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CompositionAbvida-M 50/500 Tablet is used to manage type 2 diabetes. It combines vildagliptin and metformin to help control blood sugar. This combination is beneficial when diet and exercise alone aren’t enough.
Take this medicine as prescribed and consult your doctor about any existing health conditions or medications. Report any side effects immediately for optimal results.
Abvida-M 50/500 Tablet is used to manage type 2 diabetes in adults when diet and exercise alone are insufficient. It is used as an additional tool to improve blood sugar regulation and is prescribed when lifestyle changes alone do not provide adequate glycaemic control.
Follow these instructions while taking Abvida-M 50/500 Tablet:
Swallow the tablet whole with a glass of water during meals.
Refrain from crushing or chewing the tablet.
Do not exceed the recommended dose without consulting your doctor.
Consult your doctor before you decide to stop taking this medicine.
Abvida-M 50/500 Tablet is taken orally.
Abvida-M 50/500 Tablet may cause side effects such as gastrointestinal symptoms (diarrhoea, vomiting, abdominal pain, loss of appetite), headache, tremor, dizziness, and nasopharyngitis (inflammation of the nasal passages and throat). If these side effects persist or worsen, consult your doctor.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Abvida-M 50/500 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Gastrointestinal symptoms: Try taking Abvida-M 50/500 Tablet with meals to lessen these effects.
Dizziness: Consider taking this medicine at night if it causes you dizziness during the day.
Abvida-M 50/500 Tablet contains two active ingredients:
Vildagliptin (50 mg): This is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by boosting the levels of incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones stimulate insulin secretion from your pancreas when glucose levels are high and suppress glucagon secretion, thereby reducing blood sugar levels.
Metformin (500 mg): This component helps manage blood sugar levels by reducing the production of glucose in your liver, decreasing the absorption of glucose in your gut, and enhancing insulin sensitivity which leads to an increase in glucose uptake and utilisation by your body's cells. It does not stimulate insulin secretion, so it doesn't cause low blood sugar or hypoglycemia.
Abvida-M 50/500 Tablet is not recommended during pregnancy. If you are pregnant or plan to conceive, ensure your doctor is aware before you start using this medicine.
The use of Abvida-M 50/500 Tablet while breastfeeding is not advised. Your doctor can provide more information on potential risks and benefits.
Avoid alcohol consumption while taking Abvida-M 50/500 Tablet as it can increase the risk of lactic acidosis, a serious metabolic complication.
If you have liver problems, be sure to discuss them with your doctor before starting Abvida-M 50/500 Tablet. This medicine is not recommended for those with hepatic impairment.
Abvida-M 50/500 Tablet is contraindicated in cases of severe renal impairment. It is best to consult your doctor before taking this medicine if you have any history of kidney problems.
No specific caution has been mentioned about using heavy machinery or driving while taking Abvida-M 50/500 Tablet. However, dizziness is a common side effect, so be aware of how this medicine affects you before undertaking such tasks.
If you have known allergies to vildagliptin, metformin, or any other ingredients in Abvida-M 50/500 Tablet, do not take this medication. Always communicate any known allergies with your doctor before starting a new medicine.
Abvida-M 50/500 Tablet is meant for adult use. It should not be given to children under the age of 18 years without medical consultation.
Older patients should take Abvida-M 50/500 Tablet under medical supervision as they may be more susceptible to its side effects. If you are above 70 years of age, your doctor will guide you based on your health status.
Abvida-M 50/500 Tablet interacts with the following medicines:
Cationic medicines: Medicines like amiloride, digoxin, and morphine, which are eliminated by renal tubular secretion, may interact with metformin in this medication. This can lead to increased serum concentrations of both the cationic medicine and metformin.
Other antidiabetic agents: If you're taking other antidiabetic agents like glipizide, glyburide, gliclazide, glimepiride or insulin alongside Abvida-M 50/500 Tablet, you may need a lower dose of these medicines to reduce the risk of hypoglycemia.
Abvida-M 50/500 Tablet interacts with the following diseases:
Renal Impairment: If you have severe renal impairment (eGFR < 30 mL/min/1.73m²), it's not recommended to take this medication as it may worsen your condition.
Hepatic Impairment: Liver function should be assessed before starting treatment as Abvida-M 50/500 Tablet is not recommended for patients with hepatic impairment.
The daily dose of Abvida-M 50/500 Tablet should be taken as recommended by your doctor. Your dosage may vary depending on individual factors like your condition's severity and response to the medication. Always follow your doctor's prescribed dosage and never exceed it without consulting your doctor.
If you accidentally take more than the prescribed dose of Abvida-M 50/500 Tablet, you might experience symptoms like diarrhoea, nausea, and dizziness. In such cases, inform your doctor promptly.
If you forget to take your regular dose of Abvida-M 50/500 Tablet, take it as soon as you recall. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Never adjust your dosage without consulting your doctor.
Store Abvida-M 50/500 Tablet at room temperature, ideally between 15-30°C.
Keep the medicine in a dry place, away from direct sunlight and moisture.
Make sure it is stored out of reach of children.
Remember to use the medication before its expiry date.
Since Abvida-M 50/500 Tablet is used to manage diabetes, you should aim to maintain a balanced diet. Focus on including whole grains, fruits, and vegetables while limiting your intake of sugary foods and drinks.
Regular exercise is pivotal for managing blood sugar levels. Try to include at least 30 minutes of moderate-intensity activity in your daily routine, such as brisk walking or cycling. Always consult your doctor before starting any new exercise regimen.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Type 2 Diabetes Mellitus |
| Drug Category | DPP-4 Inhibitor, Biguanide |
| Therapeutic Category | Antidiabetic |
Yes, it can be used only if your doctor prescribes you. Always consult your doctor before starting any new medication.
Take it as soon as you remember, but skip it if it's nearly time for the next dose. Don't double up.
No, it doesn't cause weight gain. Metformin can sometimes lead to modest weight loss.
This medicine isn't recommended during pregnancy. If you're planning a pregnancy or become pregnant, consult your doctor immediately.
The time varies from person to person. Some people see improvements in a few days, while others may take a few weeks.
It's best to avoid alcohol as it increases the risk of lactic acidosis, a rare but serious side effect of metformin.
Your doctor would prescribe you other medication if you need it. Always consult your doctor first before starting any new medication.
Check out Editorial Policy
MedlinePlus. (n.d.). Metformin. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a696005.html
Sridhar, G. R., Pandit, K., Warrier, S., & Birla, A. (Year of publication). (n.d.). Sustained-release vildagliptin 100 mg in type 2 diabetes mellitus: A review. National Center for Biotechnology Information. Retrieved 1 April 2024, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291938/
Ahrén, B., Foley, J. E., & Bosi, E. (2011). Clinical evidence and mechanistic basis for vildagliptin's action when added to metformin. Diabetes, obesity & metabolism, 13(3), 193–203. https://doi.org/10.1111/j.1463-1326.2010.01321.x
Guarino, E., Nigi, L., Patti, A., Fondelli, C., & Dotta, F. (2012). Combination therapy with metformin plus vildagliptin in type 2 diabetes mellitus. Expert opinion on pharmacotherapy, 13(9), 1377–1384. https://doi.org/10.1517/14656566.2012.667078
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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