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CompositionAcogut 300 ER Tablet is used to manage functional dyspepsia by improving movement in the gastrointestinal tract. It helps ease upper abdominal discomfort, bloating, early fullness, and post-meal heaviness through its extended-release action.
Before taking the tablet, inform your doctor about any health issues or medicines you use. Mild nausea or headache may appear. Continue the medicine exactly as prescribed to get lasting digestive relief.
Acogut 300 ER Tablet is used to treat functional dyspepsia (indigestion), relieving symptoms such as bloating, upper stomach pain, and early satiety. It works by improving the stomach’s ability to move food more efficiently, reducing discomfort and promoting better digestion.
These are the instructions for taking Lupin's Acogut 300 ER Tablet:
Lupin's Acogut 300 ER Tablet is taken orally.
Acogut 300 ER Tablet may cause side effects such as headache, diarrhea, constipation, nausea, vomiting, and abdominal pain. These effects are generally mild and may subside over time.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Lupin's Acogut 300 ER Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Try taking Lupin's Acogut 300 ER Tablet with food to manage diarrhoea. If you feel discomfort in your belly after taking this medicine, consider having it after meals.
Lupin's Acogut 300 ER Tablet contains acotiamide (300 mg) which acts on the body in the following way:
Enhances acetylcholine release: Acotiamide works by increasing the release of acetylcholine. This neurotransmitter plays a key role in stimulating mobility in your gastrointestinal tract.
Acts as an antagonist at muscarinic receptors: Acotiamide acts as an antagonist at the M1 and M2 muscarinic receptors and enhances acetylcholine release by antagonizing presynaptic muscarinic M4 receptors. This dual action results in improved gastric emptying and reduced symptoms of functional dyspepsia.
Caution is advised while taking Lupin's Acogut 300 ER Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.
If you are breastfeeding, it's important to discuss this with your doctor before starting Lupin's Acogut 300 ER Tablet.
It is advised not to drink alcohol while taking this medication to avoid any kind of adverse effects.
Caution is advised while taking Lupin's Acogut 300 ER Tablet in case of liver health issues. If you have liver problems, discuss them with your doctor before starting this medicine.
Caution is recommended before using Lupin's Acogut 300 ER Tablet if you have a history of kidney problems. It is advisable to consult your doctor before starting this medication.
Lupin's Acogut 300 ER Tablet is unlikely to affect your ability to drive or operate machinery. Always be cautious and consult your doctor if you're unsure.
Lupin's Acogut 300 ER Tablet is not recommended if you have known allergies to acotiamide or any other ingredients in the formulation.
Lupin's Acogut 300 ER Tablet should not be given to children under 18 years of age without medical supervision. Always consult your doctor before giving any medicine to a child.
Older patients should take Lupin's Acogut 300 ER Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.
Lupin's Acogut 300 ER Tablet interacts with the following medicines:
Anticholinergic Agents: These medications, such as hyoscine or atropine, can reduce the effectiveness of acotiamide in Lupin's Acogut 300 ER Tablet, as they also affect neurotransmitter release.
Dopamine Agonists: Medicines like bromocriptine or pramipexole may enhance the effects on gastrointestinal motility when taken with Lupin's Acogut 300 ER Tablet, due to their additive action.
Other prokinetic agents: Other prokinetics like metoclopramide may be metabolised through the same pathway as acotiamide, which may change the way Lupin's Acogut 300 ER Tablet is metabolised.
There are no known specific food interactions with Lupin's Acogut 300 ER Tablet.
Lupin's Acogut 300 ER Tablet interacts with the following diseases:
Severe Hepatic Impairment: Those with severe liver disease should be careful when using this medicine, as it may worsen their condition.
Severe Renal Impairment: Patients with severe kidney disease should use caution, as the medicine may exacerbate their condition.
Your daily dose of Lupin's Acogut 300 ER Tablet should be as advised by your doctor, taking into account your individual health condition and response to the medicine. Always stick to the prescribed dosage and avoid exceeding it without a doctor's consultation. For detailed information, you can refer to the package insert.
Overdosing on Lupin's Acogut 300 ER Tablet might lead to an intensification of common side effects such as diarrhoea, stomach cramps, or vomiting. In such instances, supportive care including fluid and electrolyte management could be beneficial. If symptoms persist, seek medical attention.
If you forget to take Lupin's Acogut 300 ER Tablet at the scheduled time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.
Store Lupin's Acogut 300 ER Tablet at a room temperature not exceeding 30°C.
Keep it away from moisture and direct sunlight.
Always keep the tablet in its original packaging until you're ready to take it.
Remember, this medicine should be kept out of reach of children.
Ensure to use the tablet before its expiry date.
Since Lupin's Acogut 300 ER Tablet is used to manage functional dyspepsia, try eating smaller, more frequent meals instead of three large ones.
Avoid foods that trigger your symptoms; these could include fatty, spicy or acidic foods. This will help manage symptoms and complement the effect of the medication.
| Available Dosage Types | Extended Release Tablet |
| Habit Forming | No |
| Ailment | Functional Dyspepsia, Gastric Emptying Disorders |
| Drug Category | Prokinetic Agent |
| Therapeutic Category | Gastrointestinal Disorder Medicine |
Lupin's Acogut 300 ER Tablet is used to manage functional dyspepsia, a condition causing upper abdominal discomfort, bloating, and early feeling of fullness.
It works by enhancing acetylcholine release, a brain chemical that stimulates stomach movement, thus improving symptoms of functional dyspepsia.
Take the tablet orally as directed by your doctor. Swallow it whole with water; do not crush or chew it.
Common side effects include headache, diarrhoea, constipation, nausea, vomiting, and abdominal pain. If these persist or worsen, consult your doctor.
Certain medicines may interact with this medication. Always inform your doctor about all medications you're taking before starting this tablet.
Pregnant and breastfeeding women should consult their doctor before using this medication due to potential risks.
Store at room temperature not exceeding 30°C, protect from moisture and keep out of reach of children.
Check out Editorial Policy
Kumar, A., Dang, S., Gupta, M., & Anand, V. P. (2021). Efficacy and safety of Acotiamide in the treatment of functional dyspepsia: A multicenter, randomized, controlled trial. Journal of Gastroenterology and Hepatology, 36(2), 321-327. doi: 10.1111/jgh.15043. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765587/ on 1 April 2024.
Siddiqui, M. A., & Ahmad, S. (2021). Acotiamide: a novel prokinetic agent for the management of functional dyspepsia. Gastroenterology Report, 9(2), 89-96. doi: 10.1093/gastro/goaa079. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8098008/ on 1 April 2024.
Matsueda, K., Hongo, M., Tack, J., Saito, Y., & Kato, H. (2015). Clinical trial: dose-dependent therapeutic efficacy of acotiamide hydrochloride (Z-338) in patients with functional dyspepsia 100 mg t.i.d. is an optimal dosage. Neurogastroenterology & Motility, 22(6), 618-e173. doi: 10.1111/j.1365-2982.2010.01488.x. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146483/ on 1 April 2024.
U.S. Food and Drug Administration. (2024). Acotiamide. Retrieved from https://precision.fda.gov/uniisearch/srs/unii/D42OWK5383 on 1 April 2024.
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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