Sulfunol 500 Tablet 15 is used in adults for the treatment and long-term management of inflammatory conditions such as ulcerative colitis, Crohn’s disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and juvenile idiopathic arthritis. It belongs to the class of medicines known as anti-inflammatory and disease-modifying agents.
It is also prescribed for the prevention of relapses in ulcerative colitis, helping patients maintain remission between flare-ups. This medicine is not suitable for the immediate relief of acute symptoms and must be taken regularly as directed by your doctor.
Before starting Sulfunol 500 Tablet 15, it is important to consult your doctor. The dosage and treatment duration will depend on your condition, age, weight, liver and kidney function, and treatment response. Any unusual or severe side effects should be promptly reported.
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Sulfunol 500 Tablet 15
Strip of 15 Units
Old MRP ₹70.72
MRP ₹66.3
₹48.37
₹4.42/Units
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CompositionAbout Sulfunol 500 Tablet 15
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Uses of Sulfunol 500 Tablet 15
Sulfunol 500 Tablet 15 is used for:
- Treatment of mild to moderate ulcerative colitis.
- Adjunctive therapy in severe ulcerative colitis.
- Maintenance of remission in ulcerative colitis.
- Management of Crohn’s disease.
- Relief of symptoms in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis.
- Treatment of juvenile idiopathic arthritis (in selected cases).
Directions for Use of Sulfunol 500 Tablet 15
- Swallow the tablets whole with water, preferably after meals to reduce stomach irritation.
- Do not crush or chew the tablets.
- Drink sufficient fluids throughout the day while taking this medicine.
- Follow your doctor’s prescription carefully and do not alter the dose on your own.
Route of Administration
Sulfunol 500 Tablet 15 is for oral use only.
Side Effects of Sulfunol 500 Tablet 15
#sku_name# may cause the following common side effects:
- Headache
- Indigestion
- Nausea and vomiting
- Changes in taste
- Abdominal discomfort
- Skin rash
Managing the Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Sulfunol 500 Tablet 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
- Headache: Rest in a quiet environment and stay well hydrated.
- Nausea/indigestion: Take the medicine after meals and avoid spicy, fatty foods.
How Sulfunol 500 Tablet 15 Works?
Sulfunol 500 Tablet 15 contains the following active component:
- Sulfasalazine (500 mg): It reduces inflammation by inhibiting the production of prostaglandins, chemicals responsible for pain and swelling. Its breakdown products, sulphapyridine and 5-aminosalicylic acid, provide both antibacterial and anti-inflammatory effects in the intestines and joints.
Safety Measures & Warnings
Pregnancy
Sulfunol 500 Tablet 15 should only be used during pregnancy if clearly advised by your doctor. High doses may reduce folate absorption, which is important for foetal development. Supplementation may be required.
Breastfeeding
Sulfasalazine passes into breast milk. Use during breastfeeding is not generally recommended, as it may cause diarrhoea or blood-related issues in the infant. Consult your doctor before use.
Alcohol
Alcohol can irritate the stomach and worsen gastrointestinal side effects such as nausea or indigestion caused by Sulfunol 500 Tablet 15. Limiting or avoiding alcohol is advisable during treatment.
Liver
Patients with liver disease must exercise caution, as Sulfunol 500 Tablet 15 can increase liver enzyme levels. Regular monitoring of liver function tests is necessary.
Kidney
As Sulfunol 500 Tablet 15 may affect kidney function and increase the risk of kidney stones, it should be used with caution in patients with kidney disease. Adequate hydration is strongly advised.
Using Machines & Driving
Sulfunol 500 Tablet 15 generally does not impair alertness. However, if you feel dizzy or unwell, avoid driving, cycling, or operating heavy machinery.
Allergy
Do not take Sulfunol 500 Tablet 15 if you are allergic to sulfasalazine, sulphonamides, salicylates, or any component of the tablet. Severe allergic reactions such as rash, swelling, or breathing difficulty require immediate medical attention.
Children
Sulfunol 500 Tablet 15 can be used in children above 6 years of age when prescribed.
Older Patients
Older patients may be more prone to blood disorders, kidney impairment, or liver issues while on Sulfunol 500 Tablet 15. Closer monitoring is required in this age group.
Sulfunol 500 Tablet 15 interacts with the following medicines:
- Blood thinners (warfarin): The concomitant use may increase the risk of bleeding.
- Digoxin (heart medicine): The concomitant use may reduce absorption and effectiveness.
- Iron and folic acid supplements: The concomitant use may reduce absorption; supplementation may be required.
- Antidiabetic medicines (glimepiride, glyburide, glipizide): The concomitant use may enhance hypoglycaemic effect.
- Methotrexate (arthritis/cancer treatment): The concomitant use may increase risk of toxicity.
- Azathioprine and mercaptopurine (immune-suppressing agents): The concomitant use may increase risk of bone marrow suppression.
- Isoniazid (anti-tuberculosis medicine): The concomitant use may increase risk of liver damage.
- Methenamine (antibiotic): The concomitant use may reduce effectiveness of this medicine.
Interactions of Sulfunol 500 Tablet 15
Drug-Food Interactions
Sulfunol 500 Tablet 15 should be used with caution in patients with:
- Intestinal or urinary obstruction: Sulfunol 500 Tablet 15 may worsen blockages, leading to increased abdominal pain, swelling, or difficulty in urination.
- Porphyria: Sulfunol 500 Tablet 15 can trigger or aggravate an acute porphyria attack due to its sulphonamide component.
- Blood disorders: Sulfunol 500 Tablet 15 may reduce blood cell counts, increasing the risk of anaemia, infections, or unusual bleeding.
Dosage of Sulfunol 500 Tablet 15
Daily Dose
The recommended dose of Sulfunol 500 Tablet 15 varies depending on the condition being treated and your individual response. Your doctor will decide the appropriate dosage for you.
Over Dose
An overdose may cause headache, dizziness, stomach upset, nausea, or vomiting. In severe cases, yellowing of the skin, blood disorders, or kidney problems may occur. If overdose is suspected, seek medical attention immediately.
Missed Dose
If you forget to take a dose, take it as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed dose. Do not double the dose to make up for the forgotten one.
Storage
- Store at room temperature in a dry place.
- Keep the tablets in their original blister pack to protect from moisture.
- Keep out of reach and sight of children.
- Do not use after the expiry date printed on the packaging.
Diet & Lifestyle
- Drink plenty of water: To reduce the risk of kidney stones.
- Low-fibre diet: Choose white rice, bread, pasta, eggs, fish, and tofu during flare-ups.
- Exercise regularly: To reduce inflammation and maintain joint flexibility.
Fact Box
| Available Dosage Types | Tablet Dr |
| Habit Forming | No |
| Ailment | Ulcerative colitis, Crohn’s disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, juvenile idiopathic arthritis |
| Drug Category | Anti-inflammatory and disease-modifying agent |
| Therapeutic Category | Gastrointestinal and rheumatology medicine |
Frequently Asked Questions (FAQs)
What is Sulfunol 500 Tablet 15 used for?
Does Sulfunol 500 Tablet 15 cure ulcerative colitis?
Can I take Sulfunol 500 Tablet 15 during pregnancy?
Can I take Sulfunol 500 Tablet 15 while breastfeeding?
Does Sulfunol 500 Tablet 15 affect driving?
How long do I need to take Sulfunol 500 Tablet 15?
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Manufacturer details
Country of origin: INDIA
References
- Azulfidine® sulfasalazine tablets. (N.d.). Fda.Gov. Retrieved September 17, 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/007073s124lbl.pdf
- Sulfasalazine. (n.d.). Medline Plus. Retrieved August 12, 2023, from https://medlineplus.gov/druginfo/meds/a682204.html
- Highlights Of Prescribing Information For Sulfasalazine. (n.d.). U.S. Food And Drug Administration. Retrieved August 12, 2023, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/007073s124lbl.pdf
- Sulfasalazine. (n.d.). Drugs.Com. Retrieved September 17, 2025, from https://www.drugs.com/sulfasalazine.html
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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