Empaglyn L 25/5 Tablet 10

Zydus Healthcare Ltd

Strip of 10 Units

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Old MRP ₹231

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Composition

Empagliflozin (25 Mg) + Linagliptin (5 Mg)

Empaglyn L 25/5 Tablet is used to manage type 2 diabetes in adults alongside diet and exercise, and it can help reduce the risk of cardiovascular death in adults with heart disease. It is a combination medicine containing empagliflozin, an SGLT2 inhibitor, and linagliptin, a DPP-4 inhibitor.

This tablet is not for type 1 diabetes. Take it with or without food, in the dose prescribed by your doctor.

A balanced diet, regular activity and staying well hydrated support blood sugar control alongside this medicine.

Tell your doctor about any kidney problems, history of pancreatitis, urinary or genital infections or other medicines you take. Do not stop taking this medicine unless your doctor advises you to do so.

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Empaglyn L 25/5 Tablet is used to manage type 2 diabetes in adults, helping control blood sugar and, in people with heart disease, lowering the risk of cardiovascular death.

Uses of Empaglyn L 25/5 Tablet are:

Type 2 Diabetes: Improves blood sugar control alongside diet and exercise.
Cardiovascular Risk: May help reduce the risk of cardiovascular death in adults with heart disease.

Swallow the tablet whole with water.
It can be taken with or without food, preferably in the morning.
Do not chew, crush, or split the tablet.
Always follow your doctor’s instructions regarding timing and dosage.

Empaglyn L 25/5 Tablet 10 is taken orally.

Empaglyn L 25/5 Tablet may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Empaglyn L 25/5 Tablet:

Urinary and Genital: Urinary tract infections and genital yeast infections.
Respiratory: Runny nose and sore throat.
General: Increased urination.

If any side effect does not improve or becomes serious, speak to your doctor. Do not stop taking the medicine unless your doctor advises you to do so.

Management Of Side Effects:

Most side effects are temporary, generally harmless, and resolve upon discontinuing the use of Empaglyn L 25/5 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Urinary tract infections: Drink plenty of water, maintain good personal hygiene, and contact your doctor if you experience burning sensation during urination.
Abdominal pain or nausea: Take the medicine with food to reduce discomfort and consult your doctor if pain persists.
Dehydration: Increase fluid intake and avoid excessive alcohol or caffeine.

Empaglyn L 25/5 Tablet 10 contains the following components:

Empagliflozin (25 mg): It is a sodium-glucose cotransporter 2 (SGLT2). It works by blocking SGLT2 in the kidneys, leading to increased removal of glucose through urine, thereby lowering blood sugar levels.
Linagliptin (5 mg): It is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It inhibits DPP-4, increasing incretin levels, which help regulate insulin release after meals and decrease glucose production by the liver.

Pregnancy

Empaglyn L 25/5 Tablet 10 is not recommended during pregnancy as its safety has not been established. Always consult your doctor before use.

Breastfeeding

It is not known whether empagliflozin or linagliptin passes into breast milk. Breastfeeding mothers should avoid use unless specifically advised by a doctor.

Alcohol

Alcohol can affect blood sugar levels and may increase the risk of dehydration or hypoglycaemia when combined with Empaglyn L 25/5 Tablet 10. It is best to avoid alcohol during treatment.

Liver

Use Empaglyn L 25/5 Tablet 10 with caution in patients with liver problems. Linagliptin is primarily metabolised in the liver, and impaired liver function may alter medicine activity.

Kidney

Empaglyn L 25/5 Tablet 10 should be used cautiously in patients with kidney disease. If you have any kidney-related health issues, always consult your doctor before starting this medication to ensure it is safe for you.

Use In Driving And Operating Machinery

Empaglyn L 25/5 Tablet 10 may cause dizziness or drowsiness due to fluctuations in blood sugar. Avoid driving or operating machinery until you know how it affects you.

Allergy

Avoid Empaglyn L 25/5 Tablet 10 if you have a known allergy to empagliflozin, linagliptin, or any excipient. Serious allergic reactions like angioedema and anaphylaxis have been reported.

Children

Empaglyn L 25/5 Tablet 10 is not recommended in patients below 18 years of age.

Older Patients

Older adults, especially those above 70 years, may have an increased risk of dehydration, kidney impairment, and hypotension. They should take this medicine strictly under medical supervision.

Drug-Drug Interactions

Empaglyn L 25/5 Tablet 10 interacts with the following medicines:

Diuretics: Diuretic medications like furosemide and hydrochlorothiazide could enhance the potential for volume depletion when taken with Empaglyn L 25/5 Tablet 10.
Insulin and Insulin Secretagogues: Medicines like insulin or glimepiride that stimulate insulin production may increase the risk of hypoglycaemia when used with Empaglyn L 25/5 Tablet 10.
Antibiotics: Medications such as rifampin may reduce the efficacy of linagliptin, a part of this medication.

Drug-Disease Interactions

Empaglyn L 25/5 Tablet 10 interacts with the following diseases:

Pancreatitis: This tablet should be avoided in patients with a history of pancreatitis.
Heart disease: This tablet provides additional benefit but requires monitoring.
Kidney impairment: This tablet should be used with caution; discontinue if kidney function worsens.

Daily Dose

The recommended daily dose of Empaglyn L 25/5 Tablet 10 should be taken as per your doctor's advice. It varies depending on factors like the severity of your condition and how you respond to the medicine. Always adhere to the prescribed dosage and never alter it without consulting your doctor.

Over Dose

Taking more than the prescribed dose of Empaglyn L 25/5 Tablet 10 may cause severe dehydration, excessive urination, dizziness, or low blood sugar. Seek medical attention immediately.

Missed Dose

If you forget to take a dose of Empaglyn L 25/5 Tablet 10, take it as soon as you can. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not alter your dosage without your doctor's advice.

Store in a cool and dry place, away from moisture and direct sunlight.
Keep out of reach of children.
Do not use after the expiry date mentioned on the pack.

Avoid excessive sugary foods and refined carbohydrates.
Stay hydrated to counter risk of dehydration.
Monitor your blood sugar levels regularly and maintain follow-up visits with your doctor.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Type 2 diabetes mellitus, cardiovascular risk reduction in diabetes
Drug Category	SGLT2 inhibitor + DPP-4 inhibitor
Therapeutic Category	Antidiabetics

What is Empaglyn L 25/5 Tablet 10 used for?

Empaglyn L 25/5 Tablet 10 is used to improve blood sugar control in adults with type 2 diabetes mellitus and to reduce the risk of cardiovascular death in patients with established heart disease.

How does Empaglyn L 25/5 Tablet 10 work?

It contains empagliflozin, which removes excess glucose through urine, and linagliptin, which helps regulate insulin release and reduce glucose production.

Can I take Empaglyn L 25/5 Tablet 10 during pregnancy?

No, it is not recommended during pregnancy. Always consult your doctor for safer alternatives.

What should I do if I miss a dose?

Take it as soon as you remember. If it is close to your next dose, skip the missed one. Do not double the dose.

Does Empaglyn L 25/5 Tablet 10 cause low blood sugar?

The risk of hypoglycaemia is low when the tablet is taken alone, but the risk increases when combined with insulin or sulfonylureas.

Can elderly patients take Empaglyn L 25/5 Tablet 10?

Yes, but with caution, as they are at higher risk of dehydration and kidney problems. Regular monitoring is required.

Last Updated On 06 Oct. 2026 | 3:51PM (IST)

Certified Content

Written by

Dr. Divya Mandial

Medical Content Writer | 10 years

PhD in Chemistry

Reviewed by

Dr. Betina Chandolia

Lead Medical Content Reviewer | 11 years

BDS, MDS, PGCCL, PGDMH

Check out Editorial Policy

Manufacturer details

Zydus Tower, Satellite Cross Roads, Sarkhej - Gandhinagar Highway, Ahmedabad Ahmedabad GJ 380015 IN

Country of origin: INDIA

Expiry on or after: March 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

GLYXAMBI® (empagliflozin and linagliptin) tablets. (N.d.). Fda.Gov. Retrieved August 23, 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/206073s013lbl.pdf
Boehringer Ingelheim. (2021). Jardiance 10 mg and 25 mg Film-Coated Tablets Summary of Product Characteristics. https://www.ema.europa.eu/en/documents/product-information/jardiance-epar-product-information_en.pdf
Empagliflozin: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a614043.html
Empagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09038

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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CIN: U62099MH2019PTC320566

Telephone:09240250346

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