Emeset Injection 2ml

Cipla Ltd.

AMPOULE of 4 ML
AMPOULE of 2 ML

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Composition

Ondansetron (2 Mg)

Emeset Injection is used to prevent and treat severe nausea and vomiting (feeling and being sick) associated with specific medical procedures. It is primarily administered to manage symptoms resulting from cancer chemotherapy, radiation therapy, and post-operative nausea and vomiting (PONV) that occurs after a surgical procedure.

In addition, this injection is also beneficial in preventing nausea and vomiting induced by chemotherapy and radiotherapy. It's particularly effective during the initial and repeat courses of moderate-to-highly emetogenic cancer chemotherapy.

Before you start using this medicine, it's crucial to consult your doctor for the right dosage and frequency. Let your doctor know about any current health conditions or ongoing medications. If you experience any side effects while on this medication, notify your doctor at once. For optimal results, continue with the prescribed course of this medication as directed by your doctor.

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Emeset Injection is a prescription medication used to treat nausea and vomiting caused by chemotherapy, radiation, or surgery. It works by blocking the action of serotonin, a chemical in the body that can trigger nausea and vomiting, thereby providing relief from these symptoms.

Follow these instructions while administering Emeset Injection:

The injection should be administered by a healthcare professional.
The medication is infused intravenously over a period of 15 minutes or more, depending on the dose and indication.
For chemotherapy-induced nausea and vomiting, the first dose is generally given 30 minutes before chemotherapy.
For postoperative nausea and vomiting, the injection is usually administered immediately before anaesthesia induction.

Remember, for specific advice on how to use this medicine, it's best to consult your doctor.

Emeset Injection is administered intravenously.

Some common side effects of Emeset Injection include headache, constipation, a temporary sensation of flushing or warmth, and local pain or redness at the injection site.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Emeset Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Constipation: Increasing your intake of fibrous foods and fluids can help manage this.
Diarrhoea: Keeping yourself well-hydrated by drinking lots of fluids can aid in managing this symptom.

Emeset Injection contains ondansetron (2 mg) which acts on your body in the following ways:

Selective Serotonin Blockage: Ondansetron works by selectively blocking serotonin's action at 5-HT3 receptors. Serotonin is a substance that can cause nausea and vomiting when released in the small intestine due to certain triggers like chemotherapy drugs.
Prevention of Serotonin-Induced Vomiting: By antagonising these receptors, ondansetron stops serotonin from causing feelings of nausea or prompting a vomiting response. This action assists in managing nausea and vomiting effectively.

Pregnancy

Is it safe to use Emeset Injection during pregnancy?

Caution is advised while taking Emeset Injection if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Is it safe to use Emeset Injection during breastfeeding?

There isn't clear information about whether Emeset Injection can pass into breast milk. If you are breastfeeding, discuss it with your doctor before taking this medicine.

Alcohol

Is it safe to drink alcohol while using Emeset Injection?

The interaction of Emeset Injection with alcohol is not known. However, it's generally a good idea to avoid alcohol when on medication, so consult your doctor for more specific advice.

Liver

Is it advisable to use Emeset Injection when experiencing liver problems?

If you have liver issues, please consult with your doctor before starting Emeset Injection. This medicine may affect the function of your liver.

Kidney

Is it advisable to use Emeset Injection when experiencing kidney problems?

Caution is advised before using Emeset Injection if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Is it safe to operate heavy machinery or drive when using Emeset Injection?

Emeset Injection might cause dizziness or drowsiness in some cases. If you experience such symptoms, avoid driving or operating heavy machinery until you feel normal again.

Allergy

Are there any specific conditions that should be considered before using Emeset Injection?

Emeset Injection is contraindicated in patients with known hypersensitivity to ondansetron or any components of the formulation. If you've had an allergic reaction to similar medicines in the past, discuss this with your doctor before starting this medicine.

Children

Is Emeset Injection suitable for infants or children?

Emeset Injection can be safely administered to children above the age of 6 months for managing nausea and vomiting due to chemotherapy, and above the age of 1 month for postoperative settings. Always consult your doctor before giving any medicine to a child.

Older Patients

Is Emeset Injection suitable for older patients?

Older patients should take Emeset Injection under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Emeset Injection interacts with the following medicines:

Apomorphine: Profound low blood pressure and loss of consciousness may occur when Emeset 2 mg is administered with apomorphine.
Serotonergic Drugs: Medicines like fluoxetine or venlafaxine alongside Emeset 2 mg may increase the risk of a condition called serotonin syndrome.
QT-prolonging Drugs: Medicines like amiodarone or haloperidol, when given with Emeset 2 mg, may further prolong the QT interval, a measure of heart rhythm.
CYP3A4 Inducers/Inhibitors: Medicines like rifampicin (a CYP3A4 inducer) may decrease ondansetron plasma concentrations, while ketoconazole (a CYP3A4 inhibitor) may increase them.

Drug-Food Interactions

Emeset Injection has no known specific food interactions. However, it's always wise to follow your doctor's advice on dietary restrictions if any.

Drug-Disease Interactions

Emeset Injection interacts with the following diseases:

Long QT Syndrome: This medicine may prolong the QT interval in a dose-dependent manner. Therefore, it's not advised for patients with congenital Long QT Syndrome.
Serotonin Syndrome: When administered along with other serotonergic drugs, this medicine could potentially trigger serotonin syndrome, so caution is needed.
Gastric Distention: Emeset 2 mg should be used cautiously in postoperative patients and those undergoing chemotherapy as it might mask symptoms of progressive ileus or gastric distention.

Daily Dose

Your doctor will prescribe the correct daily dose of Emeset Injection for you. It's essential to follow this prescribed dosage, taking into account your individual needs and response to treatment. For more detailed information, please consult the package insert.

Over Dose

If you accidentally administer more than the prescribed dose of Emeset Injection, you may experience symptoms such as dizziness and constipation. If these symptoms persist or worsen, don't hesitate to inform your doctor.

Missed Dose

If you realise you've missed a dose of Emeset Injection, administer it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never adjust your dosage without first consulting your doctor.

Store Emeset Injection between 2°C and 30°C, ideally in a cool place.
Keep the medicine well protected from light.
Do not freeze.
Always keep Emeset Injection out of reach of children.
Use the medicine before its expiry date for optimal effectiveness.

If you are undergoing cancer chemotherapy or radiotherapy, maintain a well-balanced, nutritious diet. This helps to manage side effects like nausea and vomiting, which Emeset Injection is administered to prevent.
Stay hydrated. Drinking plenty of fluids can help manage constipation or diarrhoea, potential side effects of this medicine.

Fact Box

Available Dosage Types	Injection
Habit Forming	No
Ailment	Cancer Chemotherapy, Radiotherapy, Postoperative Nausea
Drug Category	5-HT3 Receptor Antagonist
Therapeutic Category	Antiemetic

What is Emeset Injection used for?

Emeset Injection is used to prevent and treat nausea and vomiting caused by medical treatments.

How does Emeset Injection work?

It works by blocking the action of serotonin, a substance that can cause nausea and vomiting, at specific receptors in your body.

How should I administer Emeset Injection?

This medicine is usually administered by injecting into a vein as directed by your doctor.

Who should avoid taking Emeset Injection?

Individuals allergic to ondansetron or any components of the injection, those with long QT syndrome, or taking apomorphine should avoid it.

Can I take Emeset Injection during pregnancy or while breastfeeding?

Consult your doctor before using this medicine if you're pregnant or breastfeeding. Its safety hasn't been fully established.

Are there any side effects associated with Emeset Injection?

Common side effects include headache, constipation, diarrhoea, fever, dizziness, drowsiness, and reactions at the injection site.

How should I store Emeset Injection?

Store it between 2°C and 30°C, protected from light. Don't freeze it. Discard unused portions.

Is Emeset Injection effective for general vomiting or stomach upset?

Emeset Injection is effective in preventing and treating nausea and vomiting related to medical treatments such as chemotherapy, radiotherapy, and surgery, but it is not typically used for general vomiting or mild stomach upset. It works by blocking serotonin receptors that trigger the vomiting reflex in the brain.

Last Updated On 31 Oct. 2025 | 6:59AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Osama Ahmed

Medical Content Writer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

Expiry on or after: March 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

MedlinePlus. (n.d.). Ondansetron Injection. U.S. National Library of Medicine. Retrieved April 1, 2024, from https://medlineplus.gov/druginfo/meds/a606022.html
DailyMed. (n.d.). Ondansetron Injection. National Library of Medicine. Retrieved April 1, 2024, from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=01d69f4d-eddf-4fc8-820b-832f11f2e3c0
U.S. Food and Drug Administration. (2014). Ondansetron. Retrieved April 1, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020007s046lbl.pdf
Colthup, P. V., Felgate, C. C., Palmer, J. L., & Scully, N. L. (1991). Determination of ondansetron in plasma and its pharmacokinetics in the young and elderly. Journal of pharmaceutical sciences, 80(9), 868–871. https://doi.org/10.1002/jps.2600800913
Huybrechts, K. F., Hernandez-Diaz, S., Straub, L., Gray, K. J., Zhu, Y., Mogun, H., & Bateman, B. T. (2020). Intravenous Ondansetron in Pregnancy and Risk of Congenital Malformations. JAMA, 323(4), 372–374. https://doi.org/10.1001/jama.2019.18587

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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