Mirago S 50 Combikit Tablet 14

Sun Pharmaceutical Industries Ltd

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STRIP of 14 Units

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Composition

Mirabegron (50 Mg) + Solifenacin (5 Mg)

Mirago S 50 Combikit Tablet 14 is used to manage symptoms of overactive bladder (OAB) such as urgent and frequent urination. It is a combination medicine that belongs to the class of medications known as urinary antispasmodics.

This medicine helps relieve additional symptoms associated with OAB including urge incontinence, which is the uncontrolled leakage of urine with urgency, and nocturia, which means waking up more than once during the night to urinate. It improves bladder control and reduces episodes of leakage, helping you manage your daily activities with greater comfort.

You should take this medicine orally as directed by your doctor. The appropriate dosage will be determined based on your specific condition and response to treatment. Make sure to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you experience any side effects while taking this medicine, notify your doctor immediately. Continue taking the medicine for the full duration prescribed by your doctor for optimal results.

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Mirago S 50 Combikit Tablet 14 is used for the following:

Treatment of overactive bladder
Management of urinary urgency
Control of frequent urination
Improving bladder control
Relief of urinary leakage episodes
Decreasing bladder muscle spasms
Increasing bladder capacity

Follow these instructions while taking Mirago S 50 Combikit Tablet 14:

Swallow the tablet whole with a glass of water.
Do not crush, chew, or break the tablet.
Do not stop taking this medicine without consulting your doctor.
If you have any concerns, consult your doctor.

Mirago S 50 Combikit Tablet 14 is taken orally.

Mirago S 50 Combikit Tablet 14 may have the following common side effects:

Dry mouth
Constipation
Headache
Drowsiness
Blurred vision: This refers to a lack of sharpness in your eyesight, making objects appear cloudy or out of focus.
Increased blood pressure: This occurs when the force of blood pushing against your blood vessel walls becomes higher than normal.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Mirago S 50 Combikit Tablet 14. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:

Dry mouth: Taking Mirago S 50 Combikit Tablet 14 with meals or a glass of water may help reduce this discomfort.
Constipation: Taking this medicine with breakfast may help improve your bowel movements throughout the day.

Mirago S 50 Combikit Tablet 14 contains two active ingredients:

Mirabegron (50 mg): This component works as a beta-3 adrenergic receptor agonist, which means it stimulates specific receptors in the bladder muscle called beta-3 receptors. This stimulation relaxes the detrusor muscle (the muscle surrounding the bladder), increasing the bladder's capacity and allowing it to hold more urine.
Solifenacin (5 mg): This functions as an antimuscarinic agent, also known as an anticholinergic. It blocks the action of acetylcholine, a chemical messenger in your body that causes bladder muscle contractions. By reducing these contractions, solifenacin decreases the frequency and intensity of bladder spasms, allowing your bladder to fill more completely.

Pregnancy

Mirago S 50 Combikit Tablet 14 is not advised during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Mirago S 50 Combikit Tablet 14 is not recommended for breastfeeding/lactating women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Alcohol may increase your risk of side effects like drowsiness and dizziness. It is best to consult your doctor about alcohol consumption while on Mirago S 50 Combikit Tablet 14.

Liver

If you have liver problems, discuss them with your doctor before starting Mirago S 50 Combikit Tablet 14 . Liver function may need monitoring during treatment.

Kidney

Mirago S 50 Combikit Tablet 14 requires special consideration if you have kidney impairment. Your doctor may need to adjust the dosage based on your kidney function.

Using Machines & Driving

Mirago S 50 Combikit Tablet 14 may cause drowsiness, blurred vision or dizziness in some people. If you experience these effects, avoid driving, operating machinery, or performing tasks requiring alertness until you know how this medicine affects you.

Allergy

If you have any known allergies to mirabegron, solifenacin, or any other ingredients in Mirago S 50 Combikit Tablet 14, do not take this medicine. Tell your doctor about all your allergies before starting treatment.

Children

Caution is advised while giving Mirago S 50 Combikit Tablet 14 to children under 18 years of age. Always discuss with your doctor before giving any medicine to a child.

Older Patients

Be careful while taking Mirago S 50 Combikit Tablet 14 if you have existing kidney or liver issues or are taking other medicines. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Mirago S 50 Combikit Tablet 14 interacts with the following medicines:

Anticholinergic medicines: Medicines like oxybutynin and tolterodine can increase the risk of side effects such as dry mouth, constipation, and urinary retention when taken with Mirago S 50 Combikit Tablet 14.
Antifungals: Medicines like ketoconazole can raise blood levels of solifenacin in Mirago S 50 Combikit Tablet 14, potentially increasing side effects.
Heart medicines: Digoxin levels may increase when taken with mirabegron in Mirago S 50 Combikit Tablet 14, potentially causing toxicity.
QT-prolonging medicines: Quinidine and sotalol, when combined with Mirago S 50 Combikit Tablet 14, can increase the risk of irregular heart beats.

Drug-Disease Interactions

Mirago S 50 Combikit Tablet 14 interacts with the following diseases:

Urinary retention: This medicine may worsen the inability to empty your bladder completely.
Angle-closure glaucoma: Mirago S 50 Combikit Tablet 14 can increase eye pressure in uncontrolled glaucoma.
Hypertension: Mirago S 50 Combikit Tablet 14 may further increase blood pressure in patients with existing high blood pressure.
QT prolongation: This medicine may worsen heart rhythm problems in patients with this condition.

Daily Dose

The daily dose of Mirago S 50 Combikit Tablet 14 should be taken as prescribed by your doctor. The dosage may vary based on your specific condition severity and how well you respond to treatment. Always follow your doctor's instructions and never change the dose without consulting them.

Over Dose

Taking too many Mirago S 50 Combikit Tablet 14 may cause severe dry mouth, constipation, difficulty passing urine, blurred vision, drowsiness or rapid heartbeat. If you suspect an overdose, contact your doctor or visit the nearest hospital immediately.

Missed Dose

If you forget to take your Mirago S 50 Combikit Tablet 14, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never take a double dose to make up for a forgotten tablet.

Store Mirago S 50 Combikit Tablet 14 at room temperature below 30°C.
Protect the tablets from moisture.
Do not store in the bathroom or other damp places.
Keep out of reach of children.
Do not use this medicine after the expiry date printed on the package.

Limit caffeine intake (coffee, tea, and fizzy drinks) as these can irritate your bladder and worsen overactive bladder symptoms.
Practice pelvic floor exercises regularly to strengthen the muscles that help control urination and improve bladder control.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Urinary urgency, Urinary frequency, Urge incontinence
Drug Category	Beta-3 agonist, Anticholinergic
Therapeutic Category	Overactive bladder medicine

What if I miss a dose of Mirago S 50 Combikit Tablet 14?

Take it when you remember, unless it's nearly time for your next dose. If so, skip the missed dose and continue your regular schedule. Never take a double dose.

How long does Mirago S 50 Combikit Tablet 14 take to work?

You may notice some improvement within 4 weeks, but full benefits might take 8-12 weeks. Consult your doctor if symptoms don't improve after 12 weeks.

Can I stop taking Mirago S 50 Combikit Tablet 14 once my symptoms improve?

No, don't stop without consulting your doctor. This medicine needs continuous use to control overactive bladder symptoms, which may return if stopped abruptly.

What are the most common side effects of Mirago S 50 Combikit Tablet 14?

Common side effects include dry mouth, constipation, headache, drowsiness and blurred vision. Most side effects are mild and often improve as your body adjusts.

Can I take Mirago S 50 Combikit Tablet 14 with other medicines?

Always tell your doctor about all medicines you take. Mirago S 50 Combikit Tablet 14 can interact with several medicines, potentially causing harmful effects or reducing effectiveness.

Should I take Mirago S 50 Combikit Tablet 14 with or without food?

You can take this medicine with or without food. The tablet should be swallowed whole with water and not crushed, chewed or broken.

Is Mirago S 50 Combikit Tablet 14 safe for long-term use?

Yes, this medicine is typically used long-term to manage overactive bladder symptoms. Your doctor will periodically review your condition to determine if continued use is necessary.

Last Updated On 09 Jun. 2025 | 6:09AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

SCO No. 14, Sector 5, Panchkula – 134114, Haryana

Country of origin: INDIA

Expiry on or after: February 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Mirabegron: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB08893
Astellas Pharma US, Inc. (2004). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021518s016lbl.pdf
Solifenacin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01591
Tang, Q., Zhou, S., Liu, Y., Wu, J., & Tao, R. (2022). Efficacy and safety of combination of mirabegron and solifenacin in patients with double-J stent related overactive bladder: a prospective study. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-23795-5
Herschorn, S., Chapple, C. R., Abrams, P., Arlandis, S., Mitcheson, D., Lee, K., Ridder, A., Stoelzel, M., Paireddy, A., Van Maanen, R., & Robinson, D. (2017). Efficacy and safety of combinations of mirabegron and solifenacin compared with monotherapy and placebo in patients with overactive bladder (SYNERGY study). BJU International, 120(4), 562–575. https://doi.org/10.1111/bju.13882

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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