT2 in the kidneys, leading to increased removal of glucose through urine, thereby lowering blood sugar levels.
Metformin (1000 mg): It is a biguanide; metformin helps to reduce the amount of glucose produced by the liver. It also increases the sensitivity of muscle cells to insulin, helping your body use glucose more effectively.

Pregnancy

Empatrol M 12.5/1000 Tablet 10 is not recommended during pregnancy as its safety has not been established. Always consult your doctor before use.

Breastfeeding

Empatrol M 12.5/1000 Tablet 10 is not recommended during breastfeeding as its safety has not been established. Always consult your doctor before use.

Alcohol

Alcohol can affect blood sugar levels and may increase the risk of dehydration or hypoglycaemia when combined with Empatrol M 12.5/1000 Tablet 10. It is best to avoid alcohol during treatment.

Liver

Empatrol M 12.5/1000 Tablet 10 is not recommended in patients with severe liver impairment. Always inform your doctor about any liver-related conditions.

Kidney

Empatrol M 12.5/1000 Tablet 10 is not recommended in patients with moderate to severe kidney impairment (eGFR < 45 mL/min/1.73m²), and contraindicated if eGFR < 30 mL/min/1.73m². Your doctor will assess your kidney function before prescribing this medicine.

Using Machines & Driving

Empatrol M 12.5/1000 Tablet 10 may cause dizziness or drowsiness due to fluctuations in blood sugar. Avoid driving or operating machinery until you know how it affects you.

Allergy

Avoid Empatrol M 12.5/1000 Tablet 10 if you have a known allergy to empagliflozin, metformin or any other ingredient.

Children

Empatrol M 12.5/1000 Tablet 10 is not recommended in patients below 18 years of age.

Older Patients

Older adults, especially those above 70 years, may have increased risk of dehydration, kidney impairment, and hypotension. They should take this medicine strictly under medical supervision.

Drug-Drug Interactions

Empatrol M 12.5/1000 Tablet 10 interacts with the following medicines:

Diuretics: Diuretic medications like furosemide and hydrochlorothiazide could enhance the potential for volume depletion when taken with Empatrol M 12.5/1000 Tablet 10.
Insulin and Insulin Secretagogues: Medicines like insulin or glimepiride that stimulate insulin production may increase the risk of hypoglycaemia when used with Empatrol M 12.5/1000 Tablet 10.
Corticosteroids and Sympathomimetic Agents: Medicines like prednisone, epinephrine, or albuterol may increase blood sugar levels and reduce the effectiveness of Empatrol M 12.5/1000 Tablet 10.

Drug-Disease Interactions

Empatrol M 12.5/1000 Tablet 10 interacts with the following diseases:

Urinary tract infections (UTIs): There may be a higher risk of UTIs while on this tablet.
Vitamin B12 deficiency: The metformin in this tablet can reduce Vitamin B12 levels over time.
Kidney impairment: This tablet should be used with caution; discontinue if kidney function worsens.

Daily Dose

The recommended daily dose of Empatrol M 12.5/1000 Tablet 10 should be taken as per your doctor's advice. It varies depending on factors like the severity of your condition and how you respond to the medicine. Always adhere to the prescribed dosage and never alter it without consulting your doctor.

Over Dose

Taking more than the prescribed dose of Empatrol M 12.5/1000 Tablet 10 may cause severe dehydration, excessive urination, dizziness, or low blood sugar. Seek medical attention immediately.

Missed Dose

If you forget to take a dose of Empatrol M 12.5/1000 Tablet 10, take it as soon as you can. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not alter your dosage without your doctor's advice.

Store in a cool and dry place, away from moisture and direct sunlight.
Keep out of reach of children.
Do not use after the expiry date mentioned on the pack.

Avoid excessive sugary foods and refined carbohydrates.
Stay hydrated to counter risk of dehydration.
Monitor your blood sugar levels regularly and maintain follow-up visits with your doctor.

Fact Box

Available Dosage Types	Tablet Er
Habit Forming	No
Ailment	Type 2 diabetes mellitus, cardiovascular risk reduction in diabetes
Drug Category	SGLT2 inhibitor + biguanide
Therapeutic Category	Antidiabetics

What is Empatrol M 12.5/1000 Tablet 10 used for?

Empatrol M 12.5/1000 Tablet 10 is used to improve blood sugar control in adults with type 2 diabetes mellitus and to reduce the risk of cardiovascular death in patients with established heart disease.

How does Empatrol M 12.5/1000 Tablet 10 work?

It contains empagliflozin, which removes excess glucose through urine, and metformin which reduces glucose production in the liver.

Can I take Empatrol M 12.5/1000 Tablet 10 during pregnancy?

No, it is not recommended during pregnancy. Always consult your doctor for safer alternatives.

Does Empatrol M 12.5/1000 Tablet 10 cause low blood sugar?

The risk of hypoglycaemia is low when the tablet is taken alone, but the risk increases when combined with insulin or sulfonylureas.

Can elderly patients take Empatrol M 12.5/1000 Tablet 10?

Yes, but with caution, as they are at higher risk of dehydration and kidney problems. Regular monitoring is required.

Last Updated On 21 Sep. 2025 | 11:55AM (IST)

Certified Content

Written by

Dr. Divya Mandial

Medical Content Writer | 9 years

PhD in Chemistry

Reviewed by

Dr. Betina Chandolia

Lead Medical Content Reviewer | 10 years

BDS, MDS, PGCCL, PGDMH

Check out Editorial Policy

Manufacturer details

23 A, Shah Industrial Estate, Off Veera Desai Rd, Andheri West, Mumbai, Maharashtra 400053

Country of origin: INDIA

Expiry on or after: March 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

SYNJARDY® (empagliflozin and metformin hydrochloride) tablets, . (N.d.). Fda.Gov. Retrieved August 25, 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/206111lbl.pdf
Boehringer Ingelheim. (2021). Jardiance 10 mg and 25 mg Film-Coated Tablets Summary of Product Characteristics. https://www.ema.europa.eu/en/documents/product-information/jardiance-epar-product-information_en.pdf
Empagliflozin: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a614043.html
Empagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09038

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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