Acotiamide
Uses of Acotiamide
- Acotiamide is a gastroprokinetic medicine used to manage functional dyspepsia, a chronic disorder affecting digestion and movement in the upper digestive tract.
- Acotiamide is commonly used for:
- • Functional dyspepsia: Relieves persistent symptoms such as bloating after meals, upper abdominal discomfort, and early fullness when there is no identifiable structural cause on investigation.
• Postprandial fullness: Eases the uncomfortable feeling of fullness that occurs soon after eating, even after small meals.
• Early satiety: Helps reduce the sensation of feeling full too quickly during a meal, allowing for more comfortable eating.
• Upper abdominal bloating: Relieves bloating and distension localised to the upper abdomen following meals.
Side effects of Acotiamide
Constipation
Diarrhoea
Dry mouth
Headache
How Acotiamide works
- Acotiamide works by improving the coordination and movement of the stomach muscles, helping food pass through the upper digestive tract more efficiently.
- It is classified as a gastrointestinal prokinetic agent. Acotiamide works by inhibiting an enzyme called acetylcholinesterase, which normally breaks down a chemical messenger called acetylcholine in the nerves supplying the stomach
- Acetylcholine is the key signal that stimulates stomach muscle contractions. By blocking its breakdown, Acotiamide increases the availability of acetylcholine at nerve endings in the stomach wall, enhancing stomach muscle contractions and improving gastric motility.
- This improved movement helps food pass more quickly and efficiently from the stomach into the small intestine, reducing the bloating, fullness, and discomfort that occur when stomach emptying is delayed, as commonly seen in functional dyspepsia.
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Expert Advice
Dosage Forms Available
It is available as an oral tablet.
Age And Dose Restrictions
This medicine is meant for adults.
Contradictions
This medication should not be used if you have an allergy or hypersensitivity to acotiamide, or any blockage or bleeding in your gastrointestinal tract.
Other Medications to Avoid
This medication may interact with anticholinergic agents (e.g., dicyclomine, propantheline) and opioid medicines that delay the emptying of the stomach (e.g., like morphine and codeine).
Overdose and Missed Dose
- If you think you have taken too much Acotiamide, seek medical help immediately. Signs of an overdose may include constipation, diarrhoea, dry mouth, and headache.
If you forget to take a dose, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue treatment as directed by your doctor. Do not take a double dose to make up for a missed one.
Management of Side Effects
Most people do not experience any side effects when taking this medication. If they do occur, they're usually mild and go away on their own as your body adjusts to the medication. However, if you experience persistent side effects or worsening symptoms, inform your doctor.
Taking this medicine with food can alleviate gastrointestinal issues, and increasing water and fibre intake helps manage constipation.
Taking the medicine with a full glass of water and increasing your water intake after taking the medicine can help reduce dry mouth.
Use in Driving and Operating Machinery
This medication may cause dizziness in some people. If this happens, do not drive or operate heavy machinery until you feel better.
Use In Pregnancy And Lactation
If you are pregnant or breastfeeding, consult your doctor before starting this medication.
Caution In Other Conditions
Acotiamide should be used with caution in patients with liver or kidney disease, as these conditions can affect how the medicine is processed in the body. If you have any of these conditions, inform your doctor before starting this medication.
Special Dietary And Lifestyle Recommendation
Eating smaller, more frequent meals instead of large meals can help manage your condition.
Avoid the specific foods and drinks that trigger your symptoms.
Regular physical activity like walking or swimming can also help to reduce functional indigestion.
Frequently asked questions
Can Acotiamide cause weight gain?
There is no evidence to suggest that this medicine causes weight gain. If you notice any unusual changes in your weight, consult your doctor.
Does Acotiamide cause drowsiness?
Drowsiness is not a reported side effect of this medicine. However, every person reacts differently to medication. If you feel drowsy after taking it, inform your doctor.
How long does it take for Acotiamide to start working?
You may start noticing an improvement in your symptoms within 2 to 4 weeks of starting this medicine. However, continue taking the medication as prescribed by your doctor, even if your symptoms improve earlier.
Can I drink alcohol while taking Acotiamide?
It is generally recommended to avoid alcohol while taking any medication, as it can increase the risk of side effects.
Is Acotiamide a long-term treatment option?
The duration of treatment will be determined by your doctor, depending on your symptoms and response to the medicine. Take the medication for the full duration recommended by your doctor.
Does Acotiamide interact with other medications?
Yes, this medicine can interact with certain medications. Inform your doctor of all the medications you are currently taking before starting this medicine.
Is Acotiamide an antibiotic medication?
No, it is not an antibiotic. It belongs to the class of medicines called gastroprokinetics.
What is Acotiamide used for?
Acotiamide is used to treat indigestion and stomach discomfort (functional dyspepsia). It helps the stomach empty food faster and improves digestion, reducing bloating and the feeling of fullness after eating.
List of medicines for Acotiamide
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