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CompositionSynaptol 150 Tablet is used to manage muscle spasms and stiffness associated with neurological conditions such as stroke, Parkinson’s disease, and spinal cord injuries. It works on the central nervous system to reduce muscle pain and "loosen" stiff limbs. This helps patients regain mobility and perform daily activities with greater ease and less discomfort.
Synaptol 150 Tablet is used to assist in stroke rehabilitation and the management of muscle stiffness related to spinal cord injuries or multiple sclerosis. It works by relaxing the skeletal muscles to reduce spasticity and pain, which significantly improves physical mobility and comfort. This makes it easier for patients with neurological conditions to participate in physical therapy and daily activities.
Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Always take this medicine as per your doctor's advice.
Stopping the medicine suddenly is not recommended, especially if you have been using it long-term. Consult your doctor before discontinuing.
Synaptol 150 Tablet is taken orally.
Synaptol 150 Tablet may cause side effects like drowsiness, dizziness, fatigue, dry mouth, nausea, vomiting, abdominal pain, hypotension (low blood pressure), and muscle weakness.
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of the Synaptol 150 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Drowsiness: If Synaptol 150 Tablet makes you feel sleepy during the day, consider taking it at night.
Nausea, vomiting, and abdominal pain: Try taking this medicine with or after meals to lessen these effects.
Synaptol 150 Tablet consists of tolperisone (150 mg), which works as follows:
Blocks Sodium and Calcium Channels: Tolperisone operates centrally, blocking voltage-gated sodium and calcium channels present in your brain stem and spinal cord. This action helps to suppress certain reflexes, reducing muscle stiffness and painful spasms.
Induces Vasodilation: The medicine triggers dilation of blood vessels, specifically in skeletal muscles, thus increasing blood flow to these areas. This effect is selective, with minimal impact on other parts of your body, which helps relax stiff muscles.
Preserve Muscle Strength: Despite its relaxing effect on muscles, tolperisone does not decrease overall muscle strength. In this way, it manages to provide relief from spasms without impacting your mobility or physical function.
Caution is advised while taking Synaptol 150 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.
Caution is advised during breastfeeding before taking this tablet as it may not be safe.
You should avoid consuming alcohol while on a course of Synaptol 150 Tablet since it may have additive effects on the central nervous system and could increase drowsiness and dizziness.
If you have liver health issues, it's important to consult your doctor before starting Synaptol 150 Tablet, especially if you have severe liver impairment.
For those with any kidney problems, caution is advised before using Synaptol 150 Tablet. It is a good idea to consult your doctor before taking this medicine.
Be careful when driving or operating heavy machinery until you know how Synaptol 150 Tablet affects you. This medicine may cause drowsiness or dizziness.
Synaptol 150 Tablet should not be used if you are allergic to tolperisone or any other ingredient of this medicine.
Synaptol 150 Tablet should not be given to children under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older patients should take Synaptol 150 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.
Synaptol 150 Tablet interacts with the following medications:
Benzodiazepines: When taken together with Synaptol 150 Tablet, medications like diazepam and lorazepam can amplify the sedative effects, potentially causing excessive drowsiness.
Opioids: Medicines such as morphine or codeine may increase the central nervous system (CNS) depressant effects when used alongside Synaptol 150 Tablet.
There are no specific known interactions of Synaptol 150 Tablet with any food items.
Synaptol 150 Tablet interacts with the following diseases:
Myasthenia Gravis: This medicine may exacerbate muscle weakness in patients with this condition.
Severe Hepatic or Renal Impairment: Due to potential changes in medicine clearance, a dose adjustment of Synaptol 150 Tablet might be required in patients with severe liver or kidney disease.
Respiratory Depression: As Synaptol 150 Tablet has CNS depressant effects, it could further decrease respiratory drive in individuals with pre-existing respiratory depression.
Your daily dose of Synaptol 150 Tablet should be as directed by your doctor, who will consider factors such as your personal health status and how well you respond to the medicine. It's essential not to exceed this dosage without your doctor's advice. For further details regarding dosage, read the package insert.
If you accidentally take more than the prescribed dose of Synaptol 150 Tablet, you might experience symptoms like excessive drowsiness or confusion. In such cases, inform your doctor about the situation.
Missed a dose of Synaptol 150 Tablet? Don't worry. Take it as soon as you remember. However, if it's nearly time for your next dose, omit the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.
Store your Synaptol 150 Tablet at room temperature.
Shield it from direct sunlight and keep away from damp areas.
Ensure the tablets are not exposed to excessive light or air.
Always keep this medicine out of reach of children.
Use this medication before its expiry date for the best effect.
If you're managing conditions like stroke rehabilitation or spinal cord injuries with Synaptol 150 Tablet, consider engaging in regular gentle exercises suitable for your condition, as recommended by your doctor. This helps improve mobility and lessen muscle stiffness.
Adopt a balanced diet rich in antioxidants (found in fruits and vegetables) which aid recovery by combating inflammation caused by neurological disorders such as multiple sclerosis and Parkinson's disease.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Spinal Cord Injuries, Stroke Rehabilitation, Multiple Sclerosis |
| Drug Category | Voltage-Gated Channel Blocker |
| Therapeutic Category | Muscle Relaxant |
It's used to manage painful muscle spasms and stiffness linked to neurological disorders like stroke, spinal cord injuries, and Parkinson's disease.
It contains tolperisone that blocks certain channels in the brain and spinal cord, reducing muscle stiffness and spasms without weakening muscle strength.
Yes, common side effects can include drowsiness, fatigue, and dizziness. Avoid driving or operating heavy machinery until you know how it affects you.
This medicine should be used during pregnancy only if benefits outweigh risks. Always consult your doctor before taking any medication during pregnancy.
Yes, it can have added effects when used with certain medicines like benzodiazepines and opioids. Always inform your doctor about all medications you're taking
Overdose may cause excessive drowsiness, confusion, and other serious symptoms. If you suspect an overdose, seek immediate medical attention.
Store them at room temperature in a cool, dry place protected from light and moisture. Keep them out of reach of children.
Check out Editorial Policy
Tolperisone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06264
Tolperisone - referral | European Medicines Agency. (n.d.). https://www.ema.europa.eu/en/medicines/human/referrals/tolperisone
Quasthoff, S., Möckel, C., Zieglgänsberger, W., & Schreibmayer, W. (2008). Tolperisone: A Typical Representative of a Class of Centrally Acting Muscle Relaxants with Less Sedative Side Effects. CNS Neuroscience & Therapeutics, 14(2), 107–119. https://doi.org/10.1111/j.1527-3458.2008.00044.x
Tekes, K. (2014). Basic aspects of the pharmacodynamics of Tolperisone, a widely applicable centrally acting muscle relaxant. the Open Medicinal Chemistry Journal, 8(1), 17–22. https://doi.org/10.2174/1874104501408010017
Nalamachu, S., Pergolizzi, J., & Kaye, R. (2020). Tolperisone for the Treatment of Acute Muscle Spasm of the Back: Results from the Dose-Ranging Phase 2 STAR Study (NCT03802565) Journal of Pain Research, Volume 13, 3059–3069. https://doi.org/10.2147/jpr.s278857
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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