Plectide Tablet 10

Msn Laboratories Ltd

Strip of 10 Units

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MRP ~~₹590~~

₹472

₹59/Units

20% off

*MRP inclusive of all taxes

100% genuine medicines

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15 days Easy returns

Prescription required for this medicine

Store Below 25°C

Composition

Plecanatide (3 Mg)

Plectide Tablet 10 is used to manage chronic idiopathic constipation in adults. It belongs to the class of medicines known as guanylate cyclase-C (GC-C) agonists.

This medicine is commonly prescribed in adults with long-standing constipation associated with infrequent bowel movements, hard stools, straining during bowel movements, abdominal discomfort, bloating, and incomplete bowel evacuation, where the exact cause of constipation is not known. It may help improve bowel movement frequency, soften stools, and support easier passage of stools.

Take this medicine exactly as prescribed by your doctor. Inform your doctor if you have severe diarrhoea, bowel obstruction, dehydration, stomach disorders, liver disease, or kidney disease before starting treatment. This medicine should not be used in children and adolescents below 18 years of age as it may cause serious dehydration.

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Plectide Tablet 10 is used to:

Manage chronic idiopathic constipation in adults
Improve bowel movement frequency
Help soften stools and reduce straining during bowel movements
Support easier stool passage in chronic constipation
Reduce symptoms associated with incomplete bowel evacuation

Follow these instructions while taking Plectide Tablet 10:

Take the tablet exactly as prescribed by your doctor.
Swallow the tablet whole with water.
Do not crush or chew the tablet.
It may be taken with or without food.
Continue taking the medicine regularly for the duration advised by your doctor.

Plectide Tablet 10 is taken orally.

Plectide Tablet 10 may cause side effects such as:

Diarrhoea
Abdominal bloating
Flatulence
Nausea
Upper respiratory tract infection

Management Of Side Effects:

Most side effects are temporary and generally improve as your body adjusts to the medicine. However, if you experience any serious side effects or worsening of any symptoms, consult your doctor.

Here are a few tips that may help:

Diarrhoea: Drink adequate fluids and, if needed, oral rehydration solutions to help prevent dehydration associated with loose stools.
Abdominal bloating: Eating smaller meals and avoiding carbonated drinks may help reduce abdominal bloating during treatment.

Plectide Tablet 10 contains the following active ingredient:

Plecanatide (3 mg): It works locally in the intestines by activating guanylate cyclase-C receptors on the intestinal lining. This increases secretion of chloride and bicarbonate into the intestinal lumen, which helps increase intestinal fluid and improve stool movement through the bowel.

Pregnancy

Plectide Tablet 10 should be used during pregnancy only if advised by your doctor.

Breastfeeding

Consult your doctor before taking Plectide Tablet 10 while breastfeeding. It is not known whether this medicine passes into breast milk.

Alcohol

Avoid excessive alcohol intake while taking this medicine, as alcohol may worsen dehydration associated with diarrhoea.

Liver

Inform your doctor if you have liver disease before taking Plectide Tablet 10. Patients with severe liver problems may require careful monitoring during treatment.

Kidney

Inform your doctor if you have kidney problems before taking Plectide Tablet 10. Severe diarrhoea associated with treatment may worsen dehydration in patients with kidney disease.

Use In Driving And Operating Machinery

Plectide Tablet 10 does not usually affect the ability to drive or operate machinery. However, avoid such activities if you feel weak or dizzy due to diarrhoea or dehydration.

Allergy

Do not take Plectide Tablet 10 if you are allergic to plecanatide or any ingredients of this medicine. Seek immediate medical attention if you develop a rash, swelling, itching, or breathing difficulty.

Children

Older Patients

Older adults may require careful monitoring during treatment, especially if severe diarrhoea or dehydration occurs.

Drug-Drug Interactions

Plectide Tablet 10 may interact with the following medicines:

Antihypertensive medicines (e.g., amlodipine, losartan): Severe diarrhoea associated with this medicine may increase the risk of dehydration and low blood pressure in some individuals taking antihypertensive medicines. Your doctor may monitor fluid status and blood pressure during treatment.
Antidiabetic medicines (e.g., insulin, metformin): Diarrhoea and reduced food intake during treatment may affect blood sugar control in some individuals. Your doctor may advise monitoring blood glucose levels if needed.
Diuretic medicines (e.g., furosemide, hydrochlorothiazide): Taking these medicines together may increase the risk of dehydration and electrolyte imbalance if severe diarrhoea occurs. Your doctor may monitor your hydration status during treatment.
Laxative medicines (e.g., lactulose, bisacodyl): Taking multiple constipation medicines together may increase the risk of excessive diarrhoea, abdominal discomfort, or dehydration. Your doctor may adjust treatment if required.

Drug-Disease Interactions

Plectide Tablet 10 should be used with caution if you have:

Mechanical gastrointestinal obstruction: This medicine should not be used in patients with known or suspected bowel obstruction because worsening intestinal symptoms may occur.
Severe diarrhoea or dehydration: Patients with dehydration may experience worsening fluid and electrolyte imbalance during treatment. Your doctor may temporarily stop treatment if severe diarrhoea occurs.
Electrolyte imbalance: Excess fluid loss due to diarrhoea may worsen sodium or potassium imbalance in some individuals. Your doctor may advise monitoring if needed.

Daily Dose

Take Plectide Tablet 10 exactly as prescribed by your doctor. The dosage and duration of treatment may vary depending on the severity of constipation, treatment response, and overall medical condition. Do not stop treatment or change the prescribed schedule without consulting your doctor.

Over Dose

Taking more than the prescribed amount of Plectide Tablet 10 may increase the risk of severe diarrhoea, dehydration, abdominal discomfort, weakness, or electrolyte imbalance. Seek immediate medical attention if overdose is suspected.

Missed Dose

If you miss a dose of Plectide Tablet 10, skip the missed dose and take the next dose at the regular time. Do not take two doses together to compensate for the missed dose.

Store Plectide Tablet 10 below 25°C in a dry place away from moisture.
Keep the medicine in the original package.
Protect from excessive heat and direct sunlight.
Keep out of reach of children.

Increase dietary fibre intake through fruits, vegetables, and whole grains if advised by your doctor to help support regular bowel movements.
Drink adequate water throughout the day to help soften stools and reduce constipation-related discomfort.
Maintain regular physical activity, such as walking or light exercise, to help improve bowel movement regularity.
Avoid delaying bowel movements, as holding stools for long periods may worsen constipation.
Develop a regular toilet routine, especially after meals, to help support healthy bowel habits.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Chronic idiopathic constipation
Drug Category	Guanylate cyclase-C agonist
Therapeutic Category	Gastrointestinal medicine

What is Plectide Tablet 10 used for?

Plectide Tablet 10 is used to help manage chronic idiopathic constipation in adults.

How does Plectide Tablet 10 help relieve constipation?

This medicine helps increase intestinal fluid secretion and improve stool movement through the intestines, which supports easier bowel movements.

Can Plectide Tablet 10 cause diarrhoea?

Yes, diarrhoea is the most common side effect associated with this medicine and may occasionally become severe.

What should I do if severe diarrhoea occurs during treatment?

Stop taking the medicine and contact your doctor immediately if severe diarrhoea develops. Maintaining adequate hydration is important during treatment.

Can Plectide Tablet 10 be used in children?

No, this medicine should not be used in children and adolescents below 18 years of age because serious dehydration may occur.

Can Plectide Tablet 10 be taken with food?

Yes, this medicine may be taken with or without food according to your doctor’s advice.

Last Updated On 28 May. 2026 | 11:35PM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead & Reviewer | 7 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 12 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

MSN House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad, Telangana 500018

Country of origin: INDIA

Expiry on or after: February 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

DrugBank. (2026). Plecanatide. DrugBank Online. https://go.drugbank.com/drugs/DB13170
U.S. Food and Drug Administration. (2017). TRULANCE (plecanatide) tablets, for oral use [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/208745lbl.pdf
National Library of Medicine. (2018, April 15). Plecanatide: MedlinePlus drug information. MedlinePlus. https://medlineplus.gov/druginfo/meds/a617020.html

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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